Use of lidocaine-prilocaine patch to decrease intramuscular injection pain does not adversely affect the antibody response to diphtheria-tetanus-acellular pertussis-inactivated poliovirus-Haemophilus influenzae type b conjugate and hepatitis B vaccines in infants from birth to six months of age

Pediatric Infectious Disease Journal

Volumn 21, Issue 5, 2002, Pages 399-405

  Halperin, Beth A ^a   Halperin, Scott A ^a   McGrath, Patrick ^a   Smith, Bruce ^a   Houston, Tricia ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

Author keywords

Diphtheria tetanus acellular pertussis inactivated poliovirus Haemophilus influenzae type b; Hepatitis B vaccine; Immunogenicity; Lidocaine prilocaine (EMLA); Pain

Indexed keywords

DIPHTHERIA PERTUSSIS POLIOMYELITIS TETANUS HAEMOPHILUS INFLUENZAE TYPE B VACCINE; DIPHTHERIA PERTUSSIS POLIOMYELITIS TETANUS VACCINE; DIPHTHERIA PERTUSSIS TETANUS HAEMOPHILUS INFLUENZAE TYPE B VACCINE; EMLA; HEPATITIS B VACCINE; PENTACEL; UNCLASSIFIED DRUG; DIPHTHERIA PERTUSSIS TETANUS VACCINE; HAEMOPHILUS VACCINE; LIDOCAINE; LOCAL ANESTHETIC AGENT; POLIOMYELITIS VACCINE; PRILOCAINE;

ANALGESIA; ANTIBODY RESPONSE; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG RESPONSE; DRUG SAFETY; EDEMA; ERYTHEMA; FEMALE; HUMAN; IMMUNITY; INFANT; INJECTION PAIN; LOCAL ANESTHESIA; MALE; NEWBORN; NORMAL HUMAN; PAIN ASSESSMENT; PALLOR; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SEROCONVERSION; VACCINATION; ANTIBODY PRODUCTION; DOUBLE BLIND PROCEDURE; IMMUNOLOGY; MULTICENTER STUDY; OINTMENT; PAIN; TOPICAL DRUG ADMINISTRATION;

ADMINISTRATION, TOPICAL; ANESTHETICS, LOCAL; ANTIBODY FORMATION; DIPHTHERIA-TETANUS-ACELLULAR PERTUSSIS VACCINES; DOUBLE-BLIND METHOD; FEMALE; HAEMOPHILUS VACCINES; HEPATITIS B VACCINES; HUMAN; INFANT; INFANT, NEWBORN; LIDOCAINE; MALE; OINTMENTS; PAIN; POLIOVIRUS VACCINE, INACTIVATED; PRILOCAINE; SUPPORT, NON-U.S. GOV'T; HUMANS;

EID: 0035999345     PISSN: 08913668     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006454-200205000-00010     Document Type: Article

References (17)

1. Pain perception and effectiveness of the eutectic mixture of local anesthetics in children undergoing venipuncture
2. Pain-free injection in infants. Use of a lignocaine-prilocaine cream to prevent pain at intravenous induction of general anaesthesia in 1-5-year-old children
3. Reduction of pain at venous cannulation in children with a eutectic mixture of lidocaine and prilocaine (EMLA cream): Comparison with placebo cream and no local premedication
4. Topical skin anesthesia for venous, subcutaneous drug reservoir and lumbar punctures in children
5. Curettage of molluscum contagiosum in children: Analgesia by topical application of a lidocaine/prilocaine cream (EMLA)
6. Efficacy and safety of lidocaine-prilocaine cream for pain during circumcision
7. Analgesia for neonatal circumcision: A randomized controlled trial of EMLA cream vs. dorsal penile nerve block
8. Age-related response to lidocaine-prilocaine (EMLA) emulsion and effect of music distraction on the pain of intravenous cannulation
9. A eutectic mixture of lidocaine and prilocaine for alleviating vaccination pain in infants
10. Use of lidocaineprilocaine cream for vaccination pain in infants
11. Lidocaine-prilocaine patch decreases the pain associated with the subcutaneous administration of measles-mumps-rubella vaccine but does not adversely affect the antibody response
12. Effect of lidocaine-prilocaine cream on pain from subcutaneous injection
13. A revised measure of acute pain in infants
14. Approximate interval estimation of a ratio of binomial parameters: A review and correction for skewness
15. No negative influence of EMLA application before BCG vaccination
16. Vapocoolant spray is equally effective as EMLA cream in reducing immunization pain in school-aged children
17. EMLA cream as a local anaesthetic in MMR vaccination