The tubulin ancester, FtsZ, draughtsman, designer and driving force for bacterial cytokinesis

Journal of Molecular Biology

Volumn 318, Issue 2, 2002, Pages 219-236

  Addinall, Stephen G ^a   Holland, Barry ^b  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITÉ PARIS SACLAY   (France)

Author keywords

Bacterial cytokinesis; Division site selection; FtsZ polymerization; Min oscillation; Z ring

Indexed keywords

BACTERIAL PROTEIN; FTSZ PROTEIN; PROTEIN DRAUGHTSMAN; TUBULIN; UNCLASSIFIED DRUG; CYTOSKELETON PROTEIN; FTSZ PROTEIN, BACTERIA; GUANOSINE TRIPHOSPHATASE; MINC PROTEIN, BACTERIA;

BACTERIAL CELL; CELL CYCLE; CELLULAR DISTRIBUTION; CYTOKINESIS; IMMUNOCYTOCHEMISTRY; MICROTUBULE; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN FUNCTION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; REVIEW; STRUCTURE ANALYSIS; BACTERIAL GENE; BACTERIAL PHENOMENA AND FUNCTIONS; BACTERIUM; CAULOBACTER CRESCENTUS; CELL DIVISION; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; ESCHERICHIA COLI; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; METHANOCOCCUS; PHYSIOLOGY;

BACTERIA (MICROORGANISMS);

BACTERIA; BACTERIAL PHYSIOLOGY; BACTERIAL PROTEINS; CAULOBACTER CRESCENTUS; CELL CYCLE; CELL DIVISION; CYTOSKELETAL PROTEINS; ESCHERICHIA COLI; GENES, BACTERIAL; GTP PHOSPHOHYDROLASES; METHANOCOCCUS; MICROTUBULES; MODELS, MOLECULAR; TUBULIN;

EID: 0036019535     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2836(02)00024-4     Document Type: Review

References (166)

