An improved method for the preparation of [11C]verapamil

Applied Radiation and Isotopes

Volumn 57, Issue 4, 2002, Pages 505-507

  Wegman, T D ^a   Maas, B ^a   Elsinga, P H ^a   Vaalburg, W ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

11C verapamil; Multidrug resistance (MDR); P glycoprotein; Positron emission tomography

Indexed keywords

HUMAN REACTION TIME; METHANOL; SYNTHESIS (CHEMICAL);

OPTIMAL RECATION TEMPERATURE;

ISOTOPES;

METHYL GROUP; METHYLTRIFLATE C 11; NORVERAPAMIL; UNCLASSIFIED DRUG; VERAPAMIL C 11; VERAPAMIL DERIVATIVE; CARBON; DRUG DERIVATIVE; GLYCOPROTEIN P; MESYLIC ACID DERIVATIVE; TRIFLUOROMETHANESULFONIC ACID METHYL ESTER; VERAPAMIL;

ANALYTIC METHOD; ARTICLE; DRUG PURITY; DRUG SYNTHESIS; PRIORITY JOURNAL; RADIOCHEMISTRY; REACTION TIME; REPRODUCIBILITY; TEMPERATURE; CHEMISTRY; COMPUTER ASSISTED EMISSION TOMOGRAPHY; DRUG RESISTANCE; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; SYNTHESIS; TECHNIQUE;

CARBON RADIOISOTOPES; DRUG RESISTANCE, NEOPLASM; HUMAN; MESYLATES; METHODS; P-GLYCOPROTEIN; RADIOCHEMISTRY; TEMPERATURE; TOMOGRAPHY, EMISSION-COMPUTED; VERAPAMIL; HUMANS;

EID: 0035993224     PISSN: 09698043     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-8043(02)00143-4     Document Type: Article

References (11)

1. Carbon-11-labeled daunorubicin and verapamil for probing P-glycoprotein in tumours with PET
2. Expression of a multidrug-resistance gene in human tumors and tissues
3. Complete in vivo reversal of P-glycoprotein pump function in the blood-brain barrier visualised with positron emission tomography
4. 11C]trifluoromethanesulfonic acid methyl ester
5. 11C]raclopride for routine use
6. 11C]methyl triflate
7. 11C] Methyl triflate
8. Multidrug resistance in human cancer
9. Sep pak (TM) as alternative to rotary evaporators for radiopharmaceutical formulations
10. 11C]verapamil for measuring PgP fuction in MDR1A(+/+)/B(+/+) and MDR1A (-/-)/B(-/-) mice
11. 11C]methyl triflate