Pharmacological preconditioning in rabbit myocardium is blocked by chloride channel inhibition

Cardiovascular Research

Volumn 55, Issue 3, 2002, Pages 660-671

  Batthish, Michelle ^a,b,c   Diaz, Roberto J ^a,b   Zeng, He Ping ^a,b   Backx, Peter H ^b,c   Wilson, Gregory J ^a,b,c,d  

^a HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY HEALTH NETWORK   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

Hypoxia anoxia; Ischemia; Myocytes; Preconditioning

Indexed keywords

2 CHLORO 6 N CYCLOPENTYLADENOSINE; ADENOSINE RECEPTOR STIMULATING AGENT; CHLORIDE CHANNEL; CHLORIDE CHANNEL BLOCKING AGENT; CHLORIDE ION; INDANYLOXYACETIC ACID 94; N6 2 (4 AMINOPHENYL)ETHYLADENOSINE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C INHIBITOR; UNCLASSIFIED DRUG; (2 CYCLOPENTYL 6,7 DICHLORO 2 METHYL 1 OXO 5 INDANYLOXY)ACETIC ACID; 2 CHLORO N(6)CYCLOPENTYLADENOSINE; 2-CHLORO-N(6)CYCLOPENTYLADENOSINE; ADENOSINE; ADENOSINE RECEPTOR; DRUG DERIVATIVE; ENZYME ACTIVATOR; GLYCOLIC ACID DERIVATIVE; N(6) 2 (4 AMINOPHENYL)ETHYLADENOSINE; N(6)-2-(4-AMINOPHENYL)ETHYLADENOSINE; PROTEIN KINASE C;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; HEART INFARCTION PREVENTION; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; NONHUMAN; PRIORITY JOURNAL; RABBIT; ANIMAL; CELL CULTURE; DOSE RESPONSE; DRUG EFFECT; HEART INFARCTION; HEART MUSCLE; METABOLISM; METHODOLOGY; PATHOLOGY; PERFUSION;

ADENOSINE; ANIMAL; CELLS, CULTURED; CHLORIDE CHANNELS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATORS; GLYCOLATES; ISCHEMIC PRECONDITIONING, MYOCARDIAL; MYOCARDIAL INFARCTION; MYOCARDIUM; PERFUSION; PROTEIN KINASE C; RABBITS; RECEPTORS, PURINERGIC P1; SUPPORT, NON-U.S. GOV'T; TETRADECANOYLPHORBOL ACETATE; ANIMALS;

EID: 0036023948     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(02)00454-6     Document Type: Article

References (42)

1. Preconditioning with ischemia: A delay of lethal cell injury in ischemic myocardium
2. Chloride channel inhibition blocks the protection of ischemic preconditioning and hypo-osmotic stress in rabbit ventricular myocardium
3. Reactive oxygen species released from mitochondria during brief hypoxia induce preconditioning in cardiomyocytes
4. No confirmation for a causal role of volume-regulated chloride channels in ischemic preconditioning in rabbits
5. Chloride channel inhibition does block the protection of ischemic preconditioning in myocardium
6. 3+-sensitive cation current and cell volume regulation in rabbit ventricular myocytes
7. Stretch-activated channels blockers modulate cell volume in cardiac ventricular myocytes
8. - costransport in the regulatory volume decrease of newborn rat cardiomyocytes
9. Explosive swelling of myocardial cells irreversibly injured by transient ischemia
10. Volume regulation and plasma membrane injury in aerobic, anaerobic, and ischemic myocardium in vitro
11. Adenosine and preconditioning revisited
12. Adenosine receptor specificity in preconditioning of isolated rabbit cardiomyocytes: Evidence of A3 receptor involvement
13. Intravenous pretreatment with A1-selective adenosine analogues protects the heart against infarction
14. Activation of chloride current by purinergic stimulation in guinea pig heart cells
15. Preconditioning protects ischemic rabbit heart by protein kinase C activation
16. - currents in feline ventricular myocytes
17. Phorbol ester activation of chloride current in guinea-pig ventricular myocytes
18. - channel activation in rabbit ventricular myocytes
19. Effects of the protein phosphatase inhibitors okadaic acid and calyculin A on metabolically inhibited and ischemic isolated myocytes
20. Attachment and maintenance of adult rabbit cardiac myocytes in primary cell culture
21. Different types of blockers of the intermediate-conductance outwardly rectifying chloride channel in epithelia
22. Purification and reconstitution of chloride channels from kidney and trachea
23. Epithelial chloride channel: Development of inhibitory ligands
24. Swelling-induce chloride-sensitive current in canine atrial cells revealed by whole-cell patch-clamp method
25. Concentration-response relationships for adenosine agonists during preconditioning of rabbit cardiomyocytes
26. Preconditioning of isolated rabbit cardiomyocytes: Effects of glycolytic blockade, phorbol esters, and ischaemia
27. 1 angiotensin II receptors abolishes ischemic preconditioning in isolated rabbit hearts
28. The PKC activator PMA preconditions rabbit heart in the presence of adenosine receptor blockade: Is 5′-nucleotidase important?
29. Ischemic preconditioning induces selective translocation of protein kinase C isoforms ε and η in the heart of conscious rabbits without subcellular redistribution of total protein kinase C activity
30. 1-selective adenosine agonist preconditions rabbit heart
31. Evidence that the adenosine A3 receptor may mediate the protection afforded by preconditioning in the isolated rabbit heart
32. Swelling-activated chloride channels as effectors of ischemic preconditioning?
33. Protection against infarction afforded by preconditioning is mediated by A1 adenosine receptors in rabbit heart
34. Characterization of an angiotensin II-activated chloride current in rabbit sino-atrial cells
35. Tyrosine protein kinase inhibitors prevent activation of cardiac swelling-induced chloride current
36. Protein tyrosine kinase is downstream of protein kinase C for ischemic preconditioning's anti-infarct effect in the rabbit heart
37. Myocardial ischemia revisited. The osmolar load, membrane damage, and reperfusion
38. Tissue osmolarity, cell swelling, and reperfusion in acute regional myocardial ischemia in the isolated porcine heart
39. Cell swelling and ion transport pathways in cardiac myocytes
40. Hypotonically induced calcium increase and regulatory volume decrease in newborn rat cardiomyocytes
41. Length, width, and volume changes in osmotically stressed myocytes
42. K-Cl cotransport: Properties and molecular mechanism