1. Dependency on medium and temperature of cell size and chemical composition during balanced growth of Salmonella typhimurium
2. Cell growth, genome duplication and cell division in Escherichia coli
3. A model for the statistics of the cell division process
4. Chromosome partitioning in Escherichia coli: Novel mutants producing anucleate cells
5. On the bacterial life sequence
6. FtsZ ring structure associated with division in Escherichia coli
7. Regulation of bacterial cell division: Temperature-sensitive mutants of Escherichia coli that are defective in septum formation
8. Use of immunofluorescence to visualize cell-specific gene expression during sporulation in Bacillus subtilis
9. FtsZ from Escherichia coli, Azotobacter vinelandii, and Thermotoga maritima: Quantitation, GTP hydrolysis, and assembly
10. Division genes in Escherichia coli are expressed coordinately to cell septum requirements by gearbox promoters
11. ftsZ is an essential cell division gene in Escherichia coli
12. Dependency of Escherichia coli cell-division size, and independency of nucleoid segregation on the mode and level of ftsZ expression
13. Regulation of the expression of the cell-cycle gene ftsZ by DicF antisense RNA. Division does not require a fixed number of FtsZ molecules
14. Overproduction of FtsZ induces minicell formation in E. coli
15. Metabolic alarms and cell division in Escherichia coli
16. The cell cycle of Escherichia coli
17. Inhibition of cell division initiation by an imbalance in the ratio of FtsA to FtsZ
18. The proper ratio of FtsZ to FtsA is required for cell division to occur in Escherichia coli
19. Regulation of the synthesis of surface protein in the cell cycle of E. coli B/r
20. Transcription of ftsZ oscillates during the cell cycle of Escherichia coli
21. Relationship between ftsZ gene expression and chromosome replication in Escherichia coli
22. Control of cell division in Escherichia coli: Regulation of transcription of ftsQA involves both rpoS and SdiA-mediated autoinduction
23. The ftsQ1p gearbox promoter of Escherichia coli is a major sigma S-dependent promoter in the ddlB-ftsA region
24. Intracellular 5′,5′-dinucleoside polyphosphate levels remain constant during the Escherichia coli cell cycle
25. The intracellular concentration of cyclic adenosine 3′,5′-monophosphate is constant throughout the cell cycle of Escherichia coli
26. Relationship between cellular diadenosine 5′,5‴-P1,P4-tetraphosphate level, cell density, cell growth stimulation and toxic stresses
27. Signal transduction mechanisms in Caulobacter crescentus development and cell cycle control
28. Cell cycle-dependent transcriptional and proteolytic regulation of FtsZ in Caulobacter
29. Cell cycle and positional constraints on FtsZ localization and the initiation of cell division in Caulobacter crescentus
30. FtsZ-spirals and -arcs determine the shape of the invaginating septa in some mutants of Escherichia coli
31. FtsZ dynamics during the division cycle of live Escherichia coli cells
32. Temperature shift experiments with an ftsZ84(Ts) strain reveal rapid dynamics of FtsZ localization and indicate that the Z ring is required throughout septation and cannot reoccupy division sites once constriction has initiated
33. Timing of FtsZ assembly in Escherichia coli
34. Cell division inhibitors SulA and MinC/MinD block septum formation at different steps in the assembly of the Escherichia coli division machinery
35. Magnesium-induced linear self-association of the FtsZ bacterial cell division protein monomer. The primary steps for FtsZ assembly
36. Regulation of polar cap formation in the life cycle of Escherichia coli
37. Morphogenesis of Escherichia coli
38. Rate and topography of peptidoglycan synthesis during cell division in Escherichia coli: Concept of a leading edge
39. Cell length, cell growth and cell division
40. Timing of synthetic activities in the cell cycle
41. Chromosome replication, transcription and control of cell division in Escherichia coli
42. The Escherichia coli cell cycle: One cycle or multiple independent processes that are co-ordinated?
43. Transcription of essential cell division genes is linked to chromosome replication in Escherichia coli
44. A mutant cysteinyl-tRNA synthetase affecting timing of chromosomal replication initiation in B. subtilis and conferring resistance to a protein kinase C inhibitor
45. Identification and characterization of a negative regulator of FtsZ ring formation in Bacillus subtilis
46. Protein degradation in Escherichia coli: The lon gene controls the stability of sulA protein
47. Role of the SulB (FtsZ) protein in division inhibition during the SOS response in Escherichia coli: FtsZ stabilizes the inhibitor SulA in maxicells
48. Effect of suppressors of SOS-mediated filamentation on sfiA operon expression in Escherichia coli
49. Mutagenesis and more: UmuDC and the Escherichia coli SOS response
50. Two pathways of division inhibition in UV-irradiated E. coli
51. Interaction between FtsZ and inhibitors of cell division
52. A cell division inhibitor SulA of Escherichia coli directly interacts with FtsZ through GTP hydrolysis
53. Inhibition of FtsZ polymerization by SulA, an inhibitor of septation in Escherichia coli
54. Bacterial SOS checkpoint protein SulA inhibits polymerization of purified FtsZ cell division protein
