-
2
-
-
0030782743
-
Antiviral drug susceptibility of human herpesvirus 8
-
J. Neyts, E. De Clercq, Antiviral drug susceptibility of human herpesvirus 8, Antimicrob. Agents Chemother. 41 (1997) 2754-2756.
-
(1997)
Antimicrob. Agents Chemother.
, vol.41
, pp. 2754-2756
-
-
Neyts, J.1
De Clercq, E.2
-
3
-
-
0035660708
-
Antiviral agents active against human herpesviruses HHV-6, HHV-7, and HHV-8
-
E. De Clercq, L. Naesens, L. De Bolle, D. Schols, Y. Zhang, J. Neyts, Antiviral agents active against human herpesviruses HHV-6, HHV-7, and HHV-8, Rev. Med. Virol. 11 (2001) 381-395.
-
(2001)
Rev. Med. Virol.
, vol.11
, pp. 381-395
-
-
De Clercq, E.1
Naesens, L.2
De Bolle, L.3
Schols, D.4
Zhang, Y.5
Neyts, J.6
-
4
-
-
0030767409
-
In vitro antiviral drug sensitivity of the Kaposi's sarcoma-associated herpesvirus
-
M.M. Medveczky, E. Horvath, T. Lund, P.G. Medveczky, In vitro antiviral drug sensitivity of the Kaposi's sarcoma-associated herpesvirus, AIDS 11 (1997) 1327-1332.
-
(1997)
AIDS
, vol.11
, pp. 1327-1332
-
-
Medveczky, M.M.1
Horvath, E.2
Lund, T.3
Medveczky, P.G.4
-
5
-
-
0033535532
-
Oral ganciclovir for patients with cytomegalovirus retinitis treated with a ganciclovir implant
-
Roche Ganciclovir Study Group
-
D.F. Martin, B.D. Kuppermann, R.A. Wolitz, A.G. Palestine, H. Li, C.A. Robinson, Oral ganciclovir for patients with cytomegalovirus retinitis treated with a ganciclovir implant. Roche Ganciclovir Study Group, N. Engl. J. Med. 340 (1999) 1063-1070.
-
(1999)
N. Engl. J. Med.
, vol.340
, pp. 1063-1070
-
-
Martin, D.F.1
Kuppermann, B.D.2
Wolitz, R.A.3
Palestine, A.G.4
Li, H.5
Robinson, C.A.6
-
6
-
-
0029812506
-
Anti-herpesvirus treatment and risk of Kaposi's sarcoma in HIV infection
-
Royal Free/Chelsea and Westminster Hospitals Collaborative Group
-
A. Mocroft, M. Youle, B. Gazzard, J. Morcinek, R. Halai, A.N. Phillips, Anti-herpesvirus treatment and risk of Kaposi's sarcoma in HIV infection. Royal Free/Chelsea and Westminster Hospitals Collaborative Group, AIDS. 10 (1996) 1101-1105.
-
(1996)
AIDS
, vol.10
, pp. 1101-1105
-
-
Mocroft, A.1
Youle, M.2
Gazzard, B.3
Morcinek, J.4
Halai, R.5
Phillips, A.N.6
-
7
-
-
0029843883
-
Use of antiherpes drugs and the risk of Kaposi's sarcoma: Data from the Multicenter AIDS Cohort study
-
M.J. Glesby, D.R. Hoover, S. Weng, N.M. Graham, J.P. Phair, R. Detels, M. Ho, A.J. Saah, Use of antiherpes drugs and the risk of Kaposi's sarcoma: data from the Multicenter AIDS Cohort Study, J. Infect. Dis. 173 (1996) 1477-1480.
-
(1996)
J. Infect. Dis.
, vol.173
, pp. 1477-1480
-
-
Glesby, M.J.1
Hoover, D.R.2
Weng, S.3
Graham, N.M.4
Phair, J.P.5
Detels, R.6
Ho, M.7
Saah, A.J.8
-
8
-
-
0033567430
-
Role of antimetabolites of purine and pyrimidine nucleotide metabolism in tumor cell differentiation
-
S. Hatse, E. De Clercq, J. Balzarini, Role of antimetabolites of purine and pyrimidine nucleotide metabolism in tumor cell differentiation, Biochem. Pharmacol. 58 (1999) 539-555.
-
(1999)
Biochem. Pharmacol.
, vol.58
, pp. 539-555
-
-
Hatse, S.1
De Clercq, E.2
Balzarini, J.3
-
9
-
-
0025361947
-
Dihydrofolate reductase as a therapeutic target
-
B.I. Schweitzer, A.P. Dicker, J.R. Bertino, Dihydrofolate reductase as a therapeutic target, FASEB J. 4 (1990) 2441-2452.
-
(1990)
FASEB J.
