Gastrointestinal tolerability of ibuprofen compared with paracetamol and aspirin at over-the-counter doses

Journal of International Medical Research

Volumn 30, Issue 3, 2002, Pages 301-308

  Rampal, P ^a   Moore, N ^a   Van Ganse, E ^a   Le Parc, J M ^a   Wall, R ^a   Schneid, H ^a   Verriere F ^a  

^a CENTRE HOSPITALIER UNIVERSITAIRE DE NICE   (France)

Author keywords

Analgesics; Aspirin; Gastrointestinal tolerability; Ibuprofen; Paracetamol

Indexed keywords

ACETYLSALICYLIC ACID; IBUPROFEN; NON PRESCRIPTION DRUG; PARACETAMOL;

ABDOMINAL PAIN; ADULT; AGED; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DRUG INDICATION; DRUG TOLERABILITY; DYSPEPSIA; FEMALE; GASTROINTESTINAL SYMPTOM; GENDER; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NAUSEA; PAIN; RANDOMIZED CONTROLLED TRIAL; SINGLE BLIND PROCEDURE; COMPARATIVE STUDY; DIGESTIVE SYSTEM; DRUG EFFECT; OUTCOME ASSESSMENT;

ACETAMINOPHEN; ASPIRIN; DIGESTIVE SYSTEM; FEMALE; HUMANS; IBUPROFEN; MALE; OUTCOME ASSESSMENT (HEALTH CARE);

EID: 0035988497     PISSN: 03000605     EISSN: None     Source Type: Journal    
DOI: 10.1177/147323000203000311     Document Type: Article

References (26)

1. A large scale randomised clinical trial comparing the tolerability of aspirin, ibuprofen and paracetamol for short-term analgesia
2. When and how to do multiple comparisons
3. An assessment of the safety of pediatric ibuprofen: A practitioner-based randomized clinical trial
4. Gastrointestinal safety and tolerance of ibuprofen at maximum over-the-counter dose
5. Endoscopic studies of gastric and duodenal injury after the use of ibuprofen, aspirin, and other nonsteroidal anti-inflammatory agents
6. Gastrointestinal adverse drug reactions attributed to ibuprofen
7. Risk of upper gastrointestinal bleeding and perforation associated with individual non-steroidal anti-inflammatory drugs
8. Nonsteroidal anti-inflammatory-drug use and increased risk for peptic ulcer disease in elderly persons
9. Risks of bleeding peptic ulcer associated with individual non-steroidal anti-inflammatory drugs
10. Non-steroidal anti-inflammatory drug use in relation to major upper gastrointestinal bleeding
11. Variability in risk of gastrointestinal complications with individual non-steroidal anti-inflammatory drugs: Results of a collaborative meta-analysis
12. Prophylactic aspirin and risk of peptic ulcer bleeding
13. Risk of aspirin-associated major upper-gastrointestinal bleeding with enteric-coated or buffered product
14. Guidelines for approving nonsteroidal antiinflammatory drugs for over-the-counter use
15. Comparison of an anti-inflammatory dose of ibuprofen, an analgesic dose of ibuprofen, and acetaminophen in the treatment of patients with osteoarthritis of the knee
16. Nonsteroidal anti-inflammatory drugs, ulcers and risk: A collaborative meta-analysis
17. Variability in risk of gastrointestinal complications with different nonsteroidal anti-inflammatory drugs
18. Ibuprofen and paracetamol: Relative safety in non-prescription dosages
19. Safety profile of over-the-counter naproxen sodium
20. Non-prescription ibuprofen: Side effect profile
21. The safety profile of non-prescription ibuprofen in multiple-dose use: A meta-analysis
22. Reporting of adverse effects in clinical trials should be improved: Lessons from acute postoperative pain
23. GI bleeding in relation to analgesic use
24. Gastrointestinal complications of prescription and over-the-counter nonsteroidal anti-inflammatory drugs: A view from the ARAMIS database