Flow cytometry of platelets for clinical analysis

Hematology/Oncology Clinics of North America

Volumn 16, Issue 2, 2002, Pages 421-454

  Hickerson, Darren H M ^a   Bode, Arthur P ^b  

^a BD Technologies   (United States)

^b EAST CAROLINA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; IMMUNOGLOBULIN G; BIOLOGICAL MARKER; FIBRINOGEN RECEPTOR; THROMBOCYTE ANTIGEN;

ANALYTIC METHOD; FLOW CYTOMETRY; HEMOSTASIS; HUMAN; HUMAN CELL; HYPERCOAGULABILITY; LIGHT SCATTERING; PRIORITY JOURNAL; RECEPTOR DENSITY; RECEPTOR OCCUPANCY; REVIEW; THROMBOCYTE; THROMBOCYTE ACTIVATION; THROMBOCYTE FUNCTION; BLOOD; BLOOD CLOTTING TEST; BLOOD STORAGE; INSTRUMENTATION; METHODOLOGY; PARTICLE SIZE; PHOTOMETRY; THROMBOCYTE COUNT; THROMBOCYTE DISORDER;

ANTIGENS, HUMAN PLATELET; BIOLOGICAL MARKERS; BLOOD COAGULATION TESTS; BLOOD PLATELET DISORDERS; BLOOD PRESERVATION; CALCIUM; FLOW CYTOMETRY; HEMOSTASIS; HUMAN; IMMUNOGLOBULIN G; NEPHELOMETRY AND TURBIDIMETRY; PARTICLE SIZE; PLATELET ACTIVATION; PLATELET COUNT; PLATELET MEMBRANE GLYCOPROTEINS; HUMANS;

EID: 0035991368     PISSN: 08898588     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0889-8588(01)00017-X     Document Type: Review

References (105)

