Adenylyl cyclase activity mediated by β-adrenoceptors in immortalized human trabecular meshwork and non-pigmented ciliary epithelial cells

Journal of Ocular Pharmacology and Therapeutics

Volumn 18, Issue 3, 2002, Pages 221-230

  Crider, Julie Y ^a   Sharif, Najam A ^a  

^a ALCON RESEARCH LTD   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 ISOPROPYLAMINO 1 (7 METHYL 4 INDANYLOXY) 2 BUTANOL; ADENYLATE CYCLASE; ADRENALIN; ATENOLOL; BETA ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CYCLIC AMP; DEXTROBETAXOLOL; DOPAMINE; ISOPRENALINE; LEVOBETAXOLOL; LEVOBUNOLOL; NORADRENALIN; PHENYLEPHRINE; PROPRANOLOL; SALBUTAMOL; UNCLASSIFIED DRUG;

AQUEOUS HUMOR FLOW; ARTICLE; CELL IMMORTALIZATION; CILIARY BODY EPITHELIUM; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME IMMUNOASSAY; HUMAN; HUMAN TISSUE; TRABECULAR MESHWORK; CELL CULTURE; CILIARY BODY; COMPARATIVE STUDY; CYTOLOGY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; EPITHELIUM CELL; METABOLISM;

ADENYLATE CYCLASE; ADRENERGIC BETA-AGONISTS; ADRENERGIC BETA-ANTAGONISTS; CELLS, CULTURED; CILIARY BODY; CYCLIC AMP; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL CELLS; HUMANS; TRABECULAR MESHWORK;

EID: 0035990071     PISSN: 10807683     EISSN: None     Source Type: Journal    
DOI: 10.1089/108076802760116142     Document Type: Article

References (35)

1. Topical ophthalmic beta-blockers: A comparative review
2. Ocular β-blockers in glaucoma management
3. Current trends in antiglaucoma therapy
4. The mechanism of betaxolol, a new ocular hypotensive agent
5. Effects of norepinephrine, isoproterenol and sympathetic stimulation on aqueous humor dynamics in vervet monkeys
6. Selective destruction of the pigmented epithelium in the ciliary body of the eye
7. Adenosine 3′,5′-mono-phosphate increases the outflow of the aqueous humor from the rabbit eye
8. Influence of cyclic nucleotides on outflow facility in the vervet monkey
9. Effect of β-adrenergic agonists on paracellular width and fluid flow across outflow pathway cells
10. Na-K-C 1 cotransport regulates intracellular volume and monolayer permeability of trabecular meshwork cells
11. 2-adrenergic receptors
12. β-adrenergic receptors in human trabecular meshwork
13. Characterization of beta-adrenergic receptors in cultured human trabecular cells and in human trabecular meshwork
14. Preliminary characterization of a transformed cell strain derived from human trabecular meshwork
15. Pharmacological characterization of bradykinin receptors coupled to phosphoinositide turnover in SV40-immortalized human trabecular meshwork cells
16. Prostaglandin DP receptors positively coupled to adenylyl cyclase in embryonic bovine tracheal (EbTr) cells: Pharmacological characterization using agonists and antagonists
17. 2 receptor in human nonpigmented ciliary epithelial cells
18. FP prostaglandin receptors mediating inositol phosphate generation and calcium mobilization in Swiss 3T3 cells: A pharmacological study
19. 50) of an enzymatic reaction
20. Adrenergic drug effects on cyclic AMP in cultured human trabecular meshwork cells
21. Trabecular meshwork cells culture in glaucoma research: Evaluation of biological activity and structural properties of human trabecular cells in vitro
22. Isolation and evaluation of target cells in glaucoma research: Hormone receptors and drug responses
23. Effects of betaxolol on epinephrine stimulated cyclic-AMP levels in human trabecular meshwork cells
24. TM) and other β-adrenergic antagonists: Preclinical pharmacology, IOP-lowering activity and sites of action in human eyes
25. Stereospecificity of beta adrenergic antagonists: R-enantiomers show increased selectivity for beta-2 receptors in ciliary process
26. Modulation of Na/K-ATPase activity by isoproterenol and propranolol in human non-pigmented ciliary epithelial cells
27. - cotransport in fetal non-pigmented ciliary epithelial cells
28. Flow of aqueous humor in humans
29. Timolol may inhibit aqueous humor secretion by cAMP-independent action on ciliary epithelial cells
30. Receptor-responses in fresh human ciliary muscle
31. Distribution and properties of beta-adrenergic receptors in human iris-ciliary body
32. Direct involvement of trabecular meshwork in the regulation of aqueous humor outflow
33. The regulation of trabecular meshwork and ciliary muscle contractility
34. Functional morphology of the trabecular meshwork in primate eyes