Transdermal delivery of pergolide from surfactant-based elastic and rigid vesicles: Characterization and in Vitro transport studies

Pharmaceutical Research

Volumn 19, Issue 7, 2002, Pages 991-997

  Honeywell Nguyen, P L ^a   Frederik, P M ^b   Bomans, P H H ^b   Junginger, H E ^a   Bouwstra, J A ^a,c  

^a LEIDEN UNIVERSITY   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

^c LEIDEN UNIVERSITY   (Netherlands)

Author keywords

Elastic vesicles; Pergolide; Transdermal delivery

Indexed keywords

ESTER DERIVATIVE; OCTAOXYETHYLENE LAURATE ESTER; PERGOLIDE; SUCROSE LAURATE; SURFACTANT; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; DRUG FORMULATION; DRUG PENETRATION; DRUG SOLUBILITY; DRUG TRANSPORT; ELASTICITY; HUMAN; HUMAN TISSUE; IN VITRO STUDY; MICELLE; MOLECULAR SIZE; MOLECULAR STABILITY; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RIGIDITY; SURFACE PROPERTY; TRANSPORT VESICLE; CHEMISTRY; COMPARATIVE STUDY; DRUG EFFECT; INTRADERMAL DRUG ADMINISTRATION; METABOLISM; METHODOLOGY; PHYSIOLOGY; SKIN; TRANSPORT AT THE CELLULAR LEVEL;

ADMINISTRATION, CUTANEOUS; BIOLOGICAL TRANSPORT; COMPARATIVE STUDY; DRUG DELIVERY SYSTEMS; ELASTICITY; HUMAN; IN VITRO; MICELLES; PERGOLIDE; SKIN; SURFACE-ACTIVE AGENTS; HUMANS;

EID: 0035997332     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1016466406176     Document Type: Article

References (21)

1. Triamcinolone permeation from different liposome formulations through rat skin in vitro
2. Corticosteroid dermal delivery with skin-lipid liposomes
3. The influence of in vivo treatment of skin with liposomes on the topical absorption of a hydrophilic and a hydrophobic drug in vitro
4. Interaction of liposomes with human skin in vitro - The influence of lipid composition and structure
5. Interactions between liposomes and human skin in vitro, a confocal laser scanning microscopy study
6. Interactions of elastic and rigid vesicles with human skin in vitro: Electron microscopy and two-photon excitation microscopy
7. Ultra-high efficiency of drug and peptide transfer through the intact skin by means of novel drug-carriers, Transfersomes
8. Ultraflexible vesicles, Transfersomes, have an extremely low pore penetration resistance and transport therapeutic amounts of insulin across the intact mammalian skin
9. Noninvasive percutaneous induction of topical analgesia by a new type of drug carrier, and prolongation of local pain insensitivity by anesthetic liposomes
10. Oestradiol skin delivery from ultradeformable liposomes: Refinement of surfactant concentration
11. Lecithin vesicular carriers for transdermal delivery of cyclosporin A
12. Transdermal delivery of insulin in mice by using lecithin vesicles as a carrier
13. Elasticity of vesicles assessed by electron spin resonance, electron microscopy and extrusion measurements
14. Elasticity of vesicles affects hairless mouse skin structure and permeability
15. Pergolide. A review of its pharmacological properties and therapeutic potential in Parkinson's disease
16. The preparation and properties of niosomes - Non-ionic surfactant vesicles
17. Lipid polymorphism as observed by cryo-electron microscopy
18. Lipid vesicles penetrate into intact skin owing to the transdermal osmotic gradients and hydration force
19. Transdermal immunisation with an integral membrane component, gap junction protein, by means of ultradeformable drug carriers, transfersomes
20. Interaction between elastic and rigid vesicles with human skin in vivo