Inhibition of cultured bovine aortic endothelial cell proliferation by sodium spirulan, a new sulfated polysaccharide isolated from Spirulina platensis

Planta Medica

Volumn 68, Issue 6, 2002, Pages 505-509

  Kaji, Toshiyuki ^a   Fujiwara, Yasuyuki ^a   Hamada, Chieko ^a   Yamamoto, Chika ^a   Shimada, Satomi ^a   Lee, Jung Bum ^b   Hayashi, Toshimitsu ^b  

^a HOKURIKU UNIVERSITY   (Japan)

^b UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Blue green alga; Endothelial cell; Polysaccharide; Proliferation; Sodium spirulan; Spirulina platensis

Indexed keywords

POLYSACCHARIDE SULFATE; SODIUM SPIRULAN; UNCLASSIFIED DRUG;

ANIMAL CELL; AORTA; ARTICLE; CATTLE; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DESULFURIZATION; ENDOTHELIUM CELL; GROWTH INHIBITION; MOLECULAR DYNAMICS; NONHUMAN; POLYMERIZATION; PROTEIN SYNTHESIS INHIBITION; SPIRULINA PLATENSIS; VASCULAR ENDOTHELIUM;

ANIMALS; AORTA; CATTLE; CELL DIVISION; CELLS, CULTURED; CHONDROITIN SULFATES; CYANOBACTERIA; DERMATAN SULFATE; DEXTRAN SULFATE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; HEPARIN; HEPARITIN SULFATE; HYALURONIC ACID; L-LACTATE DEHYDROGENASE; LEUCINE; MANNOSE; POLYSACCHARIDES; SODIUM; SULFATES; THYMIDINE; TRITIUM;

ALGAE; ANIMALIA; BOS TAURUS; BOVINAE; CHLOROPHYTA; CYANOBACTERIA; SPIRULINA; SPIRULINA PLATENSIS;

EID: 0036067681     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2002-32564     Document Type: Article

References (20)

1. Calcium spirulan, an inhibitor of enveloped virus replication, from a blue-green alga Spirulina platensis
2. A natural sulfated polysaccharide, calcium spirulan, isolated from Spirulina platensis: In vitro and ex vivo evaluation of anti-herpes simplex virus and anti human immunodeficiency virus activities
3. Further purification and structural analysis of calcium spirulan from Spirulina platensis
4. Structural analysis of calcium spirulan (Ca-SP)-derived oligosaccharides using electrospray ionization mass spectrometry
5. Heparin cofactor II-dependent antithrombin activity of calcium spirulan
6. Calcium spirulan as an inducer of tissue-type plasminogen activator in human fetal lung fibroblasts
7. Effects of structural modification of calcium spirulan, a sulfated polysaccharide from Spirulina platensis, on antiviral activity
8. Endothelial cell dysfunction and coagulation
9. The pathogenesis of atherosclerosis: A perspective for the 1990s
10. An improved method for the preparation of chondroitin by solvolytic desulfation of chondroitin sulfates
11. The fluorometric measurement of deoxyribonucleic acid in animal tissue with special reference to the central nervous system
12. Inhibition of human endothelial cell proliferation by heparin and steroids
13. Modulation of human endothelial cell proliferation and migration by fucoidan and heparin
14. Heparan sulfate and heparin as a potentiator or a suppressor of growth of normal and transformed vascular endothelial cells
15. The effects of epidermal growth factor and chondroitin sulfate on the animal corneal endothelial cell culture
16. Retrovirally mediated expression of decorin by macrovascular endothelial cells: Effects on cellular migration and fibronectin fibrillogenesis in vitro
17. The effect of hyaluronate and its oligosaccharides on endothelial cell proliferation and monolayer integrity
18. Evidence of involvement of CD44 in endothelial cell proliferation, migration and angiogenesis in vitro
19. Studies in vitro on the uptake and degradation of sodium hyaluronate in rat liver endothelial cells
20. Endocytosis of hyaluronic acid by rat liver endothelial cells. Evidence for receptor recycling