Novel Sxra ES cell line offers hope for Y Chromosome gene-targeted mice

Genesis (United States)

Volumn 33, Issue 2, 2002, Pages 62-66

  Simpson, Elizabeth M ^a   Johnson, Kevin A ^b   Shirley, Bobbi Jo ^b   Fang, Ge Y ^c   Bayleran, Janet K ^c   Lerner, Charles P ^b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b JACKSON LABORATORY   (United States)

^c EASTERN MAINE MEDICAL CENTER   (United States)

Author keywords

Gene targeting; Sxra; Y Chromosome

Indexed keywords

GENE PRODUCT; PROTEIN SXRA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOSOME; CELL LINE; CELL MATURATION; CHROMOSOME STRUCTURE; CONTROLLED STUDY; EMBRYO; FLUORESCENCE IN SITU HYBRIDIZATION; GENE FUNCTION; GENE TARGETING; GERM CELL; MEDICAL RESEARCH; MOUSE; NONHUMAN; PRIORITY JOURNAL; REPRODUCTION; SOUTHERN BLOTTING; STEM CELL; Y CHROMOSOME; ANIMAL; C57BL MOUSE; GENE DUPLICATION; INBREEDING; TRANSGENIC MOUSE;

ANIMALS; CELL LINE; GENE DUPLICATION; GENE TARGETING; INBREEDING; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; STEM CELLS; Y CHROMOSOME;

EID: 0036072863     PISSN: 1526954X     EISSN: None     Source Type: Journal    
DOI: 10.1002/gene.10093     Document Type: Article

References (26)

1. Derivation of embryonic stem cell lines
2. The mouse Y Chromosome: Enrichment, sizing, and cloning by bivariate flow cytometry
3. Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines
4. Genetic homology and crossing over in the X and Y Chromosomes of mammals
5. Deletion of Y Chromosome sequences located outside the testis determining region can cause XY female sex reversal
6. Sex-reversed mice: XX and XO males
7. Meiotic crossing-over between the X and Y Chromosomes of male mice carrying the sex-reversing (Sxr) factor
8. Revised nomenclature for strain 129 mice
9. Male antigen defined serologically does not identify a factor responsible for testicular development
10. Harvesting, slide-making, and chromosome elongation techniques
11. Cre-mediated chromosome loss in mice
12. Purification of bacterial artificial chromosome (BAC) DNA using QIAGEN plasmid kits
13. Sex ratio and testis size in mice carrying Sxr and T(X;16)16H
14. Absence of any male-specific antigen recognized by T lymphocytes in X/XSxr' male mice
15. Spermatogenesis and the mouse Y Chromosome: Specialisation out of decay
16. Mouse Y-specific repeats isolated by whole chromosome representational difference analysis
17. Teratocarcinomas and embryonic stem cells: A practical approach
18. Successful targeting of mouse Y Chromosome genes using a site-directed insertion vector
19. Cloning and stable maintenance of 300-kilobase-pair fragments of human DNA in Escherichia coli using an F-factor based vector
20. Mutant mice and neuroscience: Recommendations concerning genetic background
21. H-Y antigen in Sxr mice detected by H-2 restricted cytotoxic T cells
22. Genetic variation among 129 substrains and its importance for targeted mutagenesis in mice
23. An interstitial deletion in mouse Y chromosomal DNA created a transcribed Zfy fusion gene
24. Sex reversal in the mouse (Mus musculus) is caused by a recurrent nonreciprocal crossover involving the X and an aberrant Y Chromosome
25. The conserved nucleotide sequences of Bkm, which define Sxr in the mouse, are transcribed
26. Subregion- and cell type-restricted gene knockout in mouse brain