Identification of rat quantitative trait loci that regulate LPS-induced pro-inflammatory cytokine responses

Scandinavian Journal of Immunology

Volumn 56, Issue 3, 2002, Pages 248-253

  Xu, H W ^a   Wallstrom E ^a   Becanovic, K ^a   Dahlman, I ^a   Lorentzen, J C ^a,b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CYTOKINE; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CHROMOSOME; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSIVE ELEMENT; GENE CONTROL; GENE LOCATION; GENETIC LINKAGE; GENOME ANALYSIS; IN VITRO STUDY; INFLAMMATION; LINKAGE ANALYSIS; MAJOR HISTOCOMPATIBILITY COMPLEX; MICROSATELLITE MARKER; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROGENY; PROMOTER REGION; QUANTITATIVE TRAIT LOCUS; RAT; STRUCTURAL HOMOLOGY;

ANIMALS; ANIMALS, CONGENIC; HISTOCOMPATIBILITY ANTIGENS; INFLAMMATION; INTERLEUKIN-6; LINKAGE (GENETICS); LIPOPOLYSACCHARIDES; QUANTITATIVE TRAIT, HERITABLE; RATS; RATS, INBRED ACI; RATS, INBRED LEW; TUMOR NECROSIS FACTOR-ALPHA; VARIATION (GENETICS);

EID: 0036036389     PISSN: 03009475     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3083.2002.01130.x     Document Type: Article

References (53)

1. Toll-like receptors in the induction of the innate immune response
2. Mechanisms of phagocytosis in macrophages
3. Lipopolysaccharide, lipid A, and liposomes containing lipid A as immunologic adjuvants
4. Reactive oxygen species regulate activation-induced T cell apoptosis
5. Innate immunity: Impact on the adaptive immune response
6. Innate immune recognition and control of adaptive immune responses
7. Recognition of gram-negative bacteria and endotoxin by the innate immune system
8. Identification of arthritogenic adjuvants of self and foreign origin
9. Comparative expression of TNF-alpha alleles from normal and autoimmune-prone MHC haplotypes
10. Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin
11. Lipopolysaccharide binding protein as a marker of inflammation in synovial fluid of patients with arthritis: Correlation with interleukin 6 and C-reactive protein
12. Systemic macrophage activation in locally-induced experimental arthritis
13. The pathophysiology of tumor necrosis factors
14. Tumor necrosis factor identified in multiple sclerosis brain
15. Predominant pathogenic role of tumor necrosis factor in experimental colitis in mice
16. Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions
17. Mucosal immunoregulation and inflammatory bowel disease: New insights from murine models of inflammation
18. Shock and tissue injury induced by recombinant human cachectin
19. Dissociation of LPS-induced monocytic ex vivo production of granulocyte colony-stimulating factor (G-CSF) and TNF-alpha in patients with septic shock
20. Characteristics of tumor necrosis factor production in rheumatoid arthritis
21. Inherited variability of tumor necrosis factor production and susceptibility to infectious disease
22. Genetic influence on cytokine production and fatal meningococcal disease
23. Identification of genes controlling collagen-induced arthritis in mice: Striking homology with susceptibility loci previously identified in the rat
24. Identification of a new non-major histocompatibility complex genetic locus on chromosome 2 that controls disease severity in collagen-induced arthritis in rats
25. Influence of age and caloric restriction on macrophage IL-6 and TNF production
26. Comparison of the pro-inflammatory cytokine-stimulating activity of the surface-associated proteins of periodontopathic bacteria
27. MHC haplotypedependent regulation of MOG-induced EAE in rats
28. A genetic linkage map of the laboratory rat, Rattus norvegicus
29. MAPMAKER: An interactive computer package for constructing primary genetic linkage maps of experimental and natural populations
30. Systematic detection of errors in genetic linkage data
31. Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results
32. A rat genetic linkage map including 67 new microsatellite markers
33. The central MHC gene IKBL carries a structural polymorphism that is associated with HLA-A3, B7, DR15
34. Susceptibility to multiple sclerosis mediated by HLA-DRB1 is influenced by a second gene telomeric of the TNF cluster
35. On the role of tumor necrosis factor and receptors in models of multiorgan failure, rheumatoid arthritis, multiple sclerosis and inflammatory bowel disease
36. Dysregulation of adenosine A(1) receptor-mediated cytokine expression in peripheral blood mononuclear cells from multiple sclerosis patients
37. Gene interaction and single gene effects in colon tumour susceptibility in mice
38. Epistatic modifiers of autoimmunity in a murine model of lupus nephritis
39. Lipopolysaccharide signal transduction, regulation of tumor necrosis factor biosynthesis, and signaling by tumor necrosis factor itself
40. Tumor necrosis factor locus: Genetic organisation and biological implications
41. A CD14-independent LPS receptor cluster
42. Evidence for common autoimmune disease genes controlling onset, severity, and chronicity based on experimental models for multiple sclerosis and rheumatoid arthritis
43. Quantitative trait loci affecting 4-nitroquinoline 1-oxide-induced tongue carcinogenesis in the rat
44. New genetic loci that control susceptibility and symptoms of experimental allergic encephalomyelitis in inbred mice
45. Lupus susceptibility loci in New Zealand mice
46. Polygenic control of susceptibility to murine systemic lupus erythematosus
47. A locus on chromosome 15q26 (IDDM3) produces susceptibility to insulin-dependent diabetes mellitus
48. Genetic analysis of susceptibility to experimental autoimmune encephalomyelitis in a cross between SJL/J and B10.S mice
49. Identification of murine loci associated with susceptibility to chronic experimental autoimmune encephalomyelitis
50. Crosses of NOD mice with the related NON strain. A polygenic model for IDDM
51. Congenic mapping of the insulin-dependent diabetes (Idd) gene, Idd10, localizes two genes mediating the Iddl0 effect and eliminates the candidate Fcgrl
52. A full genome search in multiple sclerosis
53. A putative vulnerability locus to multiple sclerosis maps to 5p14-p12 in a region syntenic to the murine locus Eae2