Synthesis and benzodiazepine receptor binding activity of 2,9-disubstituted quinolino[2′,3′-5,4](3-pyrazolino)[3,2-b]purin-4-ones

Archiv der Pharmazie

Volumn 335, Issue 5, 2002, Pages 207-212

  El Sayed, Ola A ^a   Habib, Nargues S ^a   Aboul Enein, Hassan Y ^b   Costa, Barbara ^c   Lucacchini, Antonio ^c   Martini, Claudia ^c  

^a Alexandria University Faculty of Pharmacy   (Egypt)

^b KING FAISAL SPECIALIST HOSPITAL AND RESEARCH CENTER   (Saudi Arabia)

^c Department of Psychiatry Neurobiology Pharmacology and Biotechnology ^*  (Italy)

Author keywords

Benzodiazepine receptor binding; Quinolino 2 ,3 5,4 (3 pyrazolino)pyrimidines or purines, synthesis

Indexed keywords

2 METHYL 9 METHOXYQUINOLINO[2',3'-5,4](3 PYRAZOLINO)[3,2 B]PURIN 4 ONE; 9 METHOXY 2 (2 THIENYL)QUINOLINO[2',3'-5,4](3 PYRAZOLINO) [3,2 B]PURIN 4 ONE; 9 METHOXY 2 PHENYLQUINOLINO[2',3'-5,4](3 PYRAZOLINO)[3,2 B]PURIN 4 ONE; 9 METHYL 2 (2 THIENYL)QUINOLINO[2',3'-5,4](3 PYRAZOLINO)[3,2 B]PURIN 4 ONE; BENZODIAZEPINE RECEPTOR; BENZODIAZEPINE RECEPTOR AFFECTING AGENT; FLUMAZENIL; QUINOLINO[2',3'-5,4](3 PYRAZOLINO)[3,2 B]PURIN 4 ONE DERIVATIVE; QUINOLINO[2',3'-5,4](3 PYRAZOLINO)PYRIMIDIN 2 ONE DERIVATIVE; UNCLASSIFIED DRUG; 4 AMINOBUTYRIC ACID A RECEPTOR; PURINE DERIVATIVE;

ARTICLE; BINDING AFFINITY; DRUG SCREENING; DRUG SYNTHESIS; LIGAND BINDING; PRIORITY JOURNAL; RECEPTOR BINDING; RECEPTOR INTRINSIC ACTIVITY; ANIMAL; BRAIN; CATTLE; DRUG ANTAGONISM; METABOLISM; PROTEIN BINDING; RADIOASSAY; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANIMAL; BRAIN; CATTLE; PROTEIN BINDING; PURINONES; RADIOLIGAND ASSAY; RECEPTORS, GABA-A; STRUCTURE-ACTIVITY RELATIONSHIP; ANIMALS;

EID: 0036021859     PISSN: 03656233     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4184(200205)335:5<207::AID-ARDP207>3.0.CO;2-5     Document Type: Article

References (11)

1. Ligand interactions at the benzodiazepine receptor