A novel system applying the 2-deoxyglucose method to fish for characterization of environmental neurotoxins

Toxicology Mechanisms and Methods

Volumn 12, Issue 1, 2002, Pages 35-43

  Choich, J A ^a   Sass, J B ^a   Silbergeld, Ellen K ^a  

^a UNIVERSITY OF MARYLAND   (United States)

Author keywords

Environment; Fish; Glucose; Metabolism; Neurobiology; Neurotoxins

Indexed keywords

CARBON 14; DEOXYGLUCOSE; EXCITOTOXIN; GLUCOSE; N METHYL DEXTRO ASPARTIC ACID; NEUROTOXIN;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CENTRAL NERVOUS SYSTEM; CEREBELLUM; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ECOTOXICITY; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL MONITORING; FISH; GLUCOSE METABOLISM; MEASUREMENT; NONHUMAN; OPTIC TECTUM; PRIORITY JOURNAL; TELENCEPHALON; TILAPIA; TOXIN ANALYSIS;

ANIMALIA; TILAPIA;

EID: 0036013096     PISSN: 15376516     EISSN: 15376524     Source Type: Journal    
DOI: 10.1080/15376510209167934     Document Type: Article

References (5)

1. El-Nabawi, A., Queensberry, M., Saito, K., Silbergeld, E. K., Vasta, G., and Eldefrawi, A. 2000. The N-methyl-D-aspartate neurotransmitter receptor mammalian brain target for the dinoflagellate Pfiesteria piscicida toxin. Toxicol. Appl. Pharmacol. November 15, 2000.
2. Linn, C. L., and Gafka, A. C. Activation of metabotropic glutamate receptors modulates the voltagegated sustained calcium current in a teleost horizontal cell. J. Neurophysiol 81:425-434.
3. 14C deoxyglucose method for the measurement of local cerebral glucose utilization: Theory, procedure, and normal values in the conscious and anesthetized rat. J. Neurochem. 28:897-916.
4. Tong, C. K., Pan, M. P., and Chang, Y. C. 1992. Characterization of L-glutamate and kainate binding sites in the brain of a freshwater fish. Telapilia monsanbica [sic]. Neuroscience 49:237-246.
5. Wulliman, M. F., Rupp, B., and Reichert, H. 1996. Neuroanatomy of the Zebrafish Brain: A Topological Atlas. Basel, Switzerland: Birkhauser Verlag.