In vivo advantage of combined administration with CPT-11 and 5-fluorouracil in rats

Journal of Experimental Therapeutics and Oncology

Volumn 2, Issue 1, 2002, Pages 42-46

  Satoh, Hiroaki ^a   Ohtomo, Masao ^b   Ishikawa, Hiroichi ^a   Kamma, Hiroshi ^c   Yamashita, Yuko T ^d   Ohtsuka, Morio ^a   Sekizawa, Kiyohisa ^a  

^a University of Tsukuba   (Japan)

^b Tsukuba Animal Research Laboratory   (Japan)

^c UNIVERSITY OF TSUKUBA   (Japan)

^d UNIVERSITY HOSPITAL OF THE RYUKYUS   (Japan)

Author keywords

5 fluorouracil; Chemotherapy; Combination; CPT 11

Indexed keywords

ANTINEOPLASTIC AGENT; CAMPTOTHECIN; DRUG DERIVATIVE; FLUOROURACIL; IRINOTECAN;

ANIMAL; ARTICLE; CELL CULTURE; EXPERIMENTAL NEOPLASM; LUNG TUMOR; MALE; RAT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; BODY WEIGHT; CANCER COMBINATION CHEMOTHERAPY; CANCER GROWTH; CELL GROWTH; CONTROLLED STUDY; DISEASE ASSOCIATION; DOSE RESPONSE; LUNG CARCINOMA; MORTALITY; NONHUMAN; PRIORITY JOURNAL; TUMOR CELL; WEIGHT REDUCTION;

ANIMALS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CAMPTOTHECIN; FLUOROURACIL; LUNG NEOPLASMS; MALE; NEOPLASMS, EXPERIMENTAL; RATS; TUMOR CELLS, CULTURED; ANIMAL; SUPPORT, NON-U.S. GOV'T;

EID: 0036007544     PISSN: 13594117     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1359-4117.2002.01005.x     Document Type: Article

References (16)

1. Future directions in the treatment of non-small cell lung cancer
2. Antitumor activity of 7-ethyl-10-[4-(1-piperidino)-1-piperidono]carbonyloxy-camptothecin, a new water-soluble derivative of camptothecin, against murine tumors
3. Antitumor activity of a new comptothecin derivative, SN-22, against various murine tumors
4. Metabolism and pharmacokinetics of the camptothecin analogue CPT-11 in the mouse
5. A phase II study of 72-hour continuous infusion consisting of cisplatin and 5-fluorouracil for treatment of non-small cell lung cancer
6. Combination therapy of CPT-11, a camptothecin derivative, with various antitumor drugs against L1210 leukemia
7. Effects of CPT-11 in combination with other anticancer agents in culture
8. Advantage of combined treatment of CPT-11 and 5-fluorouracil
9. Sequence-dependent modulation of anticancer drug activity by 7-ethyl-10-hydroxycamptothecin in an HST-1 human squamous carcinoma cell line
10. Experimental and clinical study of interactions between fluorinated pyrimidine derivatives and anticoagulants
11. Exploitable mechanisms in combined radiotherapy-chemotherapy: The concept of additivity
12. Effects of harringtonine in combination with activicin, Adriamycin, L-asparaginase, cytosine arabinoside, dexamethasone, fluorouracil, or methotrexate on human acute myelogenous leukemia cell line LG-1
13. CPT-11. The European experience
14. Irinotecan plus cisplatin in patients with advanced non-small-cell lung cancer
15. Simultaneous administration of CPT-11 and fluorouracil: Alteration of the pharmacokinetics of CPT-11 and SN-38 in patients with advanced colorectal cancer
16. CPT-11 converting enzyme from rat serum: Purification and some properties