The efficacy of a DNA vaccine encoding herpes simplex virus type 1 (HSV-1) glycoprotein D in decreasing ocular disease severity following corneal HSV-1 challenge

Archives of Virology

Volumn 147, Issue 9, 2002, Pages 1747-1759

  Frye, T D ^a   Chiou, H C ^b   Hull, B E ^a   Bigley, N J ^a  

^a WRIGHT STATE UNIVERSITY   (United States)

^b Orchestra Therapeutics Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; ASIALOGLYCOPROTEINS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; FEMALE; HERPES SIMPLEX VIRUS VACCINES; HERPESVIRUS 1, HUMAN; IMMUNIZATION; KERATITIS, HERPETIC; MICE; MICE, INBRED BALB C; OROSOMUCOID; TRIGEMINAL GANGLION; VACCINES, DNA; VIRAL ENVELOPE PROTEINS; VIRAL LOAD;

ANIMALIA; HUMAN HERPESVIRUS 1; SIMPLEXVIRUS;

EID: 0036040371     PISSN: 03048608     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00705-002-0830-6     Document Type: Article

References (29)

1. + T cells
2. Analysis of DNA sequences by blotting and hybridization
3. Long term expression and absence of murine immune response to human interferon after intravenous delivery to the liver by polyplex and formulants
4. Quantitation of rare DNAs by PCR
5. Gential herpes and public health: Addressing a global problem
6. A novel immunization method to induce cytotoxic T lymphocyte response against plasmid-encoded herpes simplex virus type-1 glycoprotein D
7. DNA vaccines
8. Establishment of latent herpes simplex virus type I infection in resistant, sensitive, and immunodeficient mouse strains
9. The role of neutralizing antibody and T-helper subtypes in protection and pathogenesis of vaccinated mice following ocular HSV-1 challenge
10. + T cell function is sufficient for clearance of infectious virus from trigeminal ganglia and establishment of herpes simplex virus type 1 latency in mice
11. Immunization against HSV-1 keratitis with a synthetic gD peptide
12. CD4 - Positive T lymphocytes are required for the generation of the primary but not the secondary CD8 - Positive cytolytic T lymphocyte response to herpes simplex virus in C57BL/6 mice
13. Quantitative polymerase chain reaction analysis of herpes simplex virus DNA in ganglia of mice infected with replication-incompetent mutants
14. Macrophage control of herpes simplex virus type 1 replication in the peripheral nervous system
15. Biology and molecular aspects of herpes simplex and varicellazoster virus infections
16. + T lymphocytes
17. Murine response to DNA encoding herpes simplex virus type-1 glycoprotein D targeted to the liver
18. Targeted delivery of DNA encoding herpes simplex virus type-1 glycoprotein D enhances the cellular response to primary viral challenge
19. T cell receptor-γδ cells protect mice from herpes simplex virus type 1-induced lethal encephalitis
20. Reactivation of herpes simplex virus type 1 in the mouse: An in vivo study of virus antigens and immune cell infiltration
21. Zosteriform spread of herpes simplex virus as a model of recrudescence and its use to investigate the role of immune cells in prevention of recurrent disease
22. Herpes simplex virus type 2 ICP47 inhibits human TAP but not mouse TAP
23. Herpes simplex virus type 1 mutant in 1814 establishes a unique, slow progressing infection in SCID mice
24. Immunohistochemical detection of T-cell subsets and other leukocytes in paraffin-embedded rat and mouse tissues with monoclonal antibodies
25. Delivery systems for gene therapy
26. Specific inhibition of hepatitis B viral gene expression in vitro by targeted antisense oligonucleotides
27. Direct contact with herpes simplex virus-infected cells results in inhibition of lymphokine-activated killer cells because of cell-to-cell spread of the virus