Research development on the immumodulatory effect of polysaccharide and its mechanism

Chinese Pharmacological Bulletin

Volumn 18, Issue 3, 2002, Pages 249-252

  Chen, Hong Liang ^a   Li, Bo Tao ^a   Zhang, Jia Xiang ^a   Li, De Fa ^a   Chang, Bi Ying ^a   Xu, Long Tao ^a  

^a Qilu Parmaceutical Factory ^*  (China)

Author keywords

Gene expression; Immunomodulation; Polysaccharides; Receptor; Signal transduction

Indexed keywords

CALCIUM ION; CYCLIC AMP; CYCLIC GMP; CYTOKINE; IMMUNOMODULATING AGENT; LYMPHOCYTE RECEPTOR; NITRIC OXIDE; POLYSACCHARIDE; PROSTAGLANDIN E2;

ARTICLE; B LYMPHOCYTE; CARBOHYDRATE ANALYSIS; CYTOKINE PRODUCTION; CYTOKINE RELEASE; GENE EXPRESSION; HUMAN; IMMUNOMODULATION; LYMPHOCYTE ACTIVATION; MOLECULAR WEIGHT; NATURAL KILLER CELL; NONHUMAN; RECEPTOR BINDING; T LYMPHOCYTE;

EID: 0036065779     PISSN: 10011978     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

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6. The function of human NK cells is enhanced by beta-glucan, a ligand of CR3 (CD11b/CD18)
7. Protective effect of L. donovani antigens using glucan as an adjuvant
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13. Soluble-glucan polysaccharide binding to thelectin site of neutrophil or natural killer cell complement receptor type 3(CD11b/CD18) generates a primed state of the receptor capable of mediating cytotoxicity of iC3b-opsonized target cells
14. Enhancement of cytokine production by macrophages stimulated with beta-D-glucan, grifolan (GRN), isolated from Grifola frondosa
15. Molecular mechanism of tumor necrosis factor-alpha production in beta -glucan (zymosan)-activated macrophages
16. 2+ influx by protein kinase C in NR8383 alveolar macrophages
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22. The cytokine stimulating activity of (1->3)-beta-D-glucans is dependent on the triple helix conformation