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Volumn 10, Issue 6, 2002, Pages 2067-2076
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Synthesis and in vitro antitumor activity of thiophene analogues of 5-chloro-5,8-dideazafolic acid and 2-methyl-2-desamino-5-chloro-5,8-dideazafolic acid
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Author keywords
[No Author keywords available]
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Indexed keywords
2 AMINO 5 CHLORO 3,4 DIHYDRO 6 METHYL 4 OXOQUINAZOLINE;
2 METHYL 2 DESAMINO 5 CHLORO 5,8 DIDEAZAFOLIC ACID;
2,6 DIMETHYL 5 CHLORO 3,4 DIHYDROQUINAZOLIN 4 ONE;
2,6 DIMETHYL 5 CHLOROBENZ[1,3 D]OXAZIN 4 ONE;
4 CHLORO 5 METHYLISATIN;
5 CHLORO 5,7 DIDEAZAFOLIC ACID;
ACETIC ANHYDRIDE;
AMMONIA;
ANTINEOPLASTIC AGENT;
CHLOROBENZOIC ACID DERIVATIVE;
ESTER;
GLUTAMIC ACID;
KETONE DERIVATIVE;
METHYL 2 AMINO 5 METHYL 6 CHLOROBENZOATE;
METHYL GROUP;
N [5 [N (2 AMINO 5 CHLORO 3,4 DIHYDRO 4 OXOQUINAZOLIN 6 YL)METHYLAMINO] 2 THENOYL]GLUTAMIC ACID;
N [5 [N (5 CHLORO 3,4 DIHYDRO 2 METHYL 4 OXOQUINAZOLIN 6 YL)METHYLAMINO] 2 THENOYL]GLUTAMIC ACID;
QUINAZOLINE DERIVATIVE;
SODIUM HYDROXIDE;
TERT BUTYL N (5 AMINO 2 THENOYL)GLUTAMIC ACID;
THIOPHENE DERIVATIVE;
UNCLASSIFIED DRUG;
DRUG DERIVATIVE;
FOLIC ACID;
FOLIC ACID ANTAGONIST;
ANTINEOPLASTIC ACTIVITY;
ARTICLE;
BROMINATION;
CANCER INHIBITION;
CONTROLLED STUDY;
DRUG EFFECT;
DRUG SYNTHESIS;
HUMAN;
HUMAN CELL;
IC 50;
IN VITRO STUDY;
LEUKEMIA CELL;
LYMPHOBLAST;
POLYMERIZATION;
TUMOR CELL CULTURE;
CELL CULTURE;
CELL DIVISION;
CHEMICAL STRUCTURE;
CHEMISTRY;
INFRARED SPECTROPHOTOMETRY;
LYMPHATIC LEUKEMIA;
PATHOLOGY;
STRUCTURE ACTIVITY RELATION;
SYNTHESIS;
ANTINEOPLASTIC AGENTS;
CELL DIVISION;
FOLIC ACID;
FOLIC ACID ANTAGONISTS;
HUMANS;
INHIBITORY CONCENTRATION 50;
LEUKEMIA, LYMPHOCYTIC;
MOLECULAR STRUCTURE;
SPECTROPHOTOMETRY, INFRARED;
STRUCTURE-ACTIVITY RELATIONSHIP;
THIOPHENES;
TUMOR CELLS, CULTURED;
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EID: 0036009904
PISSN: 09680896
EISSN: None
Source Type: Journal
DOI: 10.1016/S0968-0896(02)00018-4 Document Type: Article |
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Times cited : (25)
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References (34)
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