A second-generation blood substitute (perflubron emulsion) increases the blood solubility of modern volatile anesthetics in vitro

Anesthesia and Analgesia

Volumn 95, Issue 2, 2002, Pages 368-372

  Cuignet, Olivier Y ^a   Baele, Philippe M ^b   Van Obbergh, Luc J ^b  

^a QUEEN ASTRID MILITARY HOSPITAL   (Belgium)

^b CLINIQUES UNIVERSITAIRES SAINT LUC   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

DESFLURANE; FLUOSOL; INHALATION ANESTHETIC AGENT; INTRALIPID; ISOFLURANE; PERFLUOROOCTYL BROMIDE; SEVOFLURANE;

ARTICLE; BLOOD; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG SOLUBILITY; HUMAN; PARTITION COEFFICIENT; PRIORITY JOURNAL;

EID: 0036077043     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/00000539-200208000-00023     Document Type: Article

References (18)

1. Perflubron emulsion delays blood transfusions in orthopedic surgery: European Perflubron Emulsion Study Group
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3. Fluorocarbon emulsions: The stability issue
4. The effect of Fluosol-DA on induction of inhalation anesthesia
5. Comparison of kinetics of sevoflurane and isoflurane in humans
6. Oxygen carriers as blood substitutes: Past, present, and future
7. A pilot study of the effects of a perflubron emulsion, AF 0104, on mixed venous oxygen tension in anesthetized surgical patients
8. Osmolarity determines the solubility of anesthetics in aqueous solutions at 37 degrees C
9. Increase in anesthetic uptake, excretion, and blood solubility in man after eating
10. Adiposity and the pharmacokinetics of halothane: The effect of adiposity on the maintenance of and recovery from halothane anaesthesia
11. Effect of temperature on the solubility of desflurane, sevoflurane, enflurane and halothane in blood
12. Lipid emulsions in parenteral nutrition
13. A simplified method for the measurement of volatile anesthetics in blood by gas chromatography
14. Simultaneous measurement of eight foreign gases in blood by gas chromatography
15. A new method for measurement of anaesthetic partial pressure in blood
16. Potential errors in the measurement of anesthetic partial pressure in blood
17. What solvent best represents the site of action of inhaled anesthetics in humans, rats, and dogs?
18. Reassessment of criteria for the selection of perfluorochemicals for second-generation blood substitutes: Analysis of structure/property relationships