, vol.4
, pp. 2441-2452
-
-
Schweitzer, B.I.1
Dicker, A.P.2
Bertino, J.R.3
-
10
-
-
0027737508
-
Molecular aspects and mechanism of action of dihydrofolate reductase inhibitors
-
P.G. Hartman, Molecular aspects and mechanism of action of dihydrofolate reductase inhibitors, J. Chemother. 5 (1993) 369-376.
-
(1993)
J. Chemother.
, vol.5
, pp. 369-376
-
-
Hartman, P.G.1
-
11
-
-
0026056370
-
Pharmacokinetic justification of antiprotozoal therapy. A US perspective
-
J.D. Berman, L. Fleckenstein, Pharmacokinetic justification of antiprotozoal therapy. A US perspective, Clin. Pharmacokinet. 21 (1991) 479-493.
-
(1991)
Clin. Pharmacokinet.
, vol.21
, pp. 479-493
-
-
Berman, J.D.1
Fleckenstein, L.2
-
12
-
-
0033986103
-
Human herpesvirus 8 open reading frame 21 is a thymidine and thymidylate kinase of narrow substrate specificity that efficiently phosphorylates zidovudine but not ganciclovir
-
E.A. Gustafson, R.F. Schinazi, J.D. Fingeroth, Human herpesvirus 8 open reading frame 21 is a thymidine and thymidylate kinase of narrow substrate specificity that efficiently phosphorylates zidovudine but not ganciclovir, J. Virol. 74 (2000) 684-692.
-
(2000)
J. Virol.
, vol.74
, pp. 684-692
-
-
Gustafson, E.A.1
Schinazi, R.F.2
Fingeroth, J.D.3
-
13
-
-
0036785578
-
Human herpesvirus 8 gene encodes a functional thymidylate synthase
-
G. Gaspar, J. Neyts, E. De Clercq, Human herpesvirus 8 gene encodes a functional thymidylate synthase, J. Virol. 76 (2002) 10530-10532.
-
(2002)
J. Virol.
, vol.76
, pp. 10530-10532
-
-
Gaspar, G.1
Neyts, J.2
De Clercq, E.3
-
14
-
-
0034007479
-
Dihydrofolate reductase from Kaposi's sarcoma-associated herpesvirus
-
C.C. Cinquina, E. Grogan, R. Sun, S.F. Lin, G.P. Beardsley, G. Miller, Dihydrofolate reductase from Kaposi's sarcoma-associated herpesvirus, Virology 268 (2000) 201-217.
-
(2000)
Virology
, vol.268
, pp. 201-217
-
-
Cinquina, C.C.1
Grogan, E.2
Sun, R.3
Lin, S.F.4
Beardsley, G.P.5
Miller, G.6
-
15
-
-
0032994145
-
Human cytomegalovirus stimulates cellular dihydrofolate reductase activity in quiescent cells
-
D. Lembo, G. Gribaudo, R. Cavallo, L. Riera, A. Angeretti, L. Hertel, S. Landolfo, Human cytomegalovirus stimulates cellular dihydrofolate reductase activity in quiescent cells, Intervirology 42 (1999) 30-36.
-
(1999)
Intervirology
, vol.42
, pp. 30-36
-
-
Lembo, D.1
Gribaudo, G.2
Cavallo, R.3
Riera, L.4
Angeretti, A.5
Hertel, L.6
Landolfo, S.7
-
16
-
-
0031736036
-
Murine cytomegalovirus induces expression and enzyme activity of cellular dihydrofolate reductase in quiescent cells
-
D. Lembo, A. Angeretti, M. Gariglio, S. Landolfo, Murine cytomegalovirus induces expression and enzyme activity of cellular dihydrofolate reductase in quiescent cells, J. Gen. Virol. 79 (1998) 2803-2807.
-
(1998)
J. Gen. Virol.
, vol.79
, pp. 2803-2807
-
-
Lembo, D.1
Angeretti, A.2
Gariglio, M.3
Landolfo, S.4
-
17
-
-
0023860163
-
A gene for dihydrofolate reductase in a herpesvirus
-
J.J. Trimble, S.C. Murthy, A. Bakker, R. Grassmann, R.C. Desrosiers, A gene for dihydrofolate reductase in a herpesvirus, Science 239 (1988) 1145-1147.
-
(1988)
Science
, vol.239
, pp. 1145-1147
-
-
Trimble, J.J.1
Murthy, S.C.2
Bakker, A.3
Grassmann, R.4
Desrosiers, R.C.5
-
18
-
-
0032975917
-
Sequence and genomic analysis of a Rhesus macaque rhadinovirus with similarity to Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8
-
R.P. Searles, E.P. Bergquam, M.K. Axthelm, S.W. Wong, Sequence and genomic analysis of a Rhesus macaque rhadinovirus with similarity to Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8, J. Virol. 73 (1999) 3040-3053.
