Adrenal progestogen and androgen production in 21-hydroxylase-deficient nonclassic adrenal hyperplasia is partially independent of adrenocorticotropic hormone stimulation

Fertility and Sterility

Volumn 77, Issue 4, 2002, Pages 750-753

  Sánchez, Luis A ^a   Morán, Carlos ^a,b,c   Reyna, Rosario ^a   Ochoa, Tatiana ^a   Boots, Larry R ^a   Azziz, Ricardo ^a,d  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b INSTITUTO MEXICANO DEL SEGURO SOCIAL   (Mexico)

^c University of Alabama at Birmingham   (United States)

^d NONE   (United States)

Author keywords

17 hydroxyprogesterone; Adrenal androgens; Glucocorticoid suppression; Hyperandrogenism; Nonclassic adrenal hyperplasia; Progestogens

Indexed keywords

ANDROGEN; ANDROSTENEDIONE; CORTICOTROPIN; DEXAMETHASONE; GESTAGEN; GROWTH HORMONE RELEASING FACTOR; HYDROCORTISONE; HYDROXYPROGESTERONE; LEUPRORELIN; PRASTERONE SULFATE; DIAGNOSTIC AGENT; GLUCOCORTICOID; PRASTERONE; PROGESTERONE; STEROID 21 MONOOXYGENASE;

ADRENAL SUPPRESSION; ANDROGEN SYNTHESIS; BODY MASS; CLINICAL ARTICLE; CONFERENCE PAPER; CONGENITAL ADRENAL HYPERPLASIA; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; ENZYME KINETICS; FEMALE; HORMONAL REGULATION; HUMAN; PRIORITY JOURNAL; STEROIDOGENESIS; TREATMENT OUTCOME; ADRENAL GLAND; ADULT; ARTICLE; BIOSYNTHESIS; BLOOD; DRUG EFFECT; KINETICS; METABOLISM; MIDDLE AGED; PROSPECTIVE STUDY;

17-ALPHA-HYDROXYPROGESTERONE; ADRENAL GLANDS; ADRENAL HYPERPLASIA, CONGENITAL; ADRENOCORTICOTROPIC HORMONE; ADULT; ANDROGENS; ANDROSTENEDIONE; DEHYDROEPIANDROSTERONE; DEXAMETHASONE; FEMALE; GLUCOCORTICOIDS; HUMANS; HYDROCORTISONE; KINETICS; LEUPROLIDE; MIDDLE AGED; PROGESTERONE; PROGESTINS; PROSPECTIVE STUDIES; STEROID 21-HYDROXYLASE;

EID: 0036009807     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0015-0282(01)03236-8     Document Type: Conference Paper

References (10)

1. Non-classic adrenal hyperplasia: Current concepts
2. The hypothalamic-pituitary-adrenal axis in partial (late-onset) 21-hydroxylase deficiency
3. The 21-hydroxylase-deficient adrenal hyperplasias: More than ACTH oversecretion
4. A multicenter study of women with nonclassical congenital adrenal hyperplasia: Relationship between genotype and phenotype
5. Ovarian suppression reduces clinical and endocrine expression of late-onset congenital adrenal hyperplasia due to 21-hydroxylase deficiency
6. Adrenal androgen excess in the polycystic ovary syndrome: Sensitivity and responsivity of the hypothalamic-pituitary-adrenal axis
7. Effects of continued adrenal corticotropin stimulation on the mineralocorticoid hormones in classical and nonclassical simple virilizing types of 21-hydroxylase deficiency
8. Pituitary-adrenal responses to corticotropin-releasing factor in late onset 21-hydroxylase deficiency
9. Adrenal incidentaloma and patients with homozygous or heterozygous congenital adrenal hyperplasia
10. Adrenocortical hyperresponsivity to adrenocorticotropic hormone: A mechanism favoring the normal production of cortisol in 21-hydroxylase-deficient nonclassic adrenal hyperplasia