Synthesis and biological evaluation of phospholane and dihydrophosphole analogues of the glutamate receptor agonist AP4

Journal of the Chemical Society. Perkin Transactions 1

Volumn 2, Issue 14, 2002, Pages 1625-1627

  Conway, Stuart J ^a,b   Miller, Jacqueline C ^b   Bond, Andrew D ^a   Clark, Barry P ^c   Jane, David E ^b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

^c ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACIDITY; ADDITION REACTIONS; AMINO ACIDS; BIOLOGY; CONFORMATIONS; HYDROGENATION; PHARMACOKINETICS; SYNTHESIS (CHEMICAL);

CHELETROPIC CYCLOADDITION; ETHYLENEDIAMINETETRAACETIC ACID; METABOTROPIC GLUTAMATE RECEPTOR AGONIST; PHOSPHINIC ACID; RETROSYNTHESIS;

PHOSPHORUS COMPOUNDS;

EID: 0035996940     PISSN: 14727781     EISSN: 13645463     Source Type: Journal    
DOI: 10.1039/b204891d     Document Type: Article

References (8)

1. D.D. Schoepp, D.E. Jane, J.A. Monn Neuropharmacology 1999, 38, 1431.
2. S.J. Conway, J.C. Miller, P.A. Howson, B.P. Clark, D.E. Jane Bioorg. Med. Chem. Lett. 2001, 11, 777.
3. R.P. Polniaszek J. Org. Chem. 1992, 57, 5189.
4. T. Tanaka, S. Tamatsukuri, M. Ikehara Tetrahedron Lett. 1986, 199.
5. K. Butterfield, E.J. Thomas J. Chem. Soc., Perkin Trans. 1 1998, 737.
6. H.T. Bucherer, V.A. Libe J. Prakt. Chem. 1934, 141, 5.
7. H-.J. Kang, H-.S. Jeong Bull. Korean Chem. Soc. 1996, 17, 5.
8. R.H. Evans, A.A. Francis, A.W. Jones, D.A.S. Smith, J.C. Watkins Br. J. Pharmacol. 1982, 75, 65.