-
(1999)
J. Virol.
, vol.73
, pp. 3040-3053
-
-
Searles, R.P.1
Bergquam, E.P.2
Axthelm, M.K.3
Wong, S.W.4
-
19
-
-
0028080421
-
A common regulation of genes encoding enzymes of the deoxynucleotide metabolism is lost after neoplastic transformation
-
M. Hengstschlager, I. Mudrak, E. Wintersberger, E. Wawra, A common regulation of genes encoding enzymes of the deoxynucleotide metabolism is lost after neoplastic transformation, Cell Growth Differ. 5 (1994) 1389-1394.
-
(1994)
Cell Growth Differ.
, vol.5
, pp. 1389-1394
-
-
Hengstschlager, M.1
Mudrak, I.2
Wintersberger, E.3
Wawra, E.4
-
20
-
-
0032542248
-
Synthesis and potent antifolate activity and cytotoxicity of B-ring deaza analogues of the nonpolyglutamatable dihydrofolate reductase inhibitor N-α-(4-amino-4-deoxypteroyl)-N-δ-hemiphthaloyl-L-ornithine (PT523)
-
A. Rosowsky, J.E. Wright, C.M. Vaidya, H. Bader, R.A. Forsch, C.E. Mota, J. Pardo, C.S. Chen, Y.N. Chen, Synthesis and potent antifolate activity and cytotoxicity of B-ring deaza analogues of the nonpolyglutamatable dihydrofolate reductase inhibitor N-α-(4-amino-4-deoxypteroyl)-N-δ-hemiphthaloyl-L-ornithine (PT523), J. Med. Chem. 41 (1998) 5310-5319.
-
(1998)
J. Med. Chem.
, vol.41
, pp. 5310-5319
-
-
Rosowsky, A.1
Wright, J.E.2
Vaidya, C.M.3
Bader, H.4
Forsch, R.A.5
Mota, C.E.6
Pardo, J.7
Chen, C.S.8
Chen, Y.N.9
-
21
-
-
0030936561
-
NMR solution structure of the antitumor compound PT523 and NADPH in the ternary complex with human dihydrofolate reductase
-
J.M. Johnson, E.M. Meiering, J.E. Wright, J. Pardo, A. Rosowsky, G. Wagner, NMR solution structure of the antitumor compound PT523 and NADPH in the ternary complex with human dihydrofolate reductase, Biochemistry 36 (1997) 4399-4411.
-
(1997)
Biochemistry
, vol.36
, pp. 4399-4411
-
-
Johnson, J.M.1
Meiering, E.M.2
Wright, J.E.3
Pardo, J.4
Rosowsky, A.5
Wagner, G.6
-
22
-
-
0031794807
-
Topological mutation of Escherichia coli dihydrofolate reductase
-
M. Iwakura, T. Takenawa, T. Nakamura, Topological mutation of Escherichia coli dihydrofolate reductase, J. Biochem. (Tokyo) 124 (1998) 769-777.
-
(1998)
J. Biochem. (Tokyo)
, vol.124
, pp. 769-777
-
-
Iwakura, M.1
Takenawa, T.2
Nakamura, T.3
-
24
-
-
0029152795
-
A polycistronic transcript in transformed cells encodes the dihydrofolate reductase of herpesvirus saimiri
-
S. Whitaker, P. Geck, M.M. Medveczky, J. Cus, S.H. Kung, T. Lund, P.G. Medveczky, A polycistronic transcript in transformed cells encodes the dihydrofolate reductase of herpesvirus saimiri, Virus Genes 10 (1995) 163-172.
-
(1995)
Virus Genes
, vol.10
, pp. 163-172
-
-
Whitaker, S.1
Geck, P.2
Medveczky, M.M.3
Cus, J.4
Kung, S.H.5
Lund, T.6
Medveczky, P.G.7
-
25
-
-
0033065430
-
Identification of the R1 oncogene and its protein product from the rhadinovirus of rhesus monkeys
-
B. Damania, M. Li, J.K. Choi, L. Alexander, J.U. Jung, R.C. Desrosiers, Identification of the R1 oncogene and its protein product from the rhadinovirus of rhesus monkeys, J. Virol. 73 (1999) 5123-5131.
-
(1999)
J. Virol.
, vol.73
, pp. 5123-5131
-
-
Damania, B.1
Li, M.2
Choi, J.K.3
Alexander, L.4
Jung, J.U.5
Desrosiers, R.C.6
-
26
-
-
0029053873
-
Human cytomegalovirus stimulates thymidylate synthase in human embryonic lung cells: A possible target for anti-HCMV therapy?
-
J. Neyts, J. Verbiest, A. Meerbach, E. De Clercq, Human Cytomegalovirus stimulates thymidylate synthase in human embryonic lung cells: A possible target for anti-HCMV therapy? Nucleosides Nucleotides 14 (1995) 1153-1156.
-
(1995)
Nucleosides Nucleotides
, vol.14
, pp. 1153-1156
-
-
Neyts, J.1
Verbiest, J.2
Meerbach, A.3
De Clercq, E.4
|