55. A division inhibitor and a topological specificity factor coded for by the minicell locus determine proper placement of the division septum in E. coli
56. The MinC component of the division site selection system in Escherichia coli interacts with FtsZ to prevent polymerization
57. Crystal structure of the bacterial cell division inhibitor MinC
58. Escherichia coli division inhibitor MinCD blocks septation by preventing Z ring formation
59. Novel mechanism of cell division inhibition associated with the SOS response in Escherichia coli
60. Minicell-forming mutants of Escherichia coli: Suppression of both DicB- and MinD-dependent division inhibition by inactivation of the minC gene product
61. Size variations and correlation of different cell cycle events in slow-growing Escherichia coli
62. On the precision and accuracy achieved by Escherichia coli cells at fission about their middle
63. FtsZ ring clusters in min and partition mutants: Role of both the Min system and the nucleoid in regulating FtsZ ring localization
64. Role of the nucleoid in the toporegulation of division
65. Cell shape and division in E. coli
66. Nucleoid-independent identification of cell division sites in Escherichia coli
67. Themes and variations in prokaryotic cell division
68. Bacterial cell division: Regulating Z ring formation
69. Midcell Z ring assembly in the absence of entry into the elongation phase of the round of replication in bacteria: Coordinating chromosome replication with cell division
70. Movement of replicating DNA through a stationary replisome
71. An analysis of the factory model for chromosome replication and segregation in bacteria
72. Dynamic localization cycle of the cell division regulator MinE in Escherichia coli
73. The MinE ring required for proper placement of the division site is a mobile structure that changes its cellular location during the Escherichia coli division cycle
74. Membrane redistribution of the Escherichia coli MinD protein induced by MinE
75. The MinD protein is a membrane ATPase required for the correct placement of the Escherichia coli division site
76. Proper placement of the Escherichia coli division site requires two functions that are associated with different domains of the MinE protein
77. Structural and functional studies of MinD ATPase: Implications for the molecular recognition of the bacterial cell division apparatus
78. Crystal structure of the bacterial cell division regulator MinD
79. Structural basis for the topological specificity function of minE
80. Control of cell shape in bacteria: Helical, actin-like filaments in Bacillus subtilis
81. Prokaryotic origin of the actin cytoskeleton
82. Topological regulation of cell division in E. coli spatiotemporal oscillation of MinD requires stimulation of its ATPase by MinE and phospholipid
83. MinDE-dependent pole-to-pole oscillation of division inhibitor MinC in Escherichia coli
84. ZipA-induced bundling of FtsZ polymers mediated by an interaction between C-terminal domains
85. FtsZ and organelle division in Protists
86. Mitochondrial FtsZ in a chromophyte alga
87. Quantal behavior of a diffusible factor which initiates septum formation at potential division sites in Escherichia coli
88. Cell division in Escherichia coli minB mutants
89. Coordinating DNA replication with cell division: Lessons from outgrowing spores
90. Cell cycle-dependent duplication and bidirectional migration of SeqA-associated DNA-protein complexes in E. coli
91. Selection of the midcell division site in Bacillus subtilis through MinD-dependent polar localization and activation of MinC
92. Phospholipid domains determine the spatial organization of the Escherichia coli cell cycle: The membrane tectonics model
93. Visualization of membrane domains in Escherichia coli
94. Visualization of phospholipid domains in Escherichia coli by using the cardiolipin-specific fluorescent dye 10-N-nonyl acridine orange
95. Hypothesis: Membrane domains and hyperstructures control bacterial division
96. Isolation and characterization of ftsZ alleles that affect septal morphology
97. Bacterial cell division: The cycle of the ring
98. Genetic analysis of the E. coli division clock
99. Cell division and peptidoglycan assembly in Escherichia coli
100. Recruitment of ZipA to the septal ring of Escherichia coli is dependent on FtsZ and independent of FtsA
101. Two polypeptide products of the Escherichia coli cell division gene ftsW and a possible role for FtsW in FtsZ function
102. Crystal structure of the cell division protein FtsA from Thermotoga maritima
103. Isolation and characterization of dcw cluster from Streptomyces collinus producing kirromycin
104. Slow polymerization of Mycobacterium tuberculosis FtsZ
105. Escherichia coli cell-division gene ftsZ encodes a novel GTP-binding protein
106. The essential bacterial cell-division protein FtsZ is a GTPase
107. Escherichia coli cell division protein FtsZ is a guanine nucleotide binding protein
108. The FtsZ protein of Bacillus subtilis is localized at the division site and has GTPase activity that is dependent upon FtsZ concentration
109. FtsZ ring: The eubacterial division apparatus conserved in archae-bacteria
110. Site-specific mutations of FtsZ: Effects on GTPase and in vitro assembly
111. FtsZ ring in bacterial cytokinesis
