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Volumn 50, Issue 3, 2002, Pages 179-185

Phase I and pharmacokinetic study of vinblastine and high-dose megestrol acetate

(8) Matin, Khalid a,c Egorin, Merrill J a,c Ballesteros, Michael F b,c Smith, David C a,c Lembersky, Barry a,c Day, Roger S c Johnson, Candace S a,c Trump, Donald L a,c

a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE (United States)

b UNIVERSITY OF MARYLAND (United States)

c UNIVERSITY OF PITTSBURGH CANCER INSTITUTE (United States)

Author keywords

MDR; Megestrol acetate; P gp; Vinblastine

Indexed keywords

CORTICOTROPIN; HYDROCORTISONE; MEGESTROL ACETATE; VINBLASTINE;

ADULT; AGED; ANOREXIA; ARTICLE; CLINICAL TRIAL; CONSTIPATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORTICOTROPIN BLOOD LEVEL; CULTURE MEDIUM; DIARRHEA; DISEASE SEVERITY; DOSE CALCULATION; DOSE RESPONSE; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG PROTEIN BINDING; DRUG SAFETY; DRUG TOLERABILITY; DYSPNEA; FEMALE; HUMAN; HYDROCORTISONE BLOOD LEVEL; HYPOPHYSIS ADRENAL SYSTEM; INFECTION; LEUKOPENIA; MAJOR CLINICAL STUDY; MALE; MAXIMUM TOLERATED DOSE; NAUSEA; NEUROPATHY; PHASE 1 CLINICAL TRIAL; PRIORITY JOURNAL; SOLID TUMOR; THROMBOSIS;

ADULT; AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; MALE; MEGESTROL ACETATE; MIDDLE AGED; NEOPLASMS; PITUITARY-ADRENAL SYSTEM; VINBLASTINE;

EID: 0036047665 PISSN: 03445704 EISSN: None Source Type: Journal
DOI: 10.1007/s00280-002-0484-9 Document Type: Article

Times cited : (8)

References (36)

1
- 0035883604
- A phase I study of infusional vinblastine in combination with the P-glycoprotein antagonist PSC 833 (valspodar)
- (2001) Cancer , vol.92 , pp. 1577
- Bates, S.¹ Kang, M.² Meadows, B.³ Bakke, S.⁴ Choyke, P.⁵ Merino, M.⁶ Goldspiel, B.⁷ Chico, I.⁸ Smith, T.⁹ Chen, C.¹⁰ Robey, R.¹¹ Bergan, R.¹² Figg, W.D.¹³ Fojo, T.¹⁴

2
- 0026341150
- Phase I pharmacokinetic study of D-verapamil and doxorubicin
- (1991) Br J Cancer , vol.64 , pp. 1168-1171
- Bissett, D.¹ Kerr, D.J.² Cassidy, J.³ Meredith, P.⁴ Traugott, U.⁵ Kaye, S.B.⁶

3
- 0035253714
- Phase I study of infusional paclitaxel in combination with the P-glycoprotein antagonist PSC 833
- (2001) J Clin Oncol , vol.19 , pp. 832
- Chico, I.¹ Kang, M.H.² Bergan, R.³ Abraham, J.⁴ Bakke, S.⁵ Meadows, B.⁶ Rutt, A.⁷ Robey, R.⁸ Choyke, P.⁹ Merino, M.¹⁰ Goldspiel, B.¹¹ Smith, T.¹² Steinberg, S.¹³ Figg, W.D.¹⁴ Fojo, T.¹⁵ Bates, S.¹⁶

4
- 0026572562
- Megestrol acetate reverses multidrug resistance and interacts with P-glycoprotein
- (1992) Cancer Chemother Pharmacol , vol.29 , pp. 445-449
- Fleming, G.F.¹ Amato, J.M.² Agresti, M.³ Safa, A.R.⁴

5
- 0030339279
- P-glycoprotein-mediated multidrug resistance: Experimental and clinical strategies for its reversal
- Hait WN (ed). Kluwer Academic, Dordrecht
- (1996) Drug resistance , pp. 3-38
- Ford, J.M.¹ Yang, J.M.² Hait, W.N.³

6
- 0026653953
- Multidrug resistance in human cancer
- (1992) Crit Rev Oncol Hematol , vol.12 , pp. 243-253
- Goldstein, L.J.¹ Pastan, I.² Gottesman, M.M.³

7
- 0027218689
- Biochemistry of multidrug resistance mediated by the multidrug transporter
- (1993) Annu Rev Biochem , vol.62 , pp. 385-427
- Gottesman, M.M.¹ Pastan, I.²

8
- 0026621245
- ABC transporters: From microorganisms to man
- (1992) Annu Rev Cell Dev Biol , vol.8 , pp. 67-113
- Higgins, C.F.¹

9
- 0027472165
- Mechanisms of drug resistance in ovarian cancer
- (1993) Cancer , vol.77 , pp. 644-649
- Johnson, S.W.¹ Ozols, R.F.² Hamilton, T.C.³

