Regulation of myocardial gene expression during heart development

Revista Espanola de Cardiologia

Volumn 55, Issue 2, 2002, Pages 167-184

  Franco, Diego ^a   Domínguez, Jorge ^a   del Pilar de Castro, María ^a   Aránega, Amelia ^a  

^a UNIVERSITY OF JAÉN   (Spain)

Author keywords

Cardiogenesis; Gene expression; Transcriptional regulation

Indexed keywords

CONTRACTILE PROTEIN; ION CHANNEL; MUSCLE PROTEIN; TRANSCRIPTION FACTOR;

ARTICLE; CONTROLLED STUDY; DEVELOPMENTAL BIOLOGY; EMBRYO DEVELOPMENT; EMBRYOLOGY; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE THERAPY; GENETIC HETEROGENEITY; HEART DEVELOPMENT; HEART MUSCLE; HUMAN; MOLECULAR BIOLOGY; MULTIGENE FAMILY; TISSUE SPECIFICITY; TRANSGENE; ANIMAL; FORECASTING; GENE; HEART; MOUSE; PHYSIOLOGY; PRENATAL DEVELOPMENT; RAT; REVIEW;

ANIMALS; FORECASTING; GENE EXPRESSION REGULATION; GENES; HEART; HUMANS; MICE; RATS; TRANSCRIPTION FACTORS;

EID: 0036006007     PISSN: 03008932     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0300-8932(02)76576-7     Document Type: Article

References (113)

