Experience with a once-daily dosing program of aminoglycosides in critically ill patients

Intensive Care Medicine

Volumn 28, Issue 7, 2002, Pages 936-942

  Buijk, S ^a   Mouton, J ^a   Gyssens, I ^a   Verbrugh, H ^a   Bruining, H ^a,b  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b CANISIUS WILHELMINA HOSPITAL   (Netherlands)

Author keywords

Aminoglycosides; Critically ill; Intensive care; Nephrotoxicity; Pharmacokinetics

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; GENTAMICIN; TOBRAMYCIN; ANTIINFECTIVE AGENT; CREATINE;

ADULT; AGED; ANALYTICAL PARAMETERS; ARTICLE; BLOOD SAMPLING; COMPARTMENT MODEL; CONTROLLED STUDY; CREATININE CLEARANCE; CRITICAL ILLNESS; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG MONITORING; FEMALE; GRAM NEGATIVE INFECTION; HEMOFILTRATION; HUMAN; IMMUNOFLUORESCENCE; INCIDENCE; INTENSIVE CARE UNIT; KIDNEY DYSFUNCTION; KIDNEY FUNCTION; MAJOR CLINICAL STUDY; MALE; MAXIMUM ALLOWABLE CONCENTRATION; MINIMUM INHIBITORY CONCENTRATION; NEPHROTOXICITY; NOMOGRAM; PSEUDOMONAS AERUGINOSA; SEPTIC SHOCK; BACTERIAL INFECTION; BLOOD; COMPARATIVE STUDY; DRUG ADMINISTRATION; DRUG EFFECT; INTENSIVE CARE; KIDNEY; METHODOLOGY; MICROBIOLOGY; MIDDLE AGED; NETHERLANDS;

ADULT; AGED; AGED, 80 AND OVER; ANTIBIOTICS, AMINOGLYCOSIDE; BACTERIAL INFECTIONS; COMPARATIVE STUDY; CREATINE; CRITICAL CARE; DRUG ADMINISTRATION SCHEDULE; FEMALE; GENTAMICINS; HUMAN; KIDNEY; MALE; MIDDLE AGE; NETHERLANDS; SHOCK, SEPTIC; TOBRAMYCIN; ANTI-BACTERIAL AGENTS; HUMANS; MIDDLE AGED;

EID: 0036020310     PISSN: 03424642     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00134-002-1313-7     Document Type: Article

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