The measles virus hemagglutinin downregulates the cellular receptor SLAM (CD150)

Archives of Virology

Volumn 147, Issue 1, 2002, Pages 195-203

  Tanaka, K ^a   Minagawa, H ^a   Xie, M F ^a   Yanagi, Y ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

MEASLES VIRUS;

CD150 ANTIGEN; CELL SURFACE RECEPTOR; GLYCOPROTEIN; IMMUNOGLOBULIN; LEUKOCYTE ANTIGEN; VIRUS HEMAGGLUTININ; VIRUS RECEPTOR;

ANIMAL; ARTICLE; B LYMPHOCYTE; CELL CULTURE; CELL LINE; CHO CELL; DOWN REGULATION; GENETIC TRANSFECTION; HAMSTER; HUMAN; MEASLES; MEASLES VIRUS; METABOLISM; MONONUCLEAR CELL; VIROLOGY;

ANIMALS; ANTIGENS, CD; B-LYMPHOCYTES; CELL LINE, TRANSFORMED; CHO CELLS; CRICETINAE; DOWN-REGULATION; GLYCOPROTEINS; HEMAGGLUTININS, VIRAL; HUMANS; IMMUNOGLOBULINS; LEUKOCYTES, MONONUCLEAR; MEASLES; MEASLES VIRUS; RECEPTORS, CELL SURFACE; RECEPTORS, VIRUS; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0036007494     PISSN: 03048608     EISSN: None     Source Type: Journal    
DOI: 10.1007/s705-002-8312-0     Document Type: Article

References (29)

1. Engagement of the signaling lymphocytic activation molecule (SLAM) on activated T cells results in IL-2-independent, cyclosporin A-sensitive T cell proliferation and IFN-γ production
2. Differential receptor usage by measles virus strains
3. A novel receptor involved in T-cell activation
4. The human CD46 molecule is a receptor for measles virus (Edmonston strain)
5. CD150 (SLAM) is a receptor for measles virus but is not involved in viral contact-mediated proliferation inhibition
6. Morbillivirus downregulation of CD46
7. Measles virus
8. A single amino acid change in the hemagglutinin protein of measles virus determines its ability to bind CD46 and reveals another receptor on marmoset B cells
9. T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV
10. Marmoset lymphoblastoid cells as a sensitive host for isolation of measles virus
11. Cell-to-cell contact via measles virus haemagglutinin-CD46 interaction triggers CD46 downregulation
12. Identification of two amino acids in the hemagglutinin glycoprotein of measles virus (MV) that govern hemadsorption, HeLa cell fusion, and CD46 downregulation: Phenotypic markers that differentiate vaccine and wild-type MV strains
13. Monospecific antibody to the haemagglutinin of measles virus
14. Human membrane cofactor protein (CD46) acts as a cellular receptor for measles virus
15. Measles virus haemagglutinin induces down-regulation of gp57/67, a molecule involved in virus binding
16. Measles virus-induced immune suppression in the cotton rat (sigmodon hispidus) model depends on viral glycoproteins
17. Measles viruses on throat swabs from measles patients use signaling lymphocytic activation molecule (CDw150) but not CD46 as a cellular receptor
18. V domain of human SLAM (CDw150) is essential for its function as a measles virus receptor
19. Immunodeficiency virus cDNA synthesis in resting T lymphocytes is regulated by T cell activation signals and dendritic cells
20. CD46 is a cellular receptor for human herpesvirus 6
21. Interaction of measles virus glycoproteins with the surface of uninfected peripheral blood lymphocytes induces immunosuppression in vitro
22. Differential downregulation of CD46 by measles virus strains
23. Receptor usage and differential downregulation of CD46 by measles virus wild-type and vaccine strains
24. Quantitative analysis of membrane cofactor protein (MCP) of complement: High expression of MCP on human leukemia cell lines, which is down-regulated during cell differentiation
25. Characterization of a cell surface glycoprotein IPO-3, expressed on activated human B and T lymphocytes
26. The hemagglutinin of recent measles virus isolates induces cell fusion in a marmoset cell line, but not in other CD46-positive human and monkey cell lines, when expressed together with the F protein
27. Virus entry is a major determinant of cell tropism of Edmonston and wild-type strains of measles virus as revealed by vesicular stomatitis virus pseudotypes bearing their envelope proteins
28. SLAM (CDw150) is a cellular receptor for measles virus
29. Measles virus inhibits mitogen induced T cell proliferation but does not directly perturb the T cell activation process inside the cell