Detection of hCG in trophoblastic disease: The USA hCG reference service experience

Journal of Reproductive Medicine for the Obstetrician and Gynecologist

Volumn 47, Issue 6, 2002, Pages 433-444

  Cole, Laurence A ^a   Butler, Stephen ^a  

^a UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

Author keywords

Chorionic; Gonadotropins; Human; Laboratory diagnosis; Trophoblastic Neoplasms

Indexed keywords

CHORIONIC GONADOTROPIN; CHORIONIC GONADOTROPIN BETA SUBUNIT; CHORIONIC GONADOTROPIN DERIVATIVE; DACTINOMYCIN; ETOPOSIDE; FOLINIC ACID; METHOTREXATE;

CARBOXY TERMINAL SEQUENCE; CHORIOCARCINOMA; CONFERENCE PAPER; DIAGNOSTIC ACCURACY; DIAGNOSTIC ERROR; FEMALE; GLYCOSYLATION; HORMONE BLOOD LEVEL; HORMONE STRUCTURE; HUMAN; HYDATIDIFORM MOLE; PREGNANCY COMPLICATION; PRIORITY JOURNAL; STRUCTURE ANALYSIS; TROPHOBLASTIC DISEASE; UNITED STATES;

EID: 0036082029     PISSN: 00247758     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (17)

1. Early pregnancy human chorionic gonodotropin (hCG) isoforms measured by immunometric assay for choriocarcinoma-like hCG
2. Hyperglycosylated hCG (invasive trophoblast antigen) immunoassay: A new basis for gestational Down syndrome screening
3. Detection of early pregnancy forms of hCG by home pregnancy test devices
4. Utility of commonly used commercial hCG immunoassays in the diagnosis and management of trophoblastic diseases
5. Detecting and monitoring trophoblast disease: New perspectives in measuring human chorionic gonadotropin levels
6. Nicked human chorionic gonadotropin in trophoblastic disease
7. Carbohydrate and peptide structure of the α- and β-subunits of human chorionic gonadotropin from normal and aberrant pregnancy and choriocarcinoma
8. The deactivation of hCG by nicking and dissociation
9. Discordant results in human chorionic gonadotropin assays
10. False diagnosis and needles therapy of presumed malignant disease in women with false-positive human chorionic gonadotropin concentrations
11. False positive or phantom hCG result: A serious problem
12. Phantom hCG and phantom choriocarcinoma
13. False positive hCG assay results leading to unnecessary surgery and chemotherapy and needless occurrence of diabetes and coma
14. The use of heterophilic antibody blocking agent (HBT) in reducing false positive hCG results
15. Discordant human chorionic gonadotropin results: Causes and solutions
16. Falsely elevated results of radioimmunoassays using double antibody method: Arguments for a third antirabbit IgG antibody present in certain human sera
17. Heterophilic antibodies interfering with radioimmunoassay: A false-positive pregnancy test