Syn3 provides high levels of intravesical adenoviral-mediated gene transfer for gene therapy of genetically altered urothelium and superficial bladder cancer

Cancer Gene Therapy

Volumn 9, Issue 8, 2002, Pages 687-691

  Yamashita, Motoyuki ^a   Rosser, Charles J ^a   Zhou, Jain Hua ^a   Zhang, Xin Qiao ^a   Connor, Robert J ^b   Engler, Heidrun ^b   Maneval, Daniel C ^b   Karashima, Takashi ^a   Czerniak, Bogdan A ^a   Dinney, Colin P N ^a   Benedict, William F ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Adenoviral mediated transfer; Intravesical gene therapy; Superficial bladder cancer

Indexed keywords

ADENOVIRUS VECTOR; ALCOHOL; BETA GALACTOSIDASE; POLYAMIDE; SYN 3; UNCLASSIFIED DRUG; ARABIDOPSIS PROTEIN; CELL CYCLE PROTEIN; SYN3 PROTEIN, ARABIDOPSIS;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLADDER CANCER; COXSACKIE VIRUS; GENE EXPRESSION; GENE THERAPY; GENE TRANSFER; GENETIC ENGINEERING; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; SUPERFICIAL CANCER; SWINE; UROTHELIUM; VIRAL GENE DELIVERY SYSTEM; ADENOVIRUS; ANIMAL; CELL CULTURE; FEMALE; GENE VECTOR; GENETIC TRANSFECTION; GENETICS; METABOLISM; NUDE MOUSE;

ADENOVIRIDAE; ANIMAL; ARABIDOPSIS PROTEINS; CELL CYCLE PROTEINS; FEMALE; GENE THERAPY; GENETIC VECTORS; HUMAN; MICE; MICE, NUDE; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; SWINE; TRANSFECTION; TUMOR CELLS, CULTURED; UROTHELIUM; ANIMALS; HUMANS;

ADENOVIRIDAE; ANIMALIA; COXSACKIEVIRUS; DNA VIRUSES; SUS SCROFA;

EID: 0036021904     PISSN: 09291903     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cgt.7700488     Document Type: Article

References (11)

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8. Loss of adenoviral receptor expression in human bladder cancer cells: A potential impact on the efficacy of gene therapy
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10. Genetic modeling of urinary bladder carcinogenesis
11. Ethanol improves adenovirus-mediated gene transfer and expression to the bladder epithelium of rodents