Expression of G1 phase cyclins in human gastric cancer and gastric mucosa of first-degree relatives

Digestive Diseases and Sciences

Volumn 47, Issue 6, 2002, Pages 1248-1256

  Miehlke, Stephan ^a   Yu, Jun ^a   Ebert, Matthias ^b   Szokodi, Daniel ^a   Vieth, Michael ^c   Kuhlisch, Eberhard ^a   Buchcik, Rene ^d   Schimmin, Wolfgang ^e   Wehrmann, Ursula ^a   Malfertheiner, Peter ^b   Ehninger, Gerhard ^a   Bayerdörffer, Ekkehard ^a   Stolte, Manfred ^c  

^a UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

^b OTTO VON GUERICKE UNIVERSITY   (Germany)

^c INSTITUTE OF PATHOLOGY   (Germany)

^d DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^e Department of Gastroenterology   (Germany)

Author keywords

Cyclins; Gastric cancer; Gastritis; Helicobacter pylori; Intestinal metaplasia

Indexed keywords

CYCLIN D1; CYCLIN D2; CYCLIN D3; CYCLIN E;

ADULT; AGED; ARTICLE; CANCER PATIENT; CELL CYCLE G1 PHASE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; FAMILY STUDY; FEMALE; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HIGH RISK POPULATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTESTINE METAPLASIA; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RELATIVE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH ANTRUM; STOMACH CARCINOGENESIS; STOMACH CARCINOMA; STOMACH MUCOSA; GENETICS; METABOLISM; MIDDLE AGED; PHYSIOLOGY; STOMACH TUMOR;

AGED; AGED, 80 AND OVER; CYCLIN D1; CYCLIN E; FEMALE; G1 PHASE; GASTRIC MUCOSA; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; STOMACH NEOPLASMS;

EID: 0036016536     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1015358127751     Document Type: Article

References (48)

1. Mortality by cause for eight regions of the world: Global burden of disease study
2. Cancer of the stomach: A patient care study by the American College of Surgeons
3. Gastric carcinoma: Clinical, pathogenic and molecular aspects
4. Familial occurrence of gastric cancer in the 2-year experience of a population-based registry
5. Family history and the risk of stomach and colorectal cancer
6. Chronic gastritis profiles in sibs of probands calculated to carry a highly increased risk of gastric carcinoma
7. Gastric cancer in San Marinese and their first degree relatives in San Marino and the United States. Gastroscopic biopsy as an epidemiological tool
8. Helicobacter pylori gastritis and intestinal metaplasia in a gastric cancer family
9. Helicobacter pylori gastritis of the gastric cancer phenotype in relatives of gastric carcinoma patients
10. Increased cell proliferation of the gastric mucosa in first-degree relatives of gastric carcinoma patients
11. Frequency of TPR-MET rearrangement in patients with gastric carcinoma and in first-degree relatives
12. Alpha-catenin expression is decreased in human gastric cancers and in the gastric mucosa of first degree relatives
13. Expression of metallothioenin II in intestinal metaplasia, dysplasia, and gastric cancer
14. Expression of transforming growth factor beta-1 in gastric cancer and in the gastric mucosa of first-degree relatives of patients with gastric cancer
15. 1 cyclin (Cln) function in yeast
16. Genomic organization, chromosomal localization, and independent expression of human cyclin D genes
17. Cancer cell cycles
18. Molecular biological observations in gastric cancer
19. Overexpression of cyclin D1 enhances gene amplification
20. Aberrant expression of cyclin D2 is an early event in human male germ cell tumorigenesis
21. 1/S transition and high abundance in quiescent tissue suggest a dual role in proliferation and differentiation
22. Human cyclin E, a new cyclin that interacts with two members of the CDC 2 gene family
23. Quantitative analysis of the cyclin expression in human esophageal cancer cell lines
24. Overexpression and localization of cyclin D1 mRNA and antigen in esophageal cancer
25. Overexpression of cyclin D1 in human pancreatic carcinoma is associated with poor prognosis
26. Increased cyclin D1 in human pancreatic cancer is associated with decreased postoperative survival
27. Expression of cyclins D1 and E in human colon adenocarcinoma
28. Amplification of cyclin genes in colorectal carcinomas
29. Cyclin D3 expression, cell proliferation and pathological stage of human primary colorectal cancer
30. Frequent amplification of the cyclin E gene in human gastric carcinomas
31. Expression of cyclin D1 and cyclin E in human gastric carcinoma and its clinicopathologic significance
32. Expression of cyclin E in human gastric adenomas and adenocarcinomas: Correlation with proliferative activity and p 53 status
33. Mutation frequency of the p16/CDKN 2 gene and amplification of the cyclin E gene in human primary gastric carcinomas
34. Cyclin D2 overexpression and lack of p27 correlate positively and cyclin E inversely with a poor prognosis in gastric cancer cases
35. Classification and grading of gastritis. The updated Sydney System
36. The two main histological types of gastric carcinoma: Diffuse and so-called intestinal type carcinoma. An attempt at a histo-clinical classification
37. Use of semiquantitative reverse transcription-polymerase chain reaction to study gene expression in normal human skin fibroblasts following low dose-rate irradiation
38. The 5D4 antibody (anti-cyclin D1/D2) related antigen: Cytoplasmic staining is correlated to the progression of gastric cancer
39. Clinicopathologic study of PRAD1/cyclin D1 overexpressing lymphoma with special reference to mantle cell lymphoma. A distinct molecular pathologic entity
40. Expression of cyclin D1 and EMS1 in bladder tumours: Relationship with chromosome 11q13 amplification
41. Cyclin D1 and Cyclin E expression in malignant thyroid cells and in human thyroid carcinomas
42. Overexpression of cyclin D2 in chronic B-cell malignancies
43. Cyclin D1 and D3 are associated with the SCF complex and are coordinately elevated in breast cancer
44. A human model of gastric carcinogenesis
45. Increased prevalence of precancerous changes in relatives of gastric cancer patients: Critical role of H. pylori
46. Interleukin-1 polymorphisms associated with increased risk of gastric cancer
47. 1 to S transition in AGS epithelial cells