Coordination of histamine H3 receptor antagonists with human adrenal cytochrome P450 enzymes

Pharmacology

Volumn 66, Issue 3, 2002, Pages 128-135

  Yang, Richard ^a   Hey, John A ^a   Aslanian, Robert ^a   Rizzo, Charles A ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Ciproxifan; Clobenpropit; Cytochrome P450 enzyme; Histamine H3 receptor antagonist; Thioperamide; Type II optical difference spectrum

Indexed keywords

4 (4 METHYL 3 PYRROLIDINYL) 1H IMIDAZOLE; CIPROXIFAN; CLOBENPROPIT; CYTOCHROME P450; HISTAMINE H3 RECEPTOR; HISTAMINE H3 RECEPTOR ANTAGONIST; IMIDAZOLE; KETOCONAZOLE; THIOPERAMIDE; ANTIHISTAMINIC AGENT;

ADRENAL GLAND; ANIMAL TISSUE; ARTICLE; CATTLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISSOCIATION CONSTANT; DRUG ANTAGONISM; MICROSOME; MITOCHONDRION; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; SPECTROSCOPY; ANIMAL; CHEMISTRY; DRUG EFFECT; ENZYMOLOGY; FEMALE; HUMAN; MALE; METABOLISM; MIDDLE AGED;

ADRENAL GLANDS; ANIMALS; CATTLE; CYTOCHROME P-450 ENZYME SYSTEM; FEMALE; HISTAMINE ANTAGONISTS; HUMANS; MALE; MICROSOMES; MIDDLE AGED; RECEPTORS, HISTAMINE H3;

EID: 0036025401     PISSN: 00317012     EISSN: None     Source Type: Journal    
DOI: 10.1159/000063794     Document Type: Article

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