The use of lipid emulsions for the iv administration of a new water soluble polyene antibiotic, SPK-843

Journal of Antimicrobial Chemotherapy

Volumn 49, Issue 2, 2002, Pages 321-325

  Mozzi, G ^a   Benelli, P ^a   Bruzzese, T ^a   Galmozzi, M R ^a   Bonabello, A ^a  

^a Societa Prodotti Antibiotici SpA ^*  (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ASCORBIC ACID; DRUG VEHICLE; GLUCOSE; INTRALIPID; LACTOSE; LIPID EMULSION; N DIMETHYLAMINOACETYLPARTRICIN A 2 DIMETHYLAMINOETHYLAMIDE DIASCORBIC ACID; POLYENE ANTIBIOTIC AGENT; SPK 843; UNCLASSIFIED DRUG; WATER; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; POLYENE; SPA S 843;

ACIDITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG INFUSION; DRUG SOLUBILITY; DRUG STABILITY; DRUG STRUCTURE; DRUG TOLERANCE; MALE; NONHUMAN; PHLEBITIS; RABBIT; VEIN INJURY; VEIN OCCLUSION; ANIMAL; CHEMISTRY; DRUG EFFECT; DRUG SCREENING; EXTERNAL EAR; INTRAVENOUS DRUG ADMINISTRATION; METHODOLOGY; PHYSIOLOGY; SOLUBILITY; STATISTICS; VASCULARIZATION; VEIN;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTIFUNGAL AGENTS; DRUG EVALUATION, PRECLINICAL; EAR, EXTERNAL; FAT EMULSIONS, INTRAVENOUS; INFUSIONS, INTRAVENOUS; MALE; POLYENES; RABBITS; SOLUBILITY; VEINS;

EID: 0036008192     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/49.2.321     Document Type: Article

References (9)

1. Amphotericin B: New life for an old drug
2. Amphotericin B lipid complex: Recent progress
3. Amide derivatives of partricin A with potent antifungal activity
4. Anticandidal activity of SPA-S-843, a new polyenic drug
5. Comparative pharmacokinetics of three preparations of the new antifungal SPK-843
6. Stability of amphotericin B in an extemporaneously prepared i.v. fat emulsion
7. The use of commercially available lipid emulsions for the preparation of amphotericin B lipid admixtures
8. Amphotericin B in lipid emulsions: Stability, compatibility and in vitro antifungal activity
9. Photo-stability of a solution of a new polyene antibiotic derived from partricin