Impact of iron dextran on polymorphonuclear cell function among hemodialysis patients

Clinical Nephrology

Volumn 58, Issue 2, 2002, Pages 134-142

  Guo, D ^a   Jaber, B L ^a   Lee, S ^a   Perianayagam, M C ^a   King, A J ^a   Pereira, B J G ^a   Balakrishnan, V S ^a  

^a TUFTS MEDICAL CENTER   (United States)

Author keywords

Bacterial infections; Hemodialysis; Iron dextran; PMN dysfunction

Indexed keywords

CARBON DIOXIDE; DEXFERUM; FERRIC GLUCONATE; FLUORESCENT DYE; FORMYLMETHIONYLLEUCYLPHENYLALANINE; HYDROGEN PEROXIDE; IRON; IRON DERIVATIVE; IRON DEXTRAN; PHORBOL 13 ACETATE 12 MYRISTATE;

APOPTOSIS; ARTICLE; ATTENUATION; BLOOD SAMPLING; CELL FUNCTION; CELL VIABILITY; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; DRUG EFFECT; EXPOSURE; FLOW CYTOMETRY; HEMODIALYSIS; HEMODIALYSIS PATIENT; HEPARINIZATION; HUMAN; HUMAN CELL; IN VITRO STUDY; INCUBATION TIME; KIDNEY FAILURE; PHAGOCYTOSIS; POLYMORPHONUCLEAR CELL; STAPHYLOCOCCUS AUREUS; TEMPERATURE; ADULT; AGED; CHRONIC KIDNEY FAILURE; COMPARATIVE STUDY; DOSE RESPONSE; FEMALE; MALE; MIDDLE AGED; NEUTROPHIL; PATHOPHYSIOLOGY; PHYSIOLOGY; RENAL REPLACEMENT THERAPY; TREATMENT OUTCOME;

ADULT; AGED; CELL PHYSIOLOGY; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; IRON-DEXTRAN COMPLEX; KIDNEY FAILURE, CHRONIC; MALE; MIDDLE AGED; NEUTROPHILS; RENAL DIALYSIS; TREATMENT OUTCOME;

EID: 0036023015     PISSN: 03010430     EISSN: None     Source Type: Journal    
DOI: 10.5414/cnp58134     Document Type: Article

References (42)

1. Current concepts in iron metabolism
2. Hemosiderosis in hemodialysis patients
3. Increased susceptibility to membrane lipid peroxidation in renal failure
4. Bleomycin detectable free iron is present in patients on intravenous iron therapy
5. Iron overload in hemodialysis patients increases the risk of bacteremia: A prospective study
6. Ageing and the neutrophil: No appetite for killing?
7. Immune dysfunction in uremia
8. Frequent IV iron dosing is associated with higher infectious deaths
9. Recombinant human erythropoietin: Implications for nephrology
10. Impairment of phagocyte oxidative metabolism in hemodialyzed patients with iron overload
11. Non-transferrin-bound iron in plasma or serum from patients with idiopathic hemochromatosis
12. The catalytic decomposition of hydrogen peroxide by iron salts
13. Simultaneous measurement by flow cytometry of phagocytosis and hydrogen peroxide production of neutrophils in whole blood
14. Oxidative metabolism and phagocytosis of polymorphonuclear leukocytes in patients with chronic renal failure
15. Risk factors for bacterial infections in chronic hemodialysis adult patients: A multicentre prospective survey
16. EPIBACDIAL: A multicenter prospective study of risk factors for bacteremia in chronic hemodialysis patients
17. Polynuclear iron complexes impair the function of polymorphonuclear granulocytes
18. i and carbohydrate metabolism of PMNL of dialysis patients
19. Alterations in chemotactic factor-induced responses of neutrophils and monocytes from chronic dialysis patients
20. Activation of 5-lipoxygenase and related cell membrane lipoperoxidation in hemodialysis patients
21. Poor response to erythropoetin should be fully investigated and treated
22. Septicaemia due to yersinia enterocolitica after oral overdoses of iron
23. Laboratory manual of neutrophil function
24. The adverse effect of iron repletion on the course of certain infections
25. Clinical Practice Guidelines for the Treatment of Anemia of Chronic Renal Failure
26. Neutrophil impairment associated with iron therapy in hemodialysis patients with functional iron deficiency
27. The formation of free radicals and the consequences of their reaction in vivo
28. Host defenses and infectious complications in maintenance hemodialysis patients
29. Vitamin E attenuates oxidative stress induced by intravenous iron in patients on hemodialysis
30. Antioxidant enzymes activity in polymorphonuclear leukocytes in chronic renal failure
31. Importance of iron supply for erythropoietin therapy
32. Comparative look at intravenous iron agents: Pharmacology, efficacy, and safety of iron dextran, iron saccharate, and ferric gluconate
33. Critical role of iron overload in the increased susceptibility of hemodialysis patients to bacterial infections: Beneficial effects of desferrioxamine
34. Deferoxamine enhances phagocytic function of human polymorphonuclear leukocytes
35. Effect of iron (III) in the presence of various ligands on the phagocytic and metabolic activity of human polymorphonuclear leukocytes
36. Iron dextran pharmacokinetics in iron-deficient hemodialysis patients
37. Infectious morbidity and defects of phagocytic function in end-stage renal disease: A review
38. Polymorphonuclear leukocyte oxidative burst is enhanced in patients with chronic renal insufficiency
39. Iron and infection
40. Effect of age on human neutrophil function
41. "Oversaturation" of transferrin after intravenous ferric gluconate (Ferrlecit) in hemodialysis patients