Solid, solution, and antitumor activity studies of mixed-ligand complexes with adenine-5-bromouracil base pair

Synthesis and Reactivity in Inorganic and Metal-Organic Chemistry

Volumn 32, Issue 5, 2002, Pages 853-872

  Singh, Rajender ^a   Tyagi, Sadhna ^a   Singh, Sudha ^b   Singh, Sukh Mahendra ^a   Singh, Udai P ^a  

^a INDIAN INSTITUTE OF TECHNOLOGY ROORKEE   (India)

^b BANARAS HINDU UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

5 BROMOURACIL; ADENINE DERIVATIVE; ALCOHOL; CADMIUM DERIVATIVE; COBALT COMPLEX; COPPER COMPLEX; LIGAND; METAL COMPLEX; THYMIDINE DERIVATIVE; ZINC COMPLEX;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; AQUEOUS SOLUTION; ARTICLE; BASE PAIRING; CELL VIABILITY; CONTROLLED STUDY; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; IONIC STRENGTH; LYMPHOMA CELL LINE; MOUSE; NONHUMAN; PH; PHYSICAL CHEMISTRY; SPECTROSCOPY; TEMPERATURE; X RAY DIFFRACTION;

EID: 0036022913     PISSN: 00945714     EISSN: None     Source Type: Journal    
DOI: 10.1081/SIM-120005607     Document Type: Article

References (32)

