Gender and hormonal status affect the regulation of hepatic cholesterol 7α-hydroxylase activity and mRNA abundance by dietary soluble fiber in the guinea pig

Atherosclerosis

Volumn 163, Issue 1, 2002, Pages 29-37

  Roy, Suheeta ^a   Freake, Hedley C ^a   Fernandez, Maria Luz ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

Author keywords

Cholesterol 7 hydroxylase; Dietary fiber; Gender; LDL cholesterol; Liver; Menopause

Indexed keywords

CHOLESTEROL 7ALPHA MONOOXYGENASE; ISPAGULA; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MESSENGER RNA; PECTIN; TRIACYLGLYCEROL; ESTROGEN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL METABOLISM; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIET; DIETARY FIBER; DIETARY INTAKE; ENZYME ACTIVITY; ENZYME REGULATION; FEMALE; GENDER; GUINEA PIG; HORMONE DETERMINATION; HYPOCHOLESTEROLEMIA; LIPID ANALYSIS; MALE; MENOPAUSE; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA ANALYSIS; SEX DIFFERENCE; TRIACYLGLYCEROL BLOOD LEVEL; ANALYSIS OF VARIANCE; ANIMAL; COMPARATIVE STUDY; DISEASE MODEL; ENZYMOLOGY; HUMAN; LIVER; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PROBABILITY; RAT; REFERENCE VALUE; SEX; SOLUBILITY; SPECIES DIFFERENCE;

ANALYSIS OF VARIANCE; ANIMAL; BASE SEQUENCE; CHOLESTEROL 7-ALPHA-HYDROXYLASE; COMPARATIVE STUDY; DIETARY FIBER; DISEASE MODELS, ANIMAL; ESTROGENS; FEMALE; GUINEA PIGS; HUMAN; LIPOPROTEINS, LDL CHOLESTEROL; LIVER; MALE; MOLECULAR SEQUENCE DATA; OVARIECTOMY; POLYMERASE CHAIN REACTION; PROBABILITY; RATS; REFERENCE VALUES; RNA, MESSENGER; SEX; SOLUBILITY; SPECIES SPECIFICITY; SUPPORT, U.S. GOV'T, NON-P.H.S.; ANIMALS; CHOLESTEROL, LDL; HUMANS;

EID: 0036015981     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9150(01)00749-3     Document Type: Article

References (31)

1. Cholesterol-lowering effects of dietary fiber: A meta-analysis
2. Whole-grain consumption and risk of coronary heart disease: Results from the Nurses' Health Study
3. Whole-grain intake may reduce the risk of ischemic heart disease death in postmenopausal women: The Iowa Women's Health Study
4. The Oxford vegetarian study: An overview
5. Dietary, antioxidant vitamins and fiber in the etiology of cardiovascular disease and all-causes mortality: Results from the Scottish Heart Health Study
6. Fiber, inulin and oligofructose: Similarities and differences
7. Cholesterol lowering action of psyllium mucilloid in the hamster: Sites and possible mechanisms of action
8. Distinct mechanisms of plasma LDL lowering by dietary fiber in the guinea pig: Specific effects of pectin, guar gum and psyllium
9. Hamsters and guinea pigs differ in their plasma lipoprotein cholesterol distribution when fed diets varying in animal protein, soluble fiber or cholesterol content
10. Molecular cloning and sequence analysis of cDNA encoding human cholesterol 7α-hydroxylase
11. Feedback regulation of hepatic 7α-hydroxylase expression by bile salts in the hamster
12. Gender and hormonal status affect the hypolipidemic mechanisms of dietary soluble fiber in guinea pigs
13. Regulation of hepatic 7α-hydroxylase expression by dietary psyllium in the hamster
14. Gender differences in response to dietary soluble fiber in guinea pigs: Effects of pectin, guar gum and psyllium
15. Hypocholesterolemic actions of atorvastatin are associated with alterations on hepatic cholesterol metabolism and lipoprotein composition in the guinea pig
16. Circadian rhythms of sterol 12 alpha-hydroxylase, cholesterol 7 alpha-hydroxylase and DBP involved in rat cholesterol catabolism
17. Enzymatic determination of total serum cholesterol
18. Enzymatic determination of triglycerides, free cholesterol and cholesterol in tissue lipid extracts
19. Carbohydrate-fat exchange and regulation of hepatic cholesterol and plasma lipoprotein metabolism in the guinea pig
20. A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples
21. Cloning and regulation of cholesterol 7α-hydroxylase, the rate-limiting enzyme in bile acid biosynthesis
22. Hepatic expression of genes regulation lipid metabolism in rabbits
23. Regulation of cholesterol 7α-hydroxylase in the liver: Cloning, sequencing and regulation of cholesterol 7α-hydroxylase mRNA
24. Transcription of the rat and mouse proenkephalin genes is initiated at distinct sites in spermatogenic and somatic cells
25. Coronary heart disease in relation to age, sex and the menopause
26. Menopause-related changes in lipoproteins and some other cardiovascular risk factors
27. Effect of monounsaturated fatty acids versus complex carbohydrates on high density lipoprotein in healthy men and women
28. Increased fecal bile acid excretion and changes in the circulating bile acid pool are involved in the hypocholesterolemic and gallstone-preventive actions of psyllium in hamsters
29. Lime-treated corn husks lower plasma LDL cholesterol in guinea pigs by altering hepatic cholesterol metabolism
30. Citrus pectin and cholesterol interact to regulate hepatic cholesterol homeostasis and lipoprotein metabolism: A dose-response study in guinea pigs
31. Regulation of hepatic 7α-hydroxylase and response to dietary cholesterol in the rat and hamster