1. Changes in the platelet membrane glycoprotein IIb-IIIa complex during platelet activation
2. Organization of von Willebrand factor on surface-activated platelets
3. Platelet plasma membrane glycoproteins: Evidence for the presence of nonequivalent disulfide bonds using nonreduced-reduced two-dimensional gel electrophoresis
4. Demonstration of a new glycoprotein Ib-related component in platelet extracts prepared in the presence of leupeptin
5. A new competitive binding enzyme-linked immunosorbant assay for glycocalicin in plasma and platelet concentrate supernatants
6. Fluorescence anisotropy changes in platelet membranes during activation
7. Lectin-receptor interactions in liposomes: Evidence that binding of wheat germ agglutinin to glycoprotein-phosphatidylethanolamine vesicles induces non-bilayer structures
8. Structure of the glycoprotein IbIX complex from platelet membranes
9. 15-Hydroxyeicosatetraenoic acid-mediated potentiation of thrombin-induced platelet functions occurs via enhanced production of phosphoinositide-derived second messengers-sn-1,2-diacylglycerol and inositol-1,4,5-trisphosphate
10. Transmembrane calcium influx associated with von Willebrand factor binding to gplb in the initiation of shear-induced platelet aggregation
11. Flow cytometric measurements of cytoplasmic calcium changes in human platelets
12. Platelet glycoprotein Ib beta is phosphorylated on serine 166 by cyclic AMP-dependent protein kinase
13. Effect of calcium on protein composition of human platelet cytoskeletons
14. i in exocytosis and transbilayer movement in human platelets surface-labeled with the fluorescent probe TMA-DPH
15. Localization of internal pools of membrane glycoproteins involved in platelet adhesive responses
16. Microtubule coils versus the surface membrane cytoskeleton in maintenance and restoration of platelet discoid shape
17. Regulation of glycoprotein IIB/IIIA exposure on platelets stimulated with alpha-thrombin
18. Shear-induced platelet aggregation requires von Willebrand factor and platelet membrane glycoproteins Ib and Ilb-IIIa
19. Effects of EDTA on membrane glycoproteins IIbIIIa complex analysis using flow cytometry
20. Complex formation of platelet membrane glycoproteins IIb and IIIa with fibrinogen
21. ++ on the surface of human platelets
22. ++ influx into stimulated platelets
23. A platelet alpha-granule membrane protein GMP-140 is expressed on the plasma membrane after activation
24. Platelet dense granule membranes contain both granulophysin and p-selectin
25. T cells bind to the endothelial adhesion molecule GMP-140 p-selection
26. Activation affects access to the platelet receptor for adhesive glycoproteins
27. Delayed accumulation of diacylglycerol in platelets as a mechanism for regulation of onset of aggregation and secretion
28. Application of light-scattering theory to the optical effects associated with the morphology of blood platelets
29. Calcium and calmodulin in the regulation of blood cell functions: A mini-review
30. Improved sensitivity in flow cytometric intracellular ionized calcium measurement using Fluo3/Fura Red fluorescence ratios
31. The flow cytometric kinetic analysis tube: A novel direct agonist injection system for calcium flux studies on the flow cytometer
32. Glanzmann's thrombasthenia: The spectrum of clinical disease
33. Inherited abnormalities of the platelet membrane: Glanzmann thrombasthenia, Bernard-Soulier syndrome, and other disorders
34. Rapid heterozygote detection in Glanzmann's thrombasthenia
35. The expression of glycoproteins on single blood platelets from healthy individuals and from patients with congenital bleeding disorders
36. Bernard-Soulier syndrome: Quantitative characterization of megakaryocytes and platelets by flow cytometric and platelet kinetic measurements
37. Flow cytometry: Its applications to immunohaematology
38. Platelet immunoglobulin G: Its significance for the evaluation of thrombocytopenia and for understanding the origin of α-granule proteins
39. Flow cytometric measurement of platelet-associated immunoglobulin
40. Platelet-associated IgG assay using flow cytometric analysis
41. Flow cytometric measurement of anti-platelet antibodies
42. Detection of platelet-associated immunoglobulin in immune thrombocytopenia by flow cytometry
43. International study to compare antigen-specific methods used for the measurement of antiplatelet autoantibodies
44. Idiopathic thrombocytopenia purpura: A practice guideline developed by explicit methods for the American Society of Hematology
45. Platelet immunology
46. Antenatal platelet antibody testing by flow cytometry - Results of a pilot study
47. Applications of flow cytometry in transfusion medicine
48. Flow cytometric measurements of platelet function and reticulated platelets
49. Reticulated platelets in the evaluation of thrombopoetic disorders
50. New antiplatelet agents: Platelet GPIIb/IIIa antagonists
51. Effect of glycoprotein IIbIIIa inhibitors on CD62p expression, platelet aggregates, and microparticles in vitro
52. Quantitative detection of platelet GPIIb-IIIa receptor antagonist activity using a flow cytometric method
53. Platelet GPIIbIIIa receptor occupancy studies using a novel fluorescinated cyclic Arg-Gly-Asp peptide
