Characterizing the fragmentation of 2,5-bis (4-amidinophenyl)furan-bis-O-methylamidoxime and selected metabolites using ion trap mass spectrometry

Rapid Communications in Mass Spectrometry

Volumn 16, Issue 11, 2002, Pages 1078-1085

  Zhou, Lian ^a   Voyksner, Robert D ^d   Thakker, Dhiren R ^a   Stephens, Chad E ^b   Anbazhagan, Mariappan ^b   Boykin, David W ^b   Hall, James E ^a,c   Tidwell, Richard R ^a,c  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b GEORGIA STATE UNIVERSITY   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d LCMS Limited   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMICROBIAL AGENTS; AROMATIC COMPOUNDS; ATOMS; BIOMOLECULES; DEUTERIUM; ELECTROSPRAY IONIZATION; IONS; MASS SPECTROMETRY; ORGANIC POLLUTANTS;

BOND CLEAVAGES; CLINICAL EVALUATION; DRUG CANDIDATES; ELECTRON IONS; FRAGMENTATION PATHWAYS; HOMOLYTIC BONDS; ION-TRAP MASS SPECTROMETRY; PHASE II; PRODRUGS; PRODUCT IONS;

METABOLITES;

2,5 BIS(4 AMIDINOPHENYL)FURAN; 2,5 BIS(4 AMIDINOPHENYL)FURAN BIS O METHYLAMIDOXINE; 2,5-BIS(4-AMIDINOPHENYL)FURAN; ANTIINFECTIVE AGENT; ANTITRYPANOSOMAL AGENT; BENZAMIDINE DERIVATIVE; DB 289; DB 75; DEUTERIUM OXIDE; DRUG METABOLITE; FURAN DERIVATIVE; PRODRUG; UNCLASSIFIED DRUG;

AFRICAN TRYPANOSOMIASIS; ANALYTIC METHOD; ARTICLE; CHEMICAL BOND; CHEMICAL STRUCTURE; DRUG DETERMINATION; MASS SPECTROMETRY; METABOLIC ACTIVATION; METHODOLOGY; PNEUMOCYSTIS CARINII PNEUMONIA; ELECTROSPRAY MASS SPECTROMETRY;

BENZAMIDINES; MOLECULAR STRUCTURE; PRODRUGS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TRYPANOCIDAL AGENTS;

EID: 0036001221     PISSN: 09514198     EISSN: None     Source Type: Journal    
DOI: 10.1002/rcm.676     Document Type: Article

References (7)