Development of a second generation monoclonal single chain variable fragment antibody against Venezuelan equine encephalitis virus: Expression and functional analysis

Hybridoma and Hybridomics

Volumn 21, Issue 3, 2002, Pages 169-178

  Alvi, A Z ^a,b   Fulton, R Elaine ^b   Chau, D ^b   Suresh, M R ^c   Nagata, L P ^c  

^a SYNX Pharma Inc   (Canada)

^b CFB Suffield   (Canada)

^c UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

MONOCLONAL ANTIBODY; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; BACTERIAL STRAIN; BINDING AFFINITY; CONTROLLED STUDY; ENCEPHALOMYELITIS; ENZYME LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI; GENE EXPRESSION; MOLECULAR CLONING; NONHUMAN; PHAGEMID; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PUBLISHING; REDUCTION; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; VENEZUELAN EQUINE ENCEPHALOMYELITIS ALPHAVIRUS;

ALPHAVIRUS; BACTERIA (MICROORGANISMS); EQUIDAE; ESCHERICHIA COLI; MURINAE; VECTORS; VENEZUELAN EQUINE ENCEPHALITIS VIRUS;

EID: 0036037628     PISSN: 15368599     EISSN: None     Source Type: Journal    
DOI: 10.1089/153685902760173881     Document Type: Article

References (23)

1. Alphaviruses
2. Molecular evidence for the origin of the widespread Venezuelan equine encephalitis epizootic of 1969-1972
3. Reemergence of epidemic Venezuelan equine encephalomyelitis in South America
4. Biochemical and antigenic comparisons of the envelope glycoproteins of Venezuelan equine encephalomyelitis virus strains
5. Protein-protein interaction in an alphavirus membrane
6. Togaviridae: The viruses and their replication
7. Antigenic analysis of the surface glycoproteins of a Venezuelan equine encephalomyelitis virus (TC-83) using monoclonal antibodies
8. The neutralization site on the E2 gly-coprotein of Venezuelan equine encephalomyelitis (TC-83) virus is composed of multiple conformationally stable epitopes
9. Use of a new synthetic peptide derived monoclonal antibody to differentiate between vaccine and wild type Venezuelan equine encephalomyelitis viruses
10. Monoclonal antibodies in the diagnosis and treatment of human diseases
11. Monoclonal antibodies in diagnosis and therapy
12. Binding activities of a repertoire of single immunoglobulin variable domains secreted from Escherichia coli
13. Cloning of the immunological repertoire in Escherichia coli for generation of monoclonal catalytic antibodies: Construction of heavy chain variable region-specific cDNA library
14. Escherichia coli secretion of an active chimeric antibody fragment
15. Assembly of a functional immunoglobulin Fv fragment in Escherichia coli
16. Single chain antigen-binding proteins
17. Single chain antibody variable regions
18. Expression of engineered antibodies and antibody fragments in microorganisms
19. Development of a functional monoclonal single-chain variable fragment antibody against Venezuelan equine encephalitis virus
20. Construction of a functional single-chain variable fragment antibody against hemagglutinin from Porphymonas gingivalis
21. Antibody engineering using Escherichia coli as host