|
|
Volumn 10, Issue 6, 2002, Pages 1979-1989
|
|
Analysis of stereoelectronic properties, mechanism of action and pharmacophore of synthetic indolo[2,1-b]quinazoline-6,12-dione derivatives in relation to antileishmanial activity using quantum chemical, cyclic voltammetry and 3-D-QSAR CATALYST procedures
a
|
|
Author keywords
[No Author keywords available]
|
|
Indexed keywords
INDOLO[2,1 B]QUINAZOLINE 6,12 DIONE;
QUINAZOLINE DERIVATIVE;
UNCLASSIFIED DRUG;
ANTIPROTOZOAL AGENT;
AMASTIGOTE;
ANIMAL CELL;
ANTIBACTERIAL ACTIVITY;
ARTICLE;
CALCULATION;
CONCENTRATION RESPONSE;
CONTROLLED STUDY;
CORRELATION FUNCTION;
CYCLIC POTENTIOMETRY;
DENSITY;
DIAGNOSTIC PROCEDURE;
DRUG MECHANISM;
DRUG SYNTHESIS;
ELECTRON TRANSPORT;
IN VITRO STUDY;
LEISHMANIA DONOVANI;
MACROPHAGE;
MOUSE;
NONHUMAN;
PHARMACOPHORE;
QUALITATIVE ANALYSIS;
QUANTITATIVE ANALYSIS;
QUANTUM THEORY;
RAT;
STRUCTURE ACTIVITY RELATION;
TOXICITY;
VALIDATION PROCESS;
ANIMAL;
CELL LINE;
CHEMICAL STRUCTURE;
CHEMISTRY;
COMPUTER PROGRAM;
COMPUTER SIMULATION;
CONFORMATION;
DRUG EFFECT;
ELECTROCHEMISTRY;
IC 50;
NERVE CELL;
QUANTITATIVE STRUCTURE ACTIVITY RELATION;
STEREOISOMERISM;
SYNTHESIS;
LEISHMANIA DONOVANI;
ANIMALS;
ANTIPROTOZOAL AGENTS;
CELL LINE;
COMPUTER SIMULATION;
ELECTROCHEMISTRY;
INHIBITORY CONCENTRATION 50;
LEISHMANIA DONOVANI;
MACROPHAGES;
MICE;
MODELS, MOLECULAR;
MOLECULAR CONFORMATION;
MOLECULAR STRUCTURE;
NEURONS;
QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;
QUANTUM THEORY;
QUINAZOLINES;
SOFTWARE;
STEREOISOMERISM;
|
|
EID: 0036009898
PISSN: 09680896
EISSN: None
Source Type: Journal
DOI: 10.1016/S0968-0896(02)00013-5 Document Type: Article |
|
Times cited : (124)
|
|
References (34)
|
