Microsatellite instability of cancers and concomitant adenomas in synchronous multiple colorectal cancer patients

Journal of Experimental and Clinical Cancer Research

Volumn 21, Issue 2, 2002, Pages 149-154

  Ueda, Eiji ^a   Watanabe, T ^a   Umetani, N ^a   Ishigami, H ^a   Sasaki, S ^a   Nagawa, H ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Carcinogenesis; Colorectal adenoma; Microsatellite instability (MSI); Multiple synchronous colorectal cancer

Indexed keywords

ADENOMA; ADULT; AGED; ARTICLE; CANCER PATIENT; CANCER SURGERY; CANCER TISSUE; CLINICAL FEATURE; COLORECTAL CARCINOMA; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENETIC STABILITY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MICROSATELLITE INSTABILITY; MULTIPLE CANCER; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; COLORECTAL TUMOR; GENETICS; MIDDLE AGED; NUCLEOTIDE SEQUENCE; PATHOLOGY;

ADENOMA; ADULT; AGED; AGED, 80 AND OVER; COLORECTAL NEOPLASMS; DNA MUTATIONAL ANALYSIS; DNA, NEOPLASM; FEMALE; HUMAN; MALE; MICROSATELLITE REPEATS; MIDDLE AGE; NEOPLASMS, MULTIPLE PRIMARY; POLYMERASE CHAIN REACTION; HUMANS; MIDDLE AGED;

DNA; MICROSATELLITE DNA;

EID: 0035991471     PISSN: 03929078     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Genetic alterations during colorectal-tumor development
2. The human mutator gene homolog MSH 2 and its association with hereditary nonpolyposis colon cancer
3. Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer
4. Mutations of two PMS homologues in hereditary nonpolyposis colon cancer
5. Mutation in the mismatch repair gene Msh 6 causes cancer susceptibility
6. Mutations of GTBP in genetically unstable cells
7. Clues to the pathogenesis of familial colorectal cancer
8. Replication errors in benign and malignant tumors from hereditary nonpolyposis colorectal cancer patients
9. Analysis of mismatch repair genes in hereditary non-polyposis colorectal cancer patients
10. Molecular nature of colon tumors in hereditary nonpolyposis colon cancer, familial polyposis, and sporadic colon cancer
11. Genetics, natural history, tumor spectrum, and pathology of hereditary nonpolyposis colorectal cancer: An updated review
12. Prognosis of hereditary nonpolyposis colorectal cancer (HNPCC) and the role of Japanese criteria for HNPCC
13. Diagnostic primer sets for microsatellite instability optimized for minimal amount of damaged DNA from colorectal tissue samples
14. Semiautomated assessment of loss of heterozygosity and replication error in tumors
15. Rapid detection of allele loss in colorectal tumours using microsatellites and fluorescent DNA technology
16. Differences in the diagnostic criteria used by Japanese and Western pathologists to diagnose colorectal carcinoma
17. Microsatellite instability in multiple colorectal tumors
18. Incidence of DNA replication errors in patients with multiple primary cancers
19. Frequent replication errors at microsatellite loci in tumors of patients with multiple primary cancers
20. Screening reduces colorectal cancer rate in families with hereditary nonpolyposis colorectal cancer