Clinical utility of ABCL (Agalicus Mushroom Extract) treatment for C-type hepatitis

Japanese Pharmacology and Therapeutics

Volumn 30, Issue 2, 2002, Pages 103-107

  Inuzuka, Hayato ^a   Yoshida, Tadayoshi ^a  

^a GUNMA UNIVERSITY   (Japan)

Author keywords

glucan; GTP; Agaricus mushroom; C type hepatitis; Clinical evaluation

Indexed keywords

AGARICUS BLAZEI EXTRACT; BETA GLUCAN; GAMMA GLUTAMYLTRANSFERASE; PLANT EXTRACT; POLYSACCHARIDE; UNCLASSIFIED DRUG;

AGARICUS BLAZEI; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DISEASE SEVERITY; DRUG FORMULATION; DRUG INDUCED DISEASE; ENZYME ACTIVITY; FEMALE; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; LYMPHOCYTE; MACROPHAGE; MALE; MUSHROOM; TOXICITY;

EID: 0036033883     PISSN: 03863603     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Itoh H, Ito H, Amano H, Noda H. Inhibitory action of a (1- > 6)-beta-D-glucan-protein complex (F III-2-b) isolated from Agaricus blazei Murill ("Himematsutake") on Meth A fibrosarcoma-bearing mice and its antitumor mechanism. Jpn J Pharmacol 1994; 66 (2): 265-71.
2. Ito H, Shimamura K, Itoh H, Kawada M. Antitumor effects of a new polysaccharide-protein complex (ATOM) prepared from Agaricus blazei (Iwada strain 101) "Himematsutake" and its mechanisms in tumor-bearing mice. Anticancer Res. 1997; 17: 277-84.
3. Ebina T, Fujimiya Y. Antitumor effects of a peptide-glucan preparation extracted from Agaricus blazei in a double-grafted tumor system mice. Biotherapy. 1998; 11 (4): 259-65.
4. Preparation and specificity of antibodies to an anti-tumor beta-glucan, lentinan. Biochem Mol Biol Int 1996; 39 (4): 679-85.
5. Sorimachi K, Akimoto K, Ikehara Y, Inafuku K, Okubo A, Yamazaki S. Secetion of TNF-alpha, IL-8 and nitric oxide by macrophages activated with Agaricus blazei Murill fractions in vitro. Cell Struct Funct 2001; 26 (2): 103-8.
6. Mizuno M, Morimoto M, Minato K, Tsuchida H. Polysaccarides from Agaricus blazei stimulate lymphocyte T-cell subsets in mice. Biosci Biotechnol Biochem. 1998; 62 (3): 434-7.