1. Controlling TGF-β signalling
2. A role of bone morphogenetic proteins in the induction of cardiac myogenesis
3. BMP signalling is required for heart formation in vertebrates
4. Embryonic development of the heart: I. Electron microscopic study of myocardial development in the early chicken embryo
5. Symmetry and Laterality in the human heart: Developmental implications
6. Molecular anatomy of the developing heart
7. Patterns of gene expression in the developing myocardium: Towards a morphologically integrated transcriptional model
8. Cardiac Development: A morphologically integrated molecular approach
9. Myocardialization of the cardiac outflow tract
10. The structure of the mouse heart in late fetal stages
11. Cardiac pathology
12. Primitive-streak origin of the cardiovascular system in avian embryos
13. Patterns of expression of sarcoplasmic reticulum Ca2+ATPase and phospholamban mARNs during rat heart development
14. Presence of functional sarcoplasmic reticulum in the developing heart and its confinement to chamber myocardium
15. Fashioning the vertebrate heart: Earliest embryonic decisions
16. Nkx2.5: A novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants
17. Subdivision of the cardiac Nkx2.5 expression doamin into myogenic and nonmyogenic compartments
18. Pitx2 participates in the late phase of the pathway controlling left-right asymmetry
19. The homeobox gene Pitx2: Mediator of asymmetric left-right signalling in vertebrate heart and gut loping
20. Pitx-2 expression defines a left cardiac lineage and provides evidence for the existence of ventricular isomerism in iv mice
21. Cardiac expression of the ventricle-specific homeobox gene Irx4 is modulated by Nkx2.5 and dHAND
22. Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis
23. GATA4 transcription factor is required for ventral morphogenesis and heart tube formation
24. The transcription factor GATA6 is essential for early extraembryonic development
25. Localization of transcription factor GATA-4 to regions of the mouse embryo involved in cardiac development
26. GATA-6: A zinc finger transcription factor that is expressed in multiple cell lineages derived from lateral mesoderm
27. GATA-5: A transcriptional activator expressed in a novel temporally and spatially-restricted pattern during embryonic development
28. The cardiac transcription factors Nkx2.5 and GATA-4 are mutual cofactors
29. Mef2 gene expression marks the cardiac and skeletal muscle lineages during mouse embryogenesis
30. Control of mouse cardiac morphogenesis and myogenesis by transcription factor MEF2C
31. Skeletal muscle formation in vertebrates
32. Homeobox genes and heart development
33. Expression of the novel basic Helix-loop-Helix gene eHAND in neural crest derivates and extraembryonic membranes during mouse development
34. A subclass of bHLH Proteins Required for Cardiac Morphogenesis
35. Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND
36. The Hand1 bHLH transcription factor is essential for placentation and cardiac morphogenesis
37. HRT1, HRT2 and HTR3: A new subclass of bHLH transcription factors marking specific cardiac, somitic and pharyngeal arch segments
38. Somitogenesis: Segmenting a vertebrate
39. Avian serum response factor expression restricted primarily to muscle cell lineages is required for α-actin gene transcription
40. MesP1: A novel basic helix-loop-helix protein expressed in the nascent mesodermal cells during mouse grastrulation
41. MesP1 is expressed in the heart prescursor cells and required for the formation of a single heart tube
42. CARP, a cardiac ankyrin repeat protein, is downstream in the Nkx2.5 homoebox gene pathway
43. Identification of a novel cardiac lineage-associated protein(cCLP-1): A candidate regulator of cardiogenesis
44. Identification of a novel cardiac-specifi transcript critical for cardiac myocyte differentiation
45. A novel myocyte-specific gene Midori promotes differentiation of P19CL6 cells intro cardiomyocytes
46. Cooperative interaction between GATA-4 and GATA-6 regulates myocardial gene expression
47. Tbx5 associates with Nkx2.5 and synergistically promotes cardiomyocyte differentiation
48. Chamber formation and morphogenesis in the developing mammalian heart
49. Regionalization of transcriptional potential in the myocardium
50. A retinoic acid-inducible transgenic marker of the sino-atrial development in the mouse heart
51. The chicken GATA-6 locus contains multiple control regions that confer distinct patterns of heart region-specific expression in transgenic mouse embryos
52. Compartment-specific myosin light chain 3F transgene expression in the embryonic mouse heart
53. The primitive cardiac regions in the straight tube heart (stage 9) and their anatomical expression in the mature heart: An experimental study in the chick embryo
54. Living morphogenesis of the heart
55. MLC3F transgene expression in iv mutant mice reveals the importance of left-right signalling pathway for the acquisition of atrial but not ventricular compartment identity
56. Development of the cardiac heartbeat in early chick embryos is regulated by regional cues
57. Cell interactions in cardiac development
58. Molecular diversity of myofibrillar proteins: Gene regulation and functional significance
59. Diversification of cardiomyocytes cell lineages during early heart development
60. Expression of the atrial-specific myosin heavy chain AMHC1 and the establishment of anteroposterior polarity in the developing chicken heart
61. Regulation of chamber-specific gene expression in the developing heart by Irx4
62. Homeodomain factor Nkx2-5 controls left/right asymmetric expression of bHLH gene eHand during murine heart development
63. EFIA/YB-1 is a component of cardiac HF1A binding activity and positively regulates transcription of the myosin light-chain 2v gene
64. Desmin sequence elements regulating skeletal muscle-specific expression in transgenic mice
65. Expression of the SM22alpha promotor in transgenic mice provides evidence for distinct transcriptional regulatory programs in vascular and visceral smooth muscle cells
66. Myosin light chain 3F regulatory sequences confer regionalized cardiac and skeletal muscle expression in transgenic mice
67. An HF1a/HF-1b/MEF-2 combinatorial element confers cardiac ventricular specificity and establishes an anterior-posterior gradient of expression
68. Mechanisms of left-right asymmetry: What's right and what's left?
69. The transcriptional building blocks of the heart
70. Myosin light chain 2a and 2v identifies the embryonic outflow tract myocardium in the developing rodent heart
71. Dynamic left/right regionalization of endogenous myosin light chain 3F transcripts in the developing mouse heart
72. Cardiosensor mice and transcriptional subdomains of the vertebrate heart
73. Developmental expression of rat cardiac troponin I mARN
74. Connexions in mammalian heart function
75. Spatial distribution of connexin-43, the major cardiac gap junction protein, in the developing and adult rat heart
76. Developmental changes of connexin40 and connexin43 mARN-distribution patterns in the rat heart
77. Developmental regulation of connexin40 gene expression in mouse heart correlates with the differentiation of the conduction system
78. Connexin45 expression is preferentially associated with the ventricular conduction system in mouse and rat heart
79. Connexin45 (α6) expression delineates and extended conduction system in the embryonic and mature rodent heart
80. Downregulation of connexin 45 gene products during mouse heart development
81. Regional differences in the electrophysiology of ventricular cells: Physiological and clinical implications
82. Cardiac sodium channel and inherited arrythmia syndromes
83. Positional cloning of a novel potassium channel gene: KvQTL1 mutations cause cardiac arrhythmias
84. KvLQT1 and IsK (minK) proteins associate to form I(Ks) cardiac potassium current
85. A minK-HERG complex regulates the cardiac potassium current IKr
86. MiRP forms IKr potassium channels with HERG and is associated with cardiac arrythmia
87. A constitutively open potassium channel formed by KCNQ1 and KCNE3
88. KCNE2 confers background current characteristics to cardiac KCNQ1 potassium channel
89. Divergent expression of delayed rectifier K+ channel subunits during mouse heart development
90. Patterning the embryonic heart: Identification of five Iroquois homeobox genes in the developing heart
91. Chamber-specific cardiac expression of Tbx5 and heart defects in Holt-Oram syndrome
92. Suppression of atrial myosin gene expression occurs independently in the left and right ventricles of the developing mouse heart
93. Multiple transcriptional domains, with distinct left and right components, in the atrial chambers of the developing heart
94. An atrioventricular canal domain defined by cardiac troponin I transgene expression in the embryonic myocardium
95. Tissue-specific regulation of the α-myosin heavy chain gene promoter in transgenic mice
96. Developmental modulation of a β-myosin heavy chain promoter-driven transgene
97. Molecular Pathways Controlling Heart Development
98. Visualization and functional characterization of the developing musrine cardiac conduction system
99. The arterial pole of the mouse heart forms from FGF10-expressing cells in pharyngeal mesoderm
100. Cardiac musculature of the cranial vena cava in the rat
101. Development of the myocardium of the atrioventricular canal and the vestibular spine in the human heart
102. The conotruncus and its septation at the advent of the molecular biology era
103. Development of the conduction system of the vertebrate heart
104. Molecular characterization of the ventricular conduction system in the developing mouse heart: Topographical correlation in normal and congenitally malformed hearts
105. Development of the conduction system
106. Spatial distribution of "tissue specific" antigens in the developing human heart and skeletal muscle: II. An immunohistochemical analysis of myosin heavy chain isoform expression patterns in the embryonic heart
107. Congenital heart disease caused by mutations in the transcription factor Nkx2.5
108. Mutations in the cardiac transcription factor Nkx2.5 affect diverse cardiac developmental pathways
109. Cardiac septal and valvular dysmmorphogenesis in mice heterozygous for mutations in the homeobox gene Nkx2.5
110. Elevated expression of Nkx2.5 in developing myocardial conduction cells
111. In situ analysis of the cardiac muscle gene program during embryogenesis
112. Expression of the cardiac ventricular alpha and beta myosin heavy chain genes is developmentally and hormonally regulated