54. Heterogeneity of fibrinogen receptor expression on platelets activated in normal plasma with ADP: Analysis by flow cytometry
55. A GP IIIa ligand-induced binding site antibody detects multiple GP IIb-IIIa conformations, and its binding is modulated by various ligands
56. Expression of ligand-induced binding sites on glycoprotein IIb/IIIa complexes and the effect of various inhibitors
57. First report of an intravenous and oral glycoprotein IIb/IIIa inhibitor (RPR 109891) in patients with recent acute coronary syndromes: Results of the TIMI 15A and 15B trials
58. Point-of-care measured platelet inhibition correlates with a reduced risk of an adverse cardiac event after percutaneous coronary intervention: Results of the GOLD multicenter study
59. Platelet activation in unstable angina
60. Flow cytometric parameters for characterizing platelet activation by measuring P-Section (CD62) expression: Theoretical consideration and evaluation in thrombin-treated platelet populations
61. Can flow cytometry detect successful ticlopidine treatment in patients with VVI pacemakers?
62. Application of flow cytometry to blood platelets
63. Comparison of platelet activation in unstable and stable angina pectoris and correlation with coronary angiographic findings
64. Flow cytometric detection of activated platelets in pregnant women prior to the development of pre-eclampsia
65. Laboratory diagnosis of heparin-induced thrombocytopenia: Advantages of a functional flow cytometric test in comparison to the heparin-induced platelet-activation test
66. Evaluation of platelet function by flow cytometry
67. Platelet function testing by flow cytometry
68. 2+ transport in unstimulated platelets of essential hypertensives and their blood relatives
69. Increased calcium stores in platelets from African Americans
70. Dysfunction of calcium handling by smooth muscle in hypertension
71. Platelet calcium linked abnormalities in essential hypertension
72. Platelet membrane calmodulin-stimulated calciumadenosine triphosphatase: Altered activity in essential hypertension
73. Platelet calcium homeostasis is abnormal in patients with severe arteriosclerosis
74. Isolation of human platelet membrane microparticles from plasma and serum
75. Vesiculation of platelets during in vitro aging
76. Assessment of in vitro-generated platelet microparticles using a modified flow cytometric strategy
77. Characterization and quantitation by flow cytometry of membranous microparticles formed during activation of platelet suspensions with ionophore or thrombin
78. Assessment of platelet activation by coronary sinus blood sampling during balloon angioplasty and directional coronary atherectomy
79. Preservation of platelet function after cardiac surgery and apheresis
80. Bleeding complications associated with cardiopulmonary bypass
81. Clinical significance of platelet microparticles in autoimmune thrombocytopenias
82. Sera from patients with heparin-induced thrombocytopenia generate platelet-derived microparticles with procoagulant activity: An explanation for the thrombotic complications of heparin-induced thrombocytopenia
83. A diagnostic test for heparininduced thrombocytopenia: Detection of platelet microparticles using flow cytometry
84. Platelet membrane glycoproteins: Alteration during storage of human platelet concentrates
85. Glycoprotein changes in fresh vs. room temperature-stored platelets and their buoyant density cohorts
86. The use of functional and quantitative assays to study glycoprotein Ib in platelets stored under various in vitro conditions
87. Altered expression of platelet surface glycoproteins during storage
88. Platelet storage results in a redistribution of glycoprotein Ib molecules
89. Effect of platelet activation inhibitors on loss of glycoprotein Ib during storage of platelet concentrates
90. Platelet membrane glycoproteins and platelet functions during storage in the presence of a proteinase inhibitor
91. Thrombin-induced changes in platelet membrane glycoproteins Ib, IX, and IIb-IIIa complex
92. Alterations of the levels of glycoproteins Ib-IX and IIb-IIIa in platelets stored at 22°C
93. Platelet activation may explain the storage lesion in platelet concentrates
94. Detection of platelet activation with monoclonal antibodies and flow cytometry
95. Activation in stored platelet concentrates: Correlation between membrane expression of P-selectin, glycoprotein IIb/IIIa, and β-thromboglobulin release
96. Progressive platelet activation with storage: Evidence for shortened survival of activated platelets after transfusion
97. Detection of plasmapheresis-induced platelet activation using monoclonal antibodies
98. In vivo tracking of platelets: Circulating degranulated platelets rapidly lose surface P-selectin but continue to circulate and function
99. Detection and significance of alpha granule membrane protein 140 expression on platelets collected by apheresis
100. Analysis of platelet factor 3 in platelet concentrates stored for transfusion
101. Platelet storage lesion: Formation of platelet fragments with platelet factor 3 activity
102. Effect of cold storage on platelet glycoprotein IB and vesiculation
103. Microvesicles in blood components: Laboratory and clinical aspects