Identification of amino acid residues of anthrax protective antigen involved in binding with lethal factor

Infection and Immunity

Volumn 70, Issue 8, 2002, Pages 4477-4484

  Chauhan, Vibha ^a   Bhatnagar, Rakesh ^a  

^a JAWAHARLAL NEHRU UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; ANTHRAX PROTECTIVE ANTIGEN; ANTIGEN; UNCLASSIFIED DRUG;

AMINO ACID ANALYSIS; AMINO ACID SEQUENCE; ANIMAL CELL; ANTHRAX; ARTICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; CYTOTOXICITY; HYDROPHOBICITY; LETHAL GENE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING;

AMINO ACID MOTIFS; ANIMALS; ANTIGENS, BACTERIAL; BACILLUS ANTHRACIS; BACTERIAL TOXINS; BINDING SITES; CELL LINE; CYTOTOXINS; ESCHERICHIA COLI; GENE EXPRESSION; MICE; MUTAGENESIS, SITE-DIRECTED; RECEPTORS, CELL SURFACE; SOLUTIONS; TRYPSIN;

EID: 0036073340     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.70.8.4477-4484.2002     Document Type: Article

References (33)

1. Identification of the cellular receptor for anthrax toxin
2. Constitutive expression of protective antigen gene of Bacillus anthracis in Escherichia coli
3. Novel non-template nucleotide addition reactions catalyzed by prokaryotic and eukaryotic DNA polymerases
4. PCR-Script Direct SK(+)vector for directional cloning of blunt-ended PCR products
5. High resolution epitope mapping of HGH receptor interactions by alanine scanning mutagenesis
6. Serum protease cleavage of Bacillus anthracis protective antigen
7. Modification of a PCR-based site-directed mutagenesis method
8. Proteolytic activation of bacterial toxins by eukaryotic cells is performed by furin and by additional cellular proteases
9. A role for PACE4 in the proteolytic activation of anthrax toxin protective antigen
10. Expression and purification of the recombinant lethal factor of Bacillus anthracis
11. Involvement of residues 147VYYEIGK153 in binding of lethal factor to protective antigen of Bacillus anthracis
12. Expression and purification of the recombinant protective antigen of Bacillus anthracis
13. A simple method for site-directed mutagenesis using the polymerase chain reaction
14. Anthrax edema toxin differentially regulates lipopolysaccharide-induced monocyte production of tumor necrosis factor alpha and interleukin-6 by increasing intracellular cyclic AMP
15. Preparation of iodine-131 labelled human growth hormone of high specific activity
16. Stability and folding of domain proteins
17. Anthrax toxin lethal factor contains a zinc metalloprotease consensus sequence which is required for lethal toxin activity
18. Anthrax toxin edema factor: A bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells
19. Purification and characterization of adenylyl cyclase from Bacillus anthracis
20. Characterization of lethal factor binding and cell receptor binding domains of protective antigen of Bacillus anthracis using monoclonal antibodies
21. Anthrax protective antigen: Prepore-to-pore conversion
22. Anthrax protective antigen forms oligomers during intoxication of mammalian cells
23. Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons
24. Crystal structure of the anthrax lethal factor
25. More than one way to make a hole
26. Crystal structure of the anthrax toxin protective antigen
27. High fidelity PCR amplification with Pfu DNA polymerase
28. A deleted variant of Bacillus anthracis protective antigen is non-toxic and blocks anthrax toxin action in vivo
29. Predictive docking of protein-protein and protein-DNA complexes
30. Studies of protein-protein interfaces: A statistical analysis of the hydrophobic effect
31. Protein-protein interfaces: Analysis of amino acid conservation in homodimers
32. Complementary action of restriction enzymes endo R-DpnI and endo R-DpnII on bacteriophage f1 DNA
33. Characterization of membrane translocation by anthrax protective antigen