A novel method to assess initial sensitivity and acute functional tolerance to hypnotic effects of ethanol

Journal of Pharmacology and Experimental Therapeutics

Volumn 302, Issue 1, 2002, Pages 257-263

  Ponomarev, Igor ^a   Crabbe, John C ^a  

^a PORTLAND VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL;

ADAPTATION; ALCOHOL BLOOD LEVEL; ALCOHOL CONSUMPTION; ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DRUG EFFECT; HYPNOSIS; INTOXICATION; MOUSE; NONHUMAN; PHYSICAL TOLERANCE; PRIORITY JOURNAL; RIGHTING REFLEX; RISK ASSESSMENT;

ALGORITHMS; ANIMALS; BEHAVIOR, ANIMAL; BRAIN; CENTRAL NERVOUS SYSTEM DEPRESSANTS; DRUG TOLERANCE; ETHANOL; HYPNOTICS AND SEDATIVES; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MUSCULOSKELETAL EQUILIBRIUM;

EID: 0036082359     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.302.1.257     Document Type: Article

References (39)

1. Genetically determined differences in ethanol sensitivity influenced by body temperature during intoxication
2. Ethanol sleep times and hepatic alcohol and aldehyde dehydrogenase activities in mice
3. 1B receptor null mutant mice is task-dependent: Implications for behavioral assessment of genetically altered mice
4. Quantitative trait loci affecting ethanol sensitivity in BXD recombinant inbred mice
5. Sensitivity to ethanol in inbred mice: Genotypic correlations among several behavioral responses
6. Sensitivity and tolerance to ethanol in mice bred to be genetically prone or resistant to ethanol withdrawal seizures
7. Genetic determinants of sensitivity to ethanol in inbred mice
8. Factors involved in ethanol narcosis: Analysis in mice of three inbred strains
9. Direct evidence for a cause-effect link between ethanol potentiation of GABA(A) receptor function and intoxication from hyperbaric studies in C57, LS and SS mice
10. Phenotypic and genotypic relationships between ethanol tolerance and sensitivity in mice selectively bred for initial sensitivity to ethanol (SS and LS) or development of acute tolerance (HAFT and LAFT)
11. Distinctions among sedative, disinhibitory and ataxic properties of ethanol in inbred and selectively bred mice
12. Comparative pharmacokinetics of ethanol in inbred strains of mice using doses based on total body water
13. The rapid onset of tolerance to ataxic effects of ethanol in mice
14. Identification of genetic markers for initial sensitivity and rapid tolerance to ethanol-induced ataxia using quantitative trait locus analysis in BXD recombinant inbred mice
15. Acute tolerance to the ataxic effects of ethanol in short-sleep (SS) and long-sleep (LS) mice
16. N-Methyl-D-aspartate receptor responses are differentially modulated by noncompetitive receptor antagonists and ethanol in inbred long-sleep and short-sleep mice: Behavior and electrophysiology
17. Brain sensitivity to alcohol in inbred mouse strains
18. Research on tolerance: What can we learn from history
19. Tolerance to and dependence on, some non-opiate psychotropic drugs
20. Development of central nervous system sensitivity to ethanol and pentobarbital in short- and long-sleep mice
21. Error in intraperitoneal injections in rats
22. Total body water and lean mass estimated by ethanol dilution
23. Quantitative trait loci for ethanol sensitivity in the LS × SS recombinant inbred strains: Interval mapping
24. Genetic differences in the effect of alcohol upon behavior in mice
25. Calcium differentially alters behavioral and electrophysiological responses to ethanol in selectively bred mouse lines
26. Differential development and characterization of rapid acute neuronal tolerance to the depressant effects of ethanol on cerebellar Purkinje neurons of low-alcohol-sensitive and high-alcohol-sensitive rats
27. Genetic association between chronic ethanol withdrawal severity and acoustic startle parameters in WSP and WSR mice
28. Ethanol-induced activation and rapid development of tolerance may have some underlying genes in common
29. Strain differences in the development of acute tolerance to ethanol
30. A micro-method for the determination of acetaldehyde and ethanol in blood
31. Self-rating of alcohol intoxication by young men with and without family histories of alcoholism
32. An 8-year follow-up of 450 sons of alcoholic and control subjects
33. Blood and brain ethanol concentrations during absorption and distribution in long-sleep and short-sleep mice
34. Acute tolerance in inbred and selected lines of mice
35. Characterization of acute and chronic tolerance in mice selected for inherent differences in sensitivity to ethanol
36. 3H]MK-801 binding sites in short-sleep and long-sleep mice
37. MK-801-induced locomotor activity in long-sleep × short-sleep recombinant inbred mouse strains: Correlational analysis with low-dose ethanol and provisional quantitative trait loci