Dean vortex membrane microfiltration and diafiltration of rBDNF E. coli inclusion bodies

Biotechnology Progress

Volumn 18, Issue 2, 2002, Pages 322-329

  Schutyser, Maarten ^a,c   Rupp, Randall ^b   Wideman, Janusz ^b   Belfort, Georges ^a  

^a Rensselaer Polytechnic Institute   (United States)

^b REGENERON PHARMACEUTICALS INC   (United States)

^c WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; POLYSORBATE; RECOMBINANT PROTEIN;

ARTICLE; ARTIFICIAL MEMBRANE; CELL INCLUSION; CENTRIFUGATION; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; EQUIPMENT DESIGN; ESCHERICHIA COLI; FILTRATION; FLOW KINETICS; INSTRUMENTATION; ISOLATION AND PURIFICATION; METHODOLOGY; MICROPORE FILTER; PERMEABILITY; PRESSURE; SENSITIVITY AND SPECIFICITY;

BRAIN-DERIVED NEUROTROPHIC FACTOR; CENTRIFUGATION; EQUIPMENT DESIGN; ESCHERICHIA COLI; FILTRATION; INCLUSION BODIES; MEMBRANES, ARTIFICIAL; MICROPORE FILTERS; MODELS, MOLECULAR; PERMEABILITY; POLYSORBATES; PRESSURE; RECOMBINANT PROTEINS; RHEOLOGY; SENSITIVITY AND SPECIFICITY;

CROSS-FLOW MICROFILTRATION (CMF);

INCLUSIONS; MICROFILTRATION; SURFACE ACTIVE AGENTS; SUSPENSIONS (FLUIDS); VORTEX FLOW;

ESCHERICHIA COLI;

ESCHERICHIA COLI;

EID: 0036010284     PISSN: 87567938     EISSN: None     Source Type: Journal    
DOI: 10.1021/bp010180w     Document Type: Article

References (27)

1. Recombinant human brain-derived neutrophic factor (rHuDNF)
2. Interaction of proteins with polymeric synthetic membranes
3. Dean vortices with wall flux in a curved channel membrane system. 6. Two-dimensional magnetic resonance imaging of the velocity field in a curved impermeable slit
4. Fluid motion in a curved channel
5. Comparison of ultra- and microfiltration in the presence and absence of secondary flow with polysaccharides, proteins and yeast suspensions
6. Flux enhancement due to secondary flow in a helical tubular module: 14 Ultra and microfiltration of polysaccharides, proteins and yeast suspensions
7. Hollow-fibre membrane module design: Comparison of different curved geometries with Dean vortices
8. Synthetic membranes in biotechnology: Realities and possibilities
9. Neutrophic factors: From structure-function studies to designing effective therapeutics
10. Protein transmission during Dean vortex microfiltration of yeast suspensions
11. Improved filtration of microbial suspensions
12. A new coliled hollow fiber design for enhanced microfiltration performance in biotechnology
13. A new coiled hollow fiber module design for enhanced microfiltration performance
14. Membrane surface modification and backpulsing for waste-water treatment
15. Microfiltration of yeast suspensions with self-cleaning spiral vortices: Possibilities for a new membrane module design
16. Flux enhancement during Dean vortex membrane nanofiltration: 10. Design, construction and system characterization
17. Magnetic resonance flow imaging and numerical analysis of curved tube flow: 16. Effect of curvature and flow rate on Dean vortex stability and bifurcation
18. Calculation of the hydrodynamic permeability of gels and gel-filled microporous membranes
19. Visualization of Taylor-Couettead spiral Poiseuille flows using a snapshot FLASH spatial tagging sequence
20. Increasing membrane permeability of UV-modified poly(ether sulfone) ultrafiltration membranes
21. Structure of the brain-derived neutrophic factor/neutrophin 3 heterodimer
22. Filtration behaviors of rod-shaped bacterial broths in unsteady-state phase of cross-flow filtration
23. Enhanced performance for pressure-driven membrane processes: The argument for fluid instabilities
24. High performance tangential flow filtration