Differential effects of aprotinin and tranexamic acid on endotoxin desensitization of blood cells induced by circulation through an isolated extracorporeal circuit

Journal of Cardiothoracic and Vascular Anesthesia

Volumn 16, Issue 4, 2002, Pages 447-451

  Asehnoune, Karim ^a   Dehoux, Monique ^a   Leçon Malas, Véronique ^b   Toueg, Marie Laure ^b   Gonieaux, Marie Hélène ^c   Omnes, Laurence ^d   Desmonts, Jean Marie ^a   Durand, Geneviève ^a   Philip, Ivan ^a  

^a BICHAT HOSPITAL   (France)

^b Laboratory technician   (France)

^c Nurse of Anesthesia   (France)

^d Perfusionist   (France)

Author keywords

Aprotinin; Cardiopulmonary bypass (CPB); Endotoxin tolerance; IL 10; IL 8; Interleukin (IL) 6; Tranexamic acid; Tumor necrosis factor (TNF)

Indexed keywords

ANTIFIBRINOLYTIC AGENT; APROTININ; ENDOTOXIN; INTERLEUKIN 10; INTERLEUKIN 6; INTERLEUKIN 8; SERINE PROTEINASE INHIBITOR; TRANEXAMIC ACID; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; ESCHERICHIA COLI LIPOPOLYSACCHARIDE;

ARTICLE; BLOOD CELL; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DESENSITIZATION; DRUG EFFECT; EXTRACORPOREAL CIRCULATION; HUMAN; METABOLISM; REFERENCE VALUE; TIME; ADULT; AGED; BLOOD SAMPLING; CARDIOPULMONARY BYPASS; ENDOTOXEMIA; ESCHERICHIA COLI; HEART SURGERY; HUMAN EXPERIMENT; IMMUNE RESPONSE; INFLAMMATION; NORMAL HUMAN; PRIORITY JOURNAL;

ANTIFIBRINOLYTIC AGENTS; APROTININ; BLOOD CELLS; DESENSITIZATION, IMMUNOLOGIC; ENDOTOXINS; EXTRACORPOREAL CIRCULATION; HUMANS; INTERLEUKIN-10; INTERLEUKIN-6; INTERLEUKIN-8; REFERENCE VALUES; SERINE PROTEINASE INHIBITORS; TIME FACTORS; TRANEXAMIC ACID; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0036021886     PISSN: 10530770     EISSN: None     Source Type: Journal    
DOI: 10.1053/jcan.2002.125145     Document Type: Article

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