Monolithic matrix type transdermal drug delivery systems of pinacidil monohydrate: in vitro characterisation

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 54, Issue 2, 2002, Pages 161-164

  Aqil, M ^a   Ali, Asgar ^b  

^a New Delhi ^*  (India)

^b HAMDARD UNIVERSITY   (India)

Author keywords

In vitro permeation; In vitro release; Matrix system; Pinacidil monohydrate; Transdermal delivery

Indexed keywords

2 PROPANOL; DICHLOROMETHANE; DIMETHYL SULFOXIDE; EUDRAGIT; MACROGOL 400; PINACIDIL; POVIDONE;

ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; CONTROLLED STUDY; DRUG FORMULATION; DRUG MANUFACTURE; DRUG RELEASE; IN VITRO STUDY; INFRARED SPECTROPHOTOMETRY; NONHUMAN; RAT; TECHNIQUE; THIN LAYER CHROMATOGRAPHY; TRANSDERMAL DRUG ADMINISTRATION; ULTRAVIOLET SPECTROPHOTOMETRY;

EID: 0036056850     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0939-6411(02)00059-0     Document Type: Article

References (11)

1. Adhesive matrix type transdermal drug delivery system for nitroglycerin
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3. Pinacidil: history, basic pharmacology and therapeutic implications
4. Serum concentrations and urinary excretion of pinacidil and its major metabolite, pinacidil pyridine-N-oxide following i.v. and oral administration in healthy volunteers
5. Transdermal drug delivery - problems and promises
6. Fabrication of a diffusion cell for the determination of drug released from topical aerosol formulations
7. Vehicle effects on in vitro skin permeation of and stratum corneum affinity for model drugs caffeine and testosterone