NMR solution structure and dynamics of the peptidyl-prolyl cis-trans isomerase domain of the trigger factor from Mycoplasma genitalium compared to FK506-binding protein

Journal of Molecular Biology

Volumn 318, Issue 4, 2002, Pages 1097-1115

  Vogtherr, Martin ^a   Jacobs, Doris M ^a   Parac, Tatjana N ^a,b   Maurer, Marcus ^c   Pahl, Andreas ^d   Saxena, Krishna ^a   Rüterjans, Heinz ^a   Griesinger, Christian ^a,e   Fiebig, Klaus M ^a  

^a GOETHE UNIVERSITY   (Germany)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c Zentaris GmbH   (Germany)

^d UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^e MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

Author keywords

FKBP; NMR structure determination; Peptidyl prolyl cis trans isomerases; Protein dynamics; Trigger factor

Indexed keywords

CYCLOPHILIN; FK 506 BINDING PROTEIN;

ARTICLE; BETA SHEET; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME STRUCTURE; MYCOPLASMA GENITALIUM; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN FOLDING; STEREOCHEMISTRY; SURFACE CHARGE;

HOMO; MYCOPLASMA; MYCOPLASMA GENITALIUM;

EID: 0036041923     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2836(02)00112-2     Document Type: Article

References (67)

1. Peptidyl-prolyl cis-trans isomerases, a superfamily of ubiquitous folding catalysts
2. The barrier to internal rotation in amides. I. Formamide
3. Protein folding in the cytosol: Chaperonin-dependent and -independent mechanisms
4. Molecular chaperones in cellular protein folding
5. NMR solution structure of h Par14 reveals similarity to the peptidyl prolyl cis/trans isomerase domain of the mitotic regulator h Pin1 but indicates a different functionality of the protein
6. Trigger factor: A soluble protein that folds pro-OmpA into a membrane-assembly-competent form
7. ProOmpA is stabilized for membrane translocation by either purified E. coli trigger factor or canine signal recognition particle
8. A ribosome-associated peptidyl-prolyl cis/trans isomerase identified as the trigger factor
9. Escherichia coli trigger factor is a prolyl isomerase that associates with nascent polypeptide chain
10. Cooperation of enzymatic and chaperone functions of trigger factor in the catalysis of protein folding
11. The amino-terminal 118 amino acids of Escherichia coli trigger factor constitute a domain that is necessary and sufficient for binding to ribosomes
12. Modular structure of the trigger factor required for high activity in protein folding
13. Recognition of protein substrates by the prolyl isomerase trigger factor is independent of proline residues
14. Overexpression of trigger factor prevents aggregation of recombinant proteins in Escherichia coli
15. Trigger factor and DnaK cooperate in folding of newly synthesized proteins
16. Polypeptide flux through bacterial Hsp70: DnaK cooperates with trigger factor in chaperoning nascent chains
17. Trigger factor associates with GroEL in vivo and promotes its binding to certain polypeptides
18. Trigger factor is induced upon cold shock and enhances viability of Escherichia coli at low temperatures
19. The minimal gene complement of Mycoplasma genitalium
20. Prolyl isomerases in a minimal cell. Catalysis of protein folding by trigger factor from Mycoplasma genitalium
21. Identification of the prolyl isomerase domain of Escherichia coli trigger factor
22. An 11.8 kDa proteolytic fragment of the E. coli trigger factor represents the domain carrying the peptidyl-prolyl cis/trans isomerase activity
23. An internal FK506-binding domain is the catalytic core of the prolyl isomerase activity associated with the Bacillus subtilis trigger factor
24. Trigger factor, one of the Escherichia coli chaperone proteins, is an original member of the FKBP family
25. HNCACB, a high-sensitivity 3D NMR experiment to correlate amide-proton and nitrogen resonances with the alpha- and beta-carbon resonances in proteins
26. Correlating backbone amide and side-chain resonances in larger proteins by multiple relayed triple resonance NMR
27. 15N resonances of the PPIase domain of the trigger factor from Mycoplasma genitalium
28. Towards a description of the conformations of denatured states of proteins. Comparison of a random coil model with NMR measurements
29. Structural and dynamical properties of a denatured protein. Heteronuclear 3D NMR experiments and theoretical simulations of lysozyme in 8 M urea
30. A new approach for applying residual dipolar couplings as restraints in structure elucidation
31. Crystallography & NMR system: A new software suite for macromolecular structure determination
32. PROCHECK: A program to check the stereochemical quality of protein structures
33. DipoCoup: A versatile program for 3D-structure homology comparison based on residual dipolar couplings and pseudocontact shifts
34. Validation of protein structure from anisotropic carbonyl chemical shifts in a dilute liquid crystalline phase
35. 2 relaxation by mutual cancellation of dipole-dipole coupling and chemical shift anisotropy indicates an avenue to NMR structures of very large biological macromolecules in solution
36. α vectors
37. X-ray structures of small ligand-FKBP complexes provide an estimate for hydrophobic interaction energies
38. Atomic structure of FKBP-FK506, an immunophilin-immunosuppressant complex
39. Atomic structure of the rapamycin human immunophilin FKBP-12 complex
40. Atomic structures of the human immunophilin FKBP-12 complexes with FK506 and rapamycin
41. β-sheet topology and the relatedness of proteins
42. Structural and functional analysis of the mitotic rotamase Pin1 suggests substrate recognition is phosphorylation dependent
43. Binding specificity of Escherichia coli trigger factor
44. Mechanism for the rotamase activity of FK506 binding protein from molecular dynamics simulations
45. A mechanism for rotamase catalysis by the FK506 binding protein (FKBP)
46. Comparative mutational analysis of peptidyl cis/trans isomerases: Active sites of Escherichia coli trigger factor and human FKBP12
47. Sequence diversification of the FK506-binding proteins in several different genomes
48. X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex
49. Characterization of ligand binding by saturation transfer difference NMR spectroscopy
50. Determination of kinetic constants for peptidyl prolyl cis-trans isomerases by an improved spectrophotometric assay
51. Use of organic solvents and small molecules for locating binding sites on proteins in solution
52. Mapping the stereospecificity of peptidyl prolyl cis/trans isomerases
53. Substrate specificities of the peptidyl prolyl cis-trans isomerase activities of cyclophilin and FK-506 binding protein: Evidence for the existence of a family of distinct enzymes
54. 2O in protein NMR. Application to sensitivity enhancement and NOE measurements
55. Frequency spectrum of NH bonds in Eglin c from spectral density mapping at multiple fields
56. 15N relaxation data exclusively
57. 15N NMR relaxation experiments at two field strengths
58. 15N NMR relaxation studies of the FK-506 binding protein: Backbone dynamics of the uncomplexed receptor
59. 15N NMR relaxation studies of the FK506 binding protein: Dynamic effects of ligand binding and implications for calcineurin recognition
60. A modular set of prokaryotic and eukaryotic expression vectors
61. XH
62. Alignment of biological macromolecules in novel nonionic liquid crystalline media for NMR experiments
63. The program XEASY for computer-supported NMR spectral analysis of biological macromolecules
64. 15N inverse detected heteronuclear NMR spectroscopy: Application to staphylococcal nuclease
65. 15N-enriched proteins
66. MOLMOL: A program for display and analysis of macromolecular structures
67. 13C NMR spectroscopy. Application to the leucine residues of staphylococcal nuclease