1. Stryer, L. Biochemistry; 4th Edition; W. H. Freeman and Company, New York, 1995.
2. Nobih, I.; Ansary, E. Genetic Studies on Fresh Water Snails, Specific Intermediate Host for Schistosomiasis. 3. Chemical Mutation Through Incorporation of 5-Bromouracil into Deoxyribonucleic Acids (DNA). Cell Mol. Biol. 1981, 27 (2-3), 271-275.
3. Heidelberger, C.; Chaudhuri, N.K.; Danneberg, P.; Mooren, D.; Griesbach, L.; Duschinsky, R.; Schnitzer, R.J.; Pleven, E.; Scheiner, J. Fluorinated Pyrimidines a New Class of Tumor-Inhibitory Compounds. Nature 1957, 179, 663-666.
4. Iigo, M.; Kuretani, K.; Hoshi, A. Relationship between Antitumor Effect and Metabolites of 5-Fluorouracil in Combination Treatment with 5-Fluorouracil and Guanosine in Ascites Sarcoma 180 Tumor System. Cancer Res. 1983, 43 (12), 5687-5691; Effect of Guanosine on Antitumor Activity of Fluorinated Pyrimidines against P 388 Leukemia. Cancer Chemother Pharmacol. 1983, 13 (2), 86-91.
5. Iigo, M.; Kuretani, K.; Hoshi, A. Relationship between Antitumor Effect and Metabolites of 5-Fluorouracil in Combination Treatment with 5-Fluorouracil and Guanosine in Ascites Sarcoma 180 Tumor System. Cancer Res. 1983, 43 (12), 5687-5691; Effect of Guanosine on Antitumor Activity of Fluorinated Pyrimidines against P 388 Leukemia. Cancer Chemother Pharmacol. 1983, 13 (2), 86-91.
6. Rosenberg, B.; Van Camp, L. Successful Regression of Large Solid Sarcoma 180 Tumors by Platinum Compounds. Cancer Res. 1970, 30 (6), 1799-1803.
7. Tominaga, T.; Yoshida, Y.; Kasaki, G.; Kukihara, M. Effect of 5-Fluorouracil and UFT on Experimental Liver Metastasis Model of Colorectal Cancer Using Mouse Colon-26 Cells. Jpn. J. Cancer Res. 1993, 84, 78-82.
8. Wurzer, J.C.; Tallarida, R.J.; Sirover, M.A. New Mechanism of Action of the Cancer Chemotherapeutic Agent 5-Fluorouracil in Human Cells. J. Pharmacol Exp Ther. 1994, 269 (1), 39-44.
9. Singh, U.P.; Ghose, R.; Ghose, A.K.; Singh, R.K.; Sodhi, A.; Geeta, B. Antitumor Activity Studies of Some Synthesised Transition Metal Complexes both in vivo and in vitro. Indian J. Cancer Chemother. 1991, 13, 45-52.
10. Vogel, A.I. Textbook of Quantitative Chemical Analysis; 5th Edn.; ELBS Longman, UK, 1989.
11. Azaroff, L.V. Elements of X-ray Crystallography. New York, 1968.
12. Singh, S.; Ghose, A.K. Metal Ion Interactions with Nucleic Acid Base Pairs in Solution-A Potentiometric Study. J. Indian Chem Soc. 1996, 73, 650-653.
13. Ueda, N.; Shah, S.V. Role of Interacellular Calcium in Hydrogen Peroxide-Induced Renal Tubular Cell Injury. Am. J. Physiol. 1992, 263 (2), 214-221.
14. Singh, U.P.; Ghose, R.; Ghose, A.K.; Sodhi, A.; Singh, S.M.; Singh, R.K. The Effect of Histidine on the Structure and Antitumor Activity of Metal 5-Halouracil Complexes. J. Inorg Biochem. 1989, 37, 325-339.
15. Kerr, J.F.R.; Wyllic, A.H.; Curie, A.R. Apoptosis: A Basic Biological Phenomenon with Wide Ranging Implication in Tissue Kinetics. Br. J. Cancer 1972, 26, 239-257.
16. Savoie, R.; Jutier, J.-J.; Prizant, L.; Beauchamp, A.L. Raman and Infrared Spectra of Methylmercury Complexes of Adenine. Spectrochim. Acta 1982, 38 (5), 561-564.
17. Singh, U.P.; Ghose, R.; Ghose, A.K. Characterization of Metal Chelation with a Mutagenic Agent, 5-Bromouracil. Bull. Chem. Soc. Jpn. 1990, 63, 1226-1229.
18. Speca, A.N.; Mikulski, C.M.; Iaconianni, F.J.; Pyttewski, L.L.; Karayannis, N.M. Adenine Complexes with Perchlorate from Ethanol-Triethyl Orthoformate. Inorg. Chim. Acta 1979, 37 (2), L 551-L 553.
19. Nakamoto, K. Infrared Spectra of Inorganic and Coordination Compounds; 3rd Edn.; Wiley Interscience, New York 1970.
20. Mikulski, C.M.; Braccia, D.; Delacato, D.; Fleming, J.; Fleming, D.; Karayannis, N.M. Gold(III) and Rhodium(III) Chloride Adducts with Adenine. Inorg. Chim. Acta 1985, 106 (3), L 13-L 15.
21. Sarkar, A.R.; Ghosh, P. Interaction of Divalent Metal Ions with Uracil. I. Oxygen Coordinating Uracil Complexes of Mn(II), Fe(II), Co(II), Ni(II) and Cu(II). Inorg. Chim. Acta 1983, 78 (3), L 39-L 42.
22. Goodgame, M.; Johns, K.W. Metal Complexes of Uracil and Thymine. J. Chem. Soc. Dalton Trans. 1977, (17), 1680-1683; Metal Complexes of Uridine and Thymidine. J. Chem. Soc. Dalton Trans. 1978, (10), 1294-1297.
23. Goodgame, M.; Johns, K.W. Metal Complexes of Uracil and Thymine. J. Chem. Soc. Dalton Trans. 1977, (17), 1680-1683; Metal Complexes of Uridine and Thymidine. J. Chem. Soc. Dalton Trans. 1978, (10), 1294-1297.
24. Lever, A.B.P. Inorganic Electronic Spectroscopy; Elsevier, Amsterdam, 1968.
25. Cotton, F.A.; Wilkinson, G. Advanced Inorganic Chemistry; 5th Edn.; Wiley Interscience, New York, 1988.
26. Motekaitis, R.J.; Martell, A.E. Detemination and Use of Stability Constants; VCH Publishers, New York, 1989.
27. Mohamed, M.S.; Khater, M.M.; Shonkry, E.M. Mixed Ligand Complexes of Mn(II), Co(II), Ni(II), Cu(II) and Zn(II) with Nitrilotriacetic Acid as a Primary Ligand and Sulphadiazine as a Secondary Ligand. Indian J Chem. 1986, 25 (5), 488-490.
28. Lee, J.D. Concise Inorganic Chemistry; 4th Edn.; Chapman and Hall Ltd, London, 1991.
29. Sekhon, B.S. Stability Constants of Hg(II) and Be(II) Complexes with 5-Substituted Uracils. J. Indian Chem. Soc. 1987, 64 (5), 308-309.
30. + Ions in Adenine and Cytosine. Inorg. Chim. Acta 1983, 80 (4), L 57-L 58.
31. Reddy, P.R.; Reddy, H.M. Influence of Secondary Ligand on the Stability of Metal-Xanthosine Complexes in Solution. J. Chem. Soc. Dalton Trans. 1985, 239-242.
32. Schwartz, L.M.; Osborne, B.A. Programmed Cell Death, Apoptosis, and Killer Genes. Immunology Today 1993, 14, 582-590.