Effects of angiotensins II and IV on blood pressure, renal function, and PAI-1 expression in the heart and kidney of the rat

Pharmacology

Volumn 66, Issue 1, 2002, Pages 26-30

  Abrahamsen, Christian T ^a   Pullen, Mark A ^a   Schnackenberg, Christine G ^a   Grygielko, Eugene T ^a   Edwards, Richard M ^a   Laping, Nicholas J ^a   Brooks, David P ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

Angiotensin II; Angiotensin IV; Plasminogen activator inhibitor 1

Indexed keywords

ANGIOTENSIN; ANGIOTENSIN II [3-8]; MESSENGER RNA; PLASMINOGEN ACTIVATOR INHIBITOR 1; TRANSFORMING GROWTH FACTOR BETA1; ANGIOTENSIN II; ANGIOTENSIN II, DES ASP(1) DES ARG(2) ILE(5); ANGIOTENSIN II, DES-ASP(1)-DES-ARG(2)-ILE(5)-; DRUG DERIVATIVE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; CREATININE CLEARANCE; DRUG EFFECT; DRUG INFUSION; GENE EXPRESSION; HEART LEFT VENTRICLE; KIDNEY FUNCTION; MALE; NONHUMAN; OSMOTIC MINIPUMP; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; SYSTOLIC BLOOD PRESSURE; ANIMAL; BIOSYNTHESIS; BLOOD PRESSURE; GENETICS; HEART MUSCLE; KIDNEY; KIDNEY FUNCTION TEST; METABOLISM; PHYSIOLOGY; SPRAGUE DAWLEY RAT; STIMULATION;

ANGIOTENSIN II; ANIMAL; BLOOD PRESSURE; KIDNEY; KIDNEY FUNCTION TESTS; MALE; MYOCARDIUM; PLASMINOGEN ACTIVATOR INHIBITOR 1; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STIMULATION, CHEMICAL; ANIMALS;

EID: 0035995464     PISSN: 00317012     EISSN: None     Source Type: Journal    
DOI: 10.1159/000063252     Document Type: Article

References (14)

1. Angiotensin II stimulates exctracellular matrix protein synthesis through induction of transforming growth factor-beta expression in rat glomerular mesangial cells
2. Angiotensin II regulates the expression of plasminogen activator inhibitor-1 in cultured endothelial cells
3. Transforming growth factor-β stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix
4. ECM degradation by cultured human mesangial cells is mediated by a PA/plasmin/MMP-2 cascade
5. The effect of the heptapeptide (2-8) and hexapeptide (3-8) fragments of angiotensin II on aldosterone secretion
6. Angiotensin induction of PAI-1 expression in endothelial cells is mediated by the hexapeptide angiotensin IV
7. Comparison between carvedilol and captopril in rats with partial ablation-induced chronic renal failure
8. Angiotensin II and gene expression in the kidney
9. Understanding the nature of renal disease progression
10. Angiotensin IV stimulates plasminogen activator inhibitor-1 expression in proximal tubular epithelial cells
11. Dual effects of angiotensin II on the plasminogen/plasmin system in rat mesangial cells
12. Angiotensin-II induction of plasminogen activator inhibitor-1 gene expression in astroglial cells of normotensive and spontaneously hypertensive rat brain
13. Angiotensin II increases plasminogen activator inhibitor type 1 and tissue-type plasminogen activator messenger RNA in cultured rat aortic smooth muscle cells
14. Gene expression in rats with renal disease treated with angiotensin II receptor antagonist, eprosartan