Up-regulation of liver glucose-6-phosphatase in x-linked hypophosphatemic mice

Hormone and Metabolic Research

Volumn 34, Issue 6, 2002, Pages 288-292

  Xie, W ^a   Mechin M C ^a   Dubois, S G ^b   Lajeunesse, D ^b   Van de Werve, Gerald ^a  

^a NOTRE DAME HOSPITAL   (Canada)

^b CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Glucose Intolerance; Mouse Liver; Phosphate Homeostasis

Indexed keywords

CYCLIC AMP; GLUCOSE; GLUCOSE 6 PHOSPHATASE; INSULIN; 5' NUCLEOTIDASE; ANTIPORTER; GLUCOSE 6 PHOSPHATE(TRANSPORTER); GLUCOSE 6-PHOSPHATE(TRANSPORTER); GLUCOSE TRANSPORTER; GLYCOPROTEIN; MESSENGER RNA; NT5C3 PROTEIN, HUMAN; PHOSPHOTRANSFERASE; SLC37A4 PROTEIN, MOUSE; SLC37A4 PROTEIN, RAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIET; ENZYME ACTIVITY; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE INTOLERANCE; GLUCOSE METABOLISM; INSULIN BLOOD LEVEL; MALE; MOUSE; NONHUMAN; PHOSPHATE DEFICIENCY; PHOSPHATE METABOLISM; PRIORITY JOURNAL; VITAMIN D RESISTANT RICKETS; ANIMAL; BLOOD; C57BL MOUSE; CHEMISTRY; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETIC LINKAGE; GENETICS; HYPOPHOSPHATEMIA; LIVER; LIVER MICROSOME; METABOLISM; NORTHERN BLOTTING; WESTERN BLOTTING; X CHROMOSOME;

ANIMALIA; MURINAE;

5'-NUCLEOTIDASE; ANIMALS; ANTIPORTERS; BLOOD GLUCOSE; BLOTTING, NORTHERN; BLOTTING, WESTERN; CYCLIC AMP; GENE EXPRESSION REGULATION; GLUCOSE-6-PHOSPHATASE; GLYCOPROTEINS; HYPOPHOSPHATEMIA, FAMILIAL; INSULIN; LINKAGE (GENETICS); LIVER; MALE; MICE; MICE, INBRED C57BL; MICROSOMES, LIVER; MONOSACCHARIDE TRANSPORT PROTEINS; PHOSPHOTRANSFERASES; RNA, MESSENGER; X CHROMOSOME;

EID: 0035988632     PISSN: 00185043     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2002-33256     Document Type: Article

References (28)

1. Glucose-6-phosphatase structure, regulation, and function: An update
2. Mutations in the glucose-6-phosphatase gene that cause glycogen storage disease type 1a
3. Sequence of a putative glucose-6-phosphate translocase, mutation in glycogen storage disease type 1b
4. New lessons in the regulation of glucose metabolism taught by the glucose 6-phosphatase system
5. Diabetes affects similarly the catalytic subunit and putative glucose-6-phosphate translocase of glucose-6-phosphatase
6. Distinct hormone stimulation and counteraction by insulin of the expression of the two components of glucose 6-phosphatase in HepG2 cells
7. Perturbation of fuel homeostasis caused by over-expression of the glucose-6-phosphatase catalytic subunit in liver of normal rats
8. New insights into the pathogenesis of inherited phosphate wasting disorders
9. Direct demonstration of a humorally-mediated inhibition of renal phosphate transport in the Hyp mouse
10. A gene (PEX) with homologies to endopeptidases is mutated in patients with X-linked hypophosphatemic rickets
11. cDNA cloning of the murine Pex gene implicated in X-linked hypophosphatemia and evidence for expression in bone
12. Cloning and sequencing of human PEX from a bone cDNA library: Evidence for its developmental stage-specific regulation in osteoblasts
13. Hypophosphatemia and glucose intolerance: Evidence for tissue insensitivity to insulin
14. Effects of hypophosphatemia on glucose tolerance and insulin secretion
15. i-deficient diet
16. Dietary phosphate deprivation in rats affects liver cyclic AMP, glycogen, key steps of gluconeogenesis and glucose production
17. Ontogeny of the catalytic subunit and putative glucose-6-phosphate transporter proteins of the rat microsomal liver glucose-6-phosphatase system
18. X-linked hypophosphatemia: A homologous disorder in humans and mice
19. Identification of regulatory sequences and binding proteins in the type II sodium/phosphate cotransporter NPT2 gene responsive to dietary phosphate
20. Evidence for an intrinsic renal tubular defect in mice with genetic hypophosphatemic rickets
21. Secondary hyperparathyroidism in X-linked hypophosphatemic mice
22. Phosphate depletion impairs insulin secretion by pancreatic islets
23. Stanniocalcin 2: Characterization of the protein and its localization to human pancreatic alpha cells
24. PHEX gene and hypophosphatemia
25. Cloning and characterization of FGF-23 as a causative factor of tumor-induced osteomalacia
26. FGF-23 inhibits renal tubular phosphate transport and is a PHEX substrate
27. MEPE, a new gene expressed in bone marrow and tumors causing osteomalacia
28. Mepe, the gene encoding a tumor-secreted protein in oncogenic hypophosphatemic osteomalacia, is expressed in bone