Clinical and immunologic factors associated with the presence or absence of airways hyper-responsiveness in childhood asthma

Clinical and Experimental Allergy

Volumn 32, Issue 9, 2002, Pages 1278-1284

  Visser, M J ^a   Brand, P L P ^b   Boezen, H M ^a   Van Aalderen, W M C ^c   Kauffman, H F ^a   Postma, D S ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b Division of Paediatric Pulmonology   (Netherlands)

^c EMMA CHILDREN S HOSPITAL   (Netherlands)

Author keywords

Airways hyper responsiveness; Asthma; Child; Cytokines; Inflammation; Inhaled corticosteroids; Wheeze

Indexed keywords

CONCANAVALIN A; CORTICOSTEROID; FLUTICASONE PROPIONATE; GAMMA INTERFERON; IMMUNOGLOBULIN E; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 10; INTERLEUKIN 4; INTERLEUKIN 5;

ALLERGIC ASTHMA; ARTICLE; BRONCHUS HYPERREACTIVITY; CELL STIMULATION; CHILDHOOD; CLINICAL FEATURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DEMOGRAPHY; DISEASE ASSOCIATION; DISEASE COURSE; DRUG WITHDRAWAL; ECZEMA; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOLOGICAL PARAMETERS; MAJOR CLINICAL STUDY; MALE; MONONUCLEAR CELL; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RADIOALLERGOSORBENT TEST; SCHOOL CHILD; SYMPTOM; WHEEZING;

ANIMALS; ANIMALS, DOMESTIC; ASTHMA; BIRTH WEIGHT; BREAST FEEDING; BREATH TESTS; BRONCHIAL HYPERREACTIVITY; BRONCHOCONSTRICTOR AGENTS; CELL ADHESION MOLECULES; CHILD; CONCANAVALIN A; FEMALE; GLUCOCORTICOIDS; HUMANS; HYPERSENSITIVITY, IMMEDIATE; INTERFERON TYPE II; INTERLEUKIN-10; INTERLEUKIN-4; INTERLEUKIN-5; LEUKOCYTES, MONONUCLEAR; LOGISTIC MODELS; LYMPHOCYTE ACTIVATION; MALE; METHACHOLINE CHLORIDE; NITRIC OXIDE; RESPIRATORY FUNCTION TESTS; SMOKING; UNNECESSARY PROCEDURES;

EID: 0036042055     PISSN: 09547894     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2745.2002.01497.x     Document Type: Article

References (35)

1. Bronchial responsiveness and its measurement
2. The interrelationship among bronchial hyperresponsiveness, the diagnosis of asthma, and asthma symptoms
3. Prevalence of bronchial reactivity to inhaled methacholine in New Zealand children
4. Airway responsiveness to histamine as a test for overall severity of asthma in children
5. Effects of 22 months of treatment with inhaled corticosteroids and/or beta-2-agonists on lung function, airway responsiveness, and symptoms in children with asthma
6. One year treatment with salmeterol compared with beclomethasone in children with asthma
7. Effect of long-term treatment with inhaled corticosteroids and beta-agonists on the bronchial responsiveness in children with asthma
8. A comparison of beclomethasone, salmeterol, and placebo in children with asthma
9. The feasibility of airways hyperresponsiveness as an inclusion criterion for studies on childhood asthma
10. Asthma and wheezing in the first six years of life
11. One-year treatment with different dosing schedules of fluticasone propionate in childhood asthma. Effects on hyperresponsiveness, lung function, and height
12. Peak flow variation in childhood asthma: Relationship to symptoms, atopy, airways obstruction and hyperresponsiveness
13. Lung volumes and forced ventilatory flows. Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal. Official Statement of the European Respiratory Society
14. Does the outcome of the tidal breathing and dosimeter methods of assessing bronchial responsiveness in children with asthma depend on age?
15. Exhaled nitric oxide in children measured by tidal breathing method: Differences between asthmatics and nonasthmatic controls
16. Interleukin-4, interferon-gamma and interleukin-5 in peripheral blood of children with moderate atopic asthma
17. Prostaglandin E2 differentially modulates IL-5 gene expression in activated human T lymphocytes depending on the costimulatory signal
18. Remission of childhood asthma after long-term treatment with an inhaled corticosteroid (budesonide): Can it be achieved?
19. Risk factors for growth and decline of lung function in asthmatic individuals up to age 42 years. A 30-year follow-up study
20. Effects of reducing or discontinuing inhaled budesonide in patients with mild asthma
21. Cessation of long-term treatment with inhaled corticosteroid (budesonide) in children with asthma results in deterioration
22. Peak flow variability, methacholine responsiveness and atopy as markers for detecting different wheezing phenotypes in childhood
23. Differential immune responses to acute lower respiratory illness in early life and subsequent development of persistent wheezing and asthma
24. Exposure to pets and atopy-related diseases in the first 4 years of life
25. Does early exposure to cat or dog protect against later allergy development?
26. Genetic 'risk' for atopy is associated with delayed postnatal maturation of T-cell competence
27. Nonatopic wheezy children have reduced interferon-gamma
28. Frequencies of T cells expressing interleukin-4 and interleukin-5 in atopic asthmatic children. Comparison with atopic asthmatic adults
29. T cells subsets and cytokines in allergic and non-allergic children. II. Analysis of IL-5 and IL-10 mRNA expression and protein production
30. Interleukin-4 and interferon-gamma production in atopic and non-atopic children with asthma
31. A form of circulating ICAM-1 in human serum
32. Levels of soluble intercellular adhesion molecule-1, soluble E-selectin, tumor necrosis factor-alpha, and soluble tumor necrosis factor receptor p55 and p75 in atopic children
33. Soluble intercellular adhesion molecule-1 in sera of children with bronchial asthma exacerbation
34. Differential patterns of circulating adhesion molecules in children with bronchial asthma and acute bronchiolitis
35. Characterization of intercellular adhesion molecule-1 ectodomain (sICAM-1) as an inhibitor of lymphocyte function-associated molecule-1 interaction with ICAM-1