112. Self-activation of guanosine triphosphatase activity by oligomerization of the bacterial cell division protein FtsZ
113. Polymerization of FtsZ, a bacterial homolog of tubulin: Is assembly cooperative?
114. Analysis of FtsZ assembly by light scattering and determination of the role of divalent metal cations
115. Guanine nucleotide-dependent PROOF assembly of FtsZ into filaments
116. GTP-dependent polymerization of Escherichia coli FtsZ protein to form tubules
117. Bacterial cell division protein FtsZ assembles into protofilament sheets and mini-rings, structural homologs of tubulin polymers
118. Ca2+-mediated GTP-dependent dynamic assembly of bacterial cell division protein FtsZ into asters and polymer networks in vitro
119. Tubulin-like protofilaments in Ca2+-induced FtsZ sheets
120. FtsZ, a prokaryotic homolog of tubulin?
121. Helical tubes of FtsZ from Methanococcus jannaschii
122. Straight and curved conformations of FtsZ are regulated by GTP hydrolysis
123. Dynamic assembly of FtsZ regulated by GTP hydrolysis
124. Zur feinstruktur des plastidenstromas von Hordeum vulgare L
125. Observations of microtubule-like structures within spinach plastids
126. Novel filaments 5 nm in diameter constitute the cytosolic ring of the plastid division apparatus
127. FtsZ ring formation in fts mutants
128. The FtsZ protofilament and attachment of ZipA: Structural constraints on the FtsZ power stroke
129. Slow changes in cytosolic free Ca2+ in Escherichia coli highlight two putative influx mechanisms in response to changes in extracellular calcium
130. An assessment of the role of intracellular free Ca2+ in E. coli
131. Escherichia coli FtsZ polymers contain mostly GTP and have a high nucleotide turnover
132. The polymerization mechanism of the bacterial cell division protein FtsZ
133. Force generation by microtubule assembly/disassembly in mitosis and related movements
134. The polymerization motor
135. Crystal structure of the bacterial cell-division protein FtsZ
136. Structure of the alpha beta tubulin dimer by electron crystallography
137. Atomic structures of tubulin and FtsZ
138. Genetic analysis of the Escherichia coli FtsZ·ZipA interaction in the yeast two-hybrid system: Characterization of FtsZ residues essential for the interactions with ZipA and with FtsA
139. Genetic and functional analyses of the conserved C-terminal core domain of Escherichia coli FtsZ
140. A conserved residue at the extreme C terminus of FtsZ is critical for the FtsA-FtsZ interaction in Staphylococcus aureus
141. Cytological and biochemical characterization of the FtsA cell division protein of Bacillus subtilis
142. Direct binding of FtsZ to ZipA, an essential component of the septal ring structure that mediates cell division in E. coli
143. A factor that positively regulates cell division by activating transcription of the major cluster of essential cell division genes of Escherichia coli
144. Aberrant cell division and random FtsZ ring positioning in Escherichia coli cpxA* mutants
145. Fusidic acid-resistant EF-G perturbs the accumulation of ppGpp
146. Regulation of Escherichia coli cell division genes ftsA and ftsZ by the two-component system rcsC-rcsB
147. ZipA is a MAP-Tau homolog and is essential for structural integrity of the cytokinetic FtsZ ring during bacterial cell division
148. Diadenosine 5′,5‴-P1,P4-tetraphosphate (Ap4A) controls the timing of cell division in Escherichia coli
149. The essential two-component regulatory system encoded by yycF and yycG modulates expression of the ftsAZ operon in Bacillus subtilis
150. Lack of S-adenosylmethionine results in a cell division defect in Escherichia coli
151. The Bacillus subtilis DivIVA protein targets to the division septum and controls the site specificity of cell division
152. A single base change in the acceptor stem of tRNA(3Leu) confers resistance upon Escherichia coli to the calmodulin inhibitor, 48/80
153. Characterization of an Escherichia coli mutant, feeA, displaying resistance to the calmodulin inhibitor 48/80 and reduced expression of the rare tRNA3Leu
154. Novel temperature-sensitive mutants of Escherichia coli that are unable to grow in the absence of wild-type tRNA6Leu
155. Effects of calcium and calcium chelators on growth and morphology of Escherichia coli L-form NC-7
156. The E. coli divE mutation, which differentially inhibits synthesis of certain proteins, is in tRNASer1
157. The Escherichia coli cell division mutation ftsM1 is in serU
158. Localization and function of early cell division proteins in filamentous Escherichia coli cells lacking phosphatidylethanolamine
159. The E. coli dnaY gene encodes an arginine transfer RNA
160. The timing of cell division: Ap4A as a signal
161. The Escherichia coli flagellar transcriptional activator flhD regulates cell division through induction of the acid response gene cadA
162. Acetyl phosphate and the phosphorylation of OmpR are involved in the regulation of the cell division rate in Escherichia coli
163. CedA is a novel Escherichia coli protein that activates the cell division inhibited by chromosomal DNA over-replication
164. Mutation in the structural gene for release factor 1 (RF-1) of Salmonella typhimurium inhibits cell division
165. Resistance to trifluoroperazine, a calmodulin inhibitor, maps to the fabD locus in Escherichia coli