10
- 12944286618
- ABCG1 (ABC8), the human homolog of the Drosophila white gene, is a regulator of macrophage cholesterol and phospholipid transport
- (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 817-822
- Klucken, J.¹ Büchler, C.² Orsó, E.³ Kaminski, W.E.⁴ Porsch-Özcürümez, M.⁵ Liebisch, G.⁶ Kapinsky, M.⁷ Diederich, W.⁸ Drobnik, W.⁹ Dean, M.¹⁰ Allikmets, R.¹¹ Schmitz, G.¹²

11
- 0031780068
- Corticosteroid effects of megestrol acetate
- (1998) Endocrinologist , vol.8 , pp. 153-159
- Leinung, M.¹ Koller, E.A.² Fossler, M.J.³

12
- 0027500721
- Reversal of multidrug resistance to cancer chemotherapy
- (1993) Cancer , vol.72 , pp. 3484-3488
- Leyland-Jones, B.¹ Dalton, W.² Fisher, G.A.³ Sikic, B.I.⁴

13
- 0025302267
- Controlled trial of megestrol acetate for the treatment of cancer anorexia and cachexia
- (1990) J Natl Cancer Inst , vol.82 , pp. 1127-1132
- Loprinzi, C.L.¹ Ellison, N.M.² Schaid, D.J.³ Krook, J.E.⁴ Athman, L.M.⁵ Dose, A.M.⁶ Mailliard, J.A.⁷ Johnson, P.S.⁸ Ebbert, L.P.⁹ Geeraerts, L.H.¹⁰

14
- 0027944745
- Phase III evaluation of 4 doses of megestrol acetate as therapy for patients with cancer anorexia and/or cachexia
- (1994) Oncology , vol.51 , Issue.SUPPL. 1 , pp. 2-7
- Loprinzi, C.L.¹ Bernath, A.M.² Schaid, D.J.³ Malliard, J.A.⁴ Athmann, L.M.⁵ Michalak, J.C.⁶ Tschetter, L.K.⁷ Hatfield, A.K.⁸ Morton, R.F.⁹

15
- 0027518135
- Clinical trials of modulation of multidrug resistance
- (1993) Cancer , vol.72 , pp. 3502-3514
- Lum, B.L.¹ Fisher, G.A.² Brophy, N.A.³ Yahanda, A.M.⁴ Adier, K.M.⁵ Kaubisch, S.⁶ Halsey, J.⁷ Sikic, B.I.⁸

16
- 0033576209
- Mutations in the ABC1 gene in familial HDL deficiency with defective cholesterol efflux
- (1999) Lancet , vol.354 , pp. 1341-1346
- Marcil, M.¹ Brooks-Wilson, A.² Clee, S.M.³ Roomp, K.⁴ Zhang, L.H.⁵ Yu, L.⁶ Collins, J.A.⁷ Van Dam, M.⁸ Molhuizen, H.F.O.⁹ Loubster, O.¹⁰ Ouellette, B.F.O.¹¹ Sensen, C.W.¹² Fichter, K.¹³ Mott, S.¹⁴ Denis, M.¹⁵ Boucher, B.¹⁶ Pimstone, S.¹⁷ Genest J., Jr.¹⁸ Kastelein, J.J.P.¹⁹ Hayden, M.R.²⁰ more..

17
- 0033730357
- Phase I trial of paclitaxel plus megestrol acetate in patients with paclitaxel-refractory ovarian cancer
- (2000) Clin Cancer Res , vol.6 , pp. 4201-4204
- Markman, M.¹ Kennedy, A.² Webster, K.³ Kulp, B.⁴ Peterson, G.⁵ Belinson, J.⁶

18
- 0034691089
- Biosynthesis of a major lipofuscin fluorophore in mice and humans with ABCR-mediated retinal and macular degeneration
- (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 7154-7159
- Mata, N.L.¹ Weng, J.² Travis, G.H.³

19
- 0033786912
- Phase I and pharmacokinetic study of novobiocin in combination with VP-16 in patients with refractory malignancies
- (2000) Cancer J , vol.6 , pp. 256-265
- Murren, J.R.¹ DiStasio, S.A.² Lorico, A.³ McKeon, A.⁴ Zuhowski, E.G.⁵ Egorin, M.J.⁶ Sartorelli, A.C.⁷ Rappa, G.⁸

20
- 0033567899
- Megestrol acetate therapy and secondary adrenal suppression
- (1999) Cancer , vol.86 , pp. 1044-1049
- Naing, K.K.¹ Dewar, J.A.² Leese, G.P.³

21
- 0024533346
- Steroid hormones inhibit binding of vinca-alkaloid to multi-drug resistance related P-glycoprotein
- (1989) Biochem Biophys Res Commun , vol.158 , pp. 1066-1071
- Naito, M.¹ Yuso, K.² Tsuruo, T.³

22
- 0028577535
- Megestrol acetate in patients with AIDS and cachexia
- (1994) Ann Intern Med , vol.121 , pp. 400-408
- Oster, M.H.¹ Enders, S.R.² Samuels, S.J.³ Cone, L.A.⁴ Hooton, T.M.⁵ Browder, H.P.⁶ Flynn, N.⁷

23
- 0030580037
- Sensitization to doxorubicin resistance in breast cancer cell lines by tamoxifen and megestrol acetate
- (1996) Biochem Pharmacol , vol.52 , pp. 1097-1102
- Panasci, L.¹ Jean-Claude, B.J.² Vasilescu, D.³ Mustafa, A.⁴ Damian, S.⁵ Damian, Z.⁶ Georges, E.⁷ Liu, Z.⁸ Batist, G.⁹ Leyland-Jones, B.¹⁰

24
- 0028308901
- Multidrug resistance in cancer chemotherapy
- (1994) Invest New Drugs , vol.72 , pp. 1-13
- Patel, N.H.¹ Rothenberg, M.L.²

25
- 0027136660
- Clinical trials of agents that reverse multidrug resistance
- (1993) Cancer , vol.72 , pp. 3553-3563
- Raderer, M.¹ Scheithauer, W.²

26
- 0342811295
- Human ATP-binding cassette transporter 1 (ABC1): Genomic organization and identification of the genetic defect in the original Tangier disease kindred
- (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 12685-12690
- Remaley, A.T.¹ Rust, S.² Rosier, M.³ Knapper, C.⁴ Naudin, L.⁵ Broccardo, C.⁶ Peterson, K.M.⁷ Koch, C.⁸ Arnould, I.⁹ Prades, C.¹⁰ Duverger, N.¹¹ Funke, H.¹² Assman, G.¹³ Dinger, M.¹⁴ Dean, M.¹⁵ Chimini, G.¹⁶ Santamarina-Fojo, S.¹⁷ Fredrickson, D.S.¹⁸ Denefle, P.¹⁹ Brewer H.B., Jr.²⁰ more..

27
- 0030656445
- Modulation of vinblastine resistance in metastatic renal cell carcinoma with cyclosporine A or tamoxifen: A Cancer and Leukemia Group B study
- (1997) Clin Cancer Res , vol.3 , pp. 1977-1984
- Samuels, B.L.¹ Hollis, D.R.² Rosner, G.L.³ Trump, D.L.⁴ Shapiro, C.L.⁵ Vogelzang, N.J.⁶ Schilsky, R.L.⁷

28
- 0031027324
- Augmentation of vincristine cytotoxicity by megestrol acetate
- (1997) Cancer Chemother Pharmacol , vol.39 , pp. 333-340
- Tansan, S.¹ Koc, Y.² Aydin, H.³ Urbano, G.⁴ McCaffrey, R.⁵

29
- 0022868188
- High dose megestrol acetate in the treatment of post-menopausal women with advanced breast cancer
- (1986) Semin Oncol , vol.13 , Issue.SUPPL. 4 , pp. 20-25
- Tchekmedyian, N.S.¹ Tait, N.² Aisner, J.³

30
- 0023113054
- High dose megestrol acetate: A possible treatment for cachexia
- (1987) JAMA , vol.257 , pp. 1195-1198
- Tchekmedyian, N.S.¹ Tait, N.² Moody, M.³ Aisner, J.⁴

31
- 0023909191
- High-dose megestrol acetate in the treatment of advanced breast cancer
- (1988) Semin Oncol , vol.15 , pp. 44-49
- Tchekmedyian, N.S.¹ Tait, N.² Abrams, J.³ Aisner, J.⁴

32
- 0026445750
- High dose oral tamoxifen, a potential MDR reversal agent: A phase I trial in combination with vinblastine
- (1992) J Natl Cancer Inst , vol.84 , pp. 1811-1816
- Trump, D.L.¹ Smith, D.C.² Ellis, P.G.³ Rogers, M.P.⁴ Schold, S.C.⁵ Winer, E.P.⁶ Panella, T.J.⁷ Jordan, V.C.⁸ Fine, R.L.⁹

33
- 0028597538
- Megestrol acetate in patients with AIDS-related cachexia
- (1994) Ann Intern Med , vol.121 , pp. 393-399
- Von Roenn, J.H.¹ Armstrong, D.² Kotler, D.P.³ Cohn, D.L.⁴ Klimas, N.G.⁵ Tchekmedyian, N.S.⁶ Cone, L.⁷ Brennan, P.J.⁸ Weitzmann, S.A.⁹

34
- 0028283470
- Reversal of the human and murine multidrug-resistance phenotype with megestrol acetate
- (1994) Cancer Chemother Pharmacol , vol.34 , pp. 96-102
- Wang, L.¹ Yang, C.P.H.² Horwitz, S.B.³ Trail, P.A.⁴ Casazza, A.M.⁵

35
- 0024501045
- Progesterone interacts with P-glycoprotein in multidrug-resistant cells and in the endometrium of gravid uterus
- (1989) J Biol Chem , vol.264 , pp. 782-788
- Yang, C.P.H.¹ DePinho, S.G.² Greenberger, L.M.³ Arceci, R.J.⁴ Horwitz, S.B.⁵

36
- 0028181468
- Rapid and sensitive high-performance liquid chromatographic assay for novobiocin in human serum
- (1994) J Chromatogr B Biomed Appl , vol.655 , pp. 147-152
- Zuhowski, E.G.¹ Gutheil, J.C.² Egorin, M.J.³

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