No change in dopamine D1 receptor in vivo binding in rats after sub-chronic haloperidol treatment

Canadian Journal of Physiology and Pharmacology

Volumn 80, Issue 1, 2002, Pages 36-41

  Sanci, Vito ^a   Houle, Sylvain ^a   DaSilva, Jean N ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

Behavioral D1 supersensitivity; Positron emission tomography; Tardive dyskinesia; Typical neuroleptics; Vacuous chewing movements

Indexed keywords

8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; CARBON 11; DOPAMINE 1 RECEPTOR; DOPAMINE 1 RECEPTOR STIMULATING AGENT; HALOPERIDOL; SKF 82957; UNCLASSIFIED DRUG; BENZAZEPINE DERIVATIVE; DOPAMINE RECEPTOR BLOCKING AGENT; DOPAMINE RECEPTOR STIMULATING AGENT;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CONTROLLED STUDY; DRUG EFFECT; DRUG RECEPTOR BINDING; GROOMING; IN VIVO STUDY; INVOLUNTARY MOVEMENT; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REARING; SCHIZOPHRENIA; SUPERSENSITIVITY; TARDIVE DYSKINESIA; ANIMAL; METABOLISM; RADIOASSAY; SPRAGUE DAWLEY RAT; STEREOTYPY;

(R)-2,3,4,5-TETRAHYDRO-8-CHLORO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL; ANIMALS; BEHAVIOR, ANIMAL; BENZAZEPINES; DOPAMINE AGONISTS; DOPAMINE ANTAGONISTS; GROOMING; HALOPERIDOL; MALE; RADIOLIGAND ASSAY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE D1; STEREOTYPED BEHAVIOR;

EID: 0036008782     PISSN: 00084212     EISSN: None     Source Type: Journal    
DOI: 10.1139/y02-002     Document Type: Article

References (42)

1. Effects of antipsychotic drugs on dopamine and serotonin contents and metabolites, dopamine and serotonin transporters, and serotonin1A receptors
2. The problem of antipsychotic treatment for functional imaging in Huntington's disease: Receptor binding, gene expression and locomotor activity after sub-chronic administration and wash-out of haloperidol in the rat
3. Involvement of adenosine and glutamate receptors in the induction of c-fos in the striatum by haloperidol
4. Tardive dyskinesia and atypical antipsychotic drugs
5. 2 receptors in the nucleus accumbens in jaw movements of rats: A critical role of the shell
6. 11C]SCH 23390 in rat brain
7. 11C]SKF 82957: Synthesis and in vivo characterization in rats
8. 1-like" dopamine receptor agonists
9. Haloperidol-induced vacuous chewing in rats: Suppression by alpha- methyltyrosine
10. Effects of acute or chronic administration of risperidone on motor and sexual behavior of male rats
11. Effects of rating parameters on assessment of neuroleptic-induced vacuous chewing movements
12. In vivo evaluation of R/S-[C-11]SKF 82957 in rats as a D-1 agonist tracer for PET: Effect of endogenous dopamine and chronic D-1 and D-2 antagonists
13. The neuropathology of schizophrenia. A critical review of the data and their interpretation
14. 2 receptors: Homogenate binding and autoradiographic studies
15. Differential effects of repeated treament with haloperidol and clozapine on dopamine release and metabolism in the striatum and the nucleus accumbens
16. 1 receptors and their desensitization after chronic treatment
17. Are animal studies of antipsychotics appropriately dosed? Lessons from the bedside to the bench
18. 1 rat somatomammotrophic cells
19. Increased dopamine transmission in schizophrenia: Relationship to illness phases
20. Dopamine receptor agonist- and antagonist-induced behaviors in primates previously treated with dopamine receptor antagonists: The pathogenetic mechanisms of acute oral dyskinesia
21. 1 receptor: Focus on negative symptoms
22. 1 receptors in schizophrenia
23. 2 receptor stimulation attenuates haloperidol-induced behavioral supersensitivity and receptor up-regulation
24. Striatal c-fos levels do not correlate with haloperidol-induced behavioral supersensitivity
25. (±)-3-Allyl-6-bromo-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3- benzazepin, a new high-affinity D1 do-pamine receptor ligand: Synthesis and structure-activity relationship
26. Central D2-dopamine receptor occupancy in relation to antipsychotic drug effects: A double-blind PET study of schizophrenic patients
27. 2 receptor occupancy in relation to clozapine serum concentration: A PET study of schizophrenic patients
28. Chronic treatment with clozapine or haloperidol differentially regulates dopamine and serotonin receptors in rat brain
29. 2 receptor blocking activity
30. 2 receptor agonists and antagonists in monkeys withdrawn from long-term neuroleptic treatment
31. No changes in dopamine D(1) receptor mRNA expressing neurons in the dorsal striatum of rats with oral movements induced by long-term haloperidol administration
32. Dopaminergic activity of substituted 6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
33. Combined antagonism of adrenoceptors and dopamine and 5-HT receptors underlies the atypical profile of clozapine
34. 11C]SCH 23390)
35. Possible genetic factors underlying the pathophysiology of tardive dyskinesia
36. 3H]SCH 23390 binding to dopamine D1, receptors after long-term haloperidol treatment: Lack of correspondence with the development of vacuous chewing movements
37. Chronic haloperidol-induced changes in regional dopamine release and metabolism and neurotensin content in rats
38. 1 receptor pharmacology
39. Antipsychotic drug doses and neuroleptic/dopamine receptors
40. 1 binding site correlates of haloperidol-induced oral dyskinesias in rat
41. 11C]SKF 82957 in vivo in rat brain
42. 1A receptor function in a rodent model of tardive dyskinesia