T-786 → C polymorphism of the endothelial nitric oxide synthase gene influences the progression of renal disease

Nephron

Volumn 91, Issue 4, 2002, Pages 747-751

  Asakimori, Yukiteru ^a   Yorioka, Noriaki ^a   Taniguchi, Yoshihiko ^a   Ito, Takafumi ^a   Ogata, Satoshi ^a   Kyuden, Yasufumi ^a   Kohno, Nobuoki ^a  

^a HIROSHIMA UNIV SCHOOL OF MEDICINE   (Japan)

Author keywords

Diabetic nephropathy; End stage renal disease; Endothelial nitric oxide synthase; Gene polymorphism; Nondiabetic nephropathy

Indexed keywords

NITRIC OXIDE SYNTHASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; NOS3 PROTEIN, HUMAN;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DISEASE COURSE; FEMALE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC POLYMORPHISM; GENOTYPE; HEMODIALYSIS; HUMAN; INTRON; KIDNEY DISEASE; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; CASE CONTROL STUDY; ENZYMOLOGY; GENETICS; MIDDLE AGED; PATHOLOGY; RENAL REPLACEMENT THERAPY;

ADULT; AGED; CASE-CONTROL STUDIES; DISEASE PROGRESSION; FEMALE; HUMANS; KIDNEY DISEASES; LINKAGE DISEQUILIBRIUM; MALE; MIDDLE AGED; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE III; POLYMORPHISM, GENETIC; RENAL DIALYSIS;

EID: 0035995384     PISSN: 00282766     EISSN: None     Source Type: Journal    
DOI: 10.1159/000065041     Document Type: Article

References (19)

1. Effects of acute nitric oxide inhibition on rat glomerular microcirculation
2. Role of endothelium-derived relaxing factor in regulation of renal hemodynamic responses
3. Chronic blockade of nitric oxide synthesis in the rat produces systemic hypertension and glomerular damage
4. NO at work
5. Gene structure, polymorphism and mapping of the human endothelial nitric oxide synthase gene
6. Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene
7. Isolation of nitric oxide synthase, a calmodulin-requiring enzyme
8. A smoking-dependent risk of coronary artery disease associated with a polymorphism of endothelial nitric oxide synthase gene
9. Evidence of association of the ecNOS gene polymorphism with plasma NO metabolite levels in humans
10. High accumulation of endothelial nitric oxide synthase (ecNOS): A gene polymorphism in patients with end-stage renal disease
11. Endothelial nitric oxide synthase gene polymorphism in intron 4 affects the progression of renal failure in non-diabetic renal diseases
12. Endothelial nitric oxide synthase intron 4 polymorphism influences the progression of renal disease
13. 786 → C mutation in the 5′-flanking region of the endothelial nitric oxide synthase gene is associated with coronary spasm
14. Risk of advanced diabetic nephropathy in type 1 diabetes is associated with endothelial nitric oxide synthase gene polymorphism
15. Nitric oxide modulates the synthesis of extracellular matrix proteins in cultured rat mesangial cells
16. Nitric oxide stimulates the activity of a 72-kDa neutral matrix metalloproteinase in cultured rat mesangial cells
17. High glucose inhibits nitric oxide production in cultured rat mesangial cells
18. Attenuated glomerular cGMP production and renal vasodilatation in streptozocin-induced diabetic rats
19. 786 → C and missense Glu298Asp variants