Response of Gaucher bone disease to enzyme replacement therapy

British Journal of Radiology

Volumn 75, Issue SUPPL. 1, 2002, Pages

  Poll, L W ^a   Maas, M ^b   Terk, M R ^c   Roca Espiau, M ^d   Bembi, B ^e   Ciana, G ^e   Weinreb, N J ^f  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^d HOSPITAL UNIVERSITARIO MIGUEL SERVET   (Spain)

^e INSTITUTE FOR MATERNAL AND CHILD HEALTH IRCCS BURLO GAROFOLO   (Italy)

^f University Gaucher Treatment Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALGLUCERASE; FAT; GLUCOSYLCERAMIDE; GLYCOLIPID; IMIGLUCERASE; RECOMBINANT ENZYME; ENZYME; GLUCOSYLCERAMIDASE; RECOMBINANT PROTEIN;

BONE DENSITY; BONE DISEASE; BONE MARROW; BONE MINERAL; BONE PAIN; CLINICAL FEATURE; CLINICAL TRIAL; DEGRADATION; DISEASE EXACERBATION; DISEASE SEVERITY; DOSE RESPONSE; DUAL ENERGY X RAY ABSORPTIOMETRY; FUNCTIONAL ASSESSMENT; GAUCHER DISEASE; HEMATOLOGIC DISEASE; HUMAN; LIVER HYPERTROPHY; LONG TERM CARE; NUCLEAR MAGNETIC RESONANCE IMAGING; OUTCOMES RESEARCH; QUANTITATIVE ANALYSIS; REVIEW; SENSITIVITY AND SPECIFICITY; SPLEEN DISEASE; ADOLESCENT; ADULT; AGED; DRUG EFFECT; FEMALE; MALE; METABOLISM; MIDDLE AGED; REGISTER;

ADOLESCENT; ADULT; AGED; BONE DENSITY; BONE DISEASES; BONE MARROW; ENZYMES; FATS; FEMALE; GAUCHER DISEASE; GLUCOSYLCERAMIDASE; GLUCOSYLCERAMIDES; GLYCOLIPIDS; HUMANS; LONG-TERM CARE; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; RECOMBINANT PROTEINS; REGISTRIES;

EID: 0036073123     PISSN: 00071285     EISSN: None     Source Type: Journal    
DOI: 10.1259/bjr.75.suppl_1.750025     Document Type: Review

References (33)

1. Gaucher's disease: Past, present and future
2. Clinical heterogeneity among patients with Gaucher's disease
3. Glucosylceramide lipidoses: Gaucher disease
4. Enzyme therapy in type 1 Gaucher disease: Comparative efficacy of mannose-terminated glucocerebrosidase from natural and recombinant sources
5. Enzyme therapy for Gaucher disease: The first 5 years
6. Enzyme therapy in Gaucher disease type 1: Dosage efficacy and adverse effects in 33 patients treated for 6 to 24 months
7. The clinical course of treated and untreated Gaucher disease. A study of 45 patients
8. Enzyme replacement therapy for Gaucher disease: Skeletal responses to macrophage-targeted glucocerebrosidase
9. Reconversion of bone marrow in Gaucher disease treated with enzyme therapy documented by MR
10. Magnetic resonance imaging of bone marrow changes in Gaucher disease during enzyme replacement therapy: First German long-term results
11. Bone marrow response in treated patients with Gaucher disease: Evaluation by T1-weighted magnetic resonance images and correlation with reduction in liver and spleen volume
12. MR spectroscopy of bone marrow: Precision and reliability
13. Prediction of severity of Gaucher's disease by identification of mutations at DNA level
14. Gaucher disease. Clinical, laboratory, radiologic, and genetic features of 53 patients
15. Dixon quantitative chemical shift MRI for bone marrow evaluation in the lumbar spine: A reproducibility study in healthy volunteers
16. Simple proton spectroscopic imaging
17. Quantitative chemical shift imaging of vertebral bone marrow in patients with gaucher disease
18. Individualised low-dose alglucerase therapy for type 1 Gaucher's disease
19. Quantitative chemical shift imaging in Gaucher disease
20. Dixon quantitative chemical shift imaging is a sensitive tool for the evaluation of bone marrow responses to individualised doses of enzyme supplementation therapy in type 1 Gaucher disease
21. T1-W intensity ratio of vertebra and disc (V/D ratio) in bone marrow evaluation: Preliminary results in bone marrow
22. The application of the vertebra-disc ratio in a population of patients with Gaucher's disease
23. Bone density in type 1 Gaucher disease
24. Replacement therapy for inherited enzyme deficiency - Macrophage-targeted glucocerebrosidase for Gaucher's disease
25. Enzyme replacement therapy for Gaucher disease
26. Gaucher disease in the Afrikaner population of South Africa
27. Clinical characteristics of type I Gaucher's disease in Spain. Preliminary results of national survey. Spanish Group on Gaucher's Disease
28. The natural course of Gaucher disease in The Netherlands: Implications for monitoring of disease manifestations
29. Facts and fiction of modern diagnosis of type 1 Gaucher disease: The German experience in 1996
30. Clinical monitoring after cessation of enzyme replacement therapy in M. Gaucher
31. Imaging and quantifying skeletal involvement in Gaucher disease
32. Bone complications in children with Gaucher disease
33. Skeletal aspects of